store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(S, R, S)-AHPC-PEG3-N3 (VHL Ligand-Linker Conjugates 8) is a synthesized E3 ligase ligand-linker conjugate. (S, R, S)-AHPC-PEG3-N3 incorporates the (S, R, S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
2 mg | 在庫あり | ¥ 8,500 | |||
5 mg | 在庫あり | ¥ 13,000 | |||
10 mg | 在庫あり | ¥ 20,500 | |||
25 mg | 在庫あり | ¥ 35,500 | |||
50 mg | 在庫あり | ¥ 45,500 | |||
100 mg | 在庫あり | ¥ 66,500 |
説明 | (S, R, S)-AHPC-PEG3-N3 (VHL Ligand-Linker Conjugates 8) is a synthesized E3 ligase ligand-linker conjugate. (S, R, S)-AHPC-PEG3-N3 incorporates the (S, R, S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology. |
In vitro | (S,R,S)-AHPC-PEG3-N3 is extracted from patent WO/2016/146985A1, figure 11. PROTAC has been developed with an A-L-B structure that can tether a bromodomain inhibitor via a moiety which binds to a protein within the bromo- and Extra-terminal (BET) family of proteins to a small molecule E3 ubiquintin ligase protein binding ligand compound via a suitable linker[1][2]. |
別名 | VHL Ligand-Linker Conjugates 8, VH032-PEG3-N3, E3 ligase Ligand-Linker Conjugates 12 |
分子量 | 645.77 |
分子式 | C30H43N7O7S |
CAS No. | 1797406-80-4 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (77.43 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
(S,R,S)-AHPC-PEG3-N3 1797406-80-4 Others PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase (S,R,S) AHPC PEG3 N3 (S,R,S)-AHPC-PEG-3-N3 Inhibitor inhibit E3 Ligase Ligand-Linker Conjugates VHL Ligand-Linker Conjugates 8 AHPC-PEG3-N3 VH032-PEG3-N3 (S,R,S)AHPCPEG3N3 E3 ligase Ligand-Linker Conjugates 12 inhibitor