Powder: -20°C for 3 years | In solvent: -80°C for 1 year
11β-HSd1-in-11 is a potent and competitive inhibitor of 11-β-hydroxysteroid dehydrogenase 1 (11β-HSD1) IN rats and humans with IC50 values of 0.34 μM and 0.13 μM, respectively. 11β-Hsvd1-in-11 is a compound used as a chemical compound. 11β-HSD1-IN-11 is a hormone involved in regulating various physiological processes, such as metabolism, inflammation, and stress responses. 11β-Hd1-in-11 is a potential compound for the treatment of metabolic disorders, obesity, and certain inflammatory conditions.
説明 | 11β-HSd1-in-11 is a potent and competitive inhibitor of 11-β-hydroxysteroid dehydrogenase 1 (11β-HSD1) IN rats and humans with IC50 values of 0.34 μM and 0.13 μM, respectively. 11β-Hsvd1-in-11 is a compound used as a chemical compound. 11β-HSD1-IN-11 is a hormone involved in regulating various physiological processes, such as metabolism, inflammation, and stress responses. 11β-Hd1-in-11 is a potential compound for the treatment of metabolic disorders, obesity, and certain inflammatory conditions. |
In vivo | A single administration of the 11β-HSD1 inhibitor, Merck 544, significantly decreased the concentration of 11β-HSD1-IN-11 (Compound c1a) (15 mg/kg; oral gavage; once) in rat liver[1]. |
分子量 | 328.31 |
分子式 | C15H11F3O3S |
CAS No. | 859721-81-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (167.52 mM)
You can also refer to dose conversion for different animals. 詳細
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11β-HSD1-IN-11 859721-81-6 Metabolism Dehydrogenase 11b-HSD1-IN-11 11beta-HSD1-IN-11 11βHSD1IN11 Inhibitor inhibitor inhibit