Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(Z)-Guggulsterone inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
5 mg | 在庫あり | ¥ 21,000 | |||
10 mg | 在庫あり | ¥ 30,000 | |||
25 mg | 在庫あり | ¥ 60,000 | |||
50 mg | 在庫あり | ¥ 90,000 | |||
100 mg | 在庫あり | ¥ 135,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 23,000 |
説明 | (Z)-Guggulsterone inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis. |
In vitro | In HUVEC, Z-guggulsterone (10, 20 μM; 24 or 48 hours) induces a reduction in the level of VEGF-R2 protein [1]. |
In vivo | In tumor volume and wet tumor weight, Z-guggulsterone (p.o.; 1 mg; 5 times/week) causes a statistically significant reduction [1]. |
分子量 | 312.45 |
分子式 | C21H28O2 |
CAS No. | 39025-23-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mg/mL (32.01 mM)
You can also refer to dose conversion for different animals. 詳細
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(Z)-Guggulsterone 39025-23-5 Angiogenesis Apoptosis Cytoskeletal Signaling PI3K/Akt/mTOR signaling Tyrosine Kinase/Adaptors Akt VEGFR inhibit Protein kinase B PKB Inhibitor Guggulsterone (Z) Guggulsterone Vascular endothelial growth factor receptor (Z)Guggulsterone inhibitor