Powder: -20°C for 3 years | In solvent: -80°C for 1 year
N-(4-(aminomethyl)-2,6-dimethylphenyl)-5 is a potent, selective antagonist of the sphingosine-1-phosphate receptor 4 (S1P4). CYM50358 inhibits S1P4 with an IC50 of 25 nM.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 12,000 |
5 mg | 在庫あり | ¥ 28,000 |
10 mg | お問い合わせ | ¥ 45,500 |
25 mg | お問い合わせ | ¥ 104,500 |
50 mg | お問い合わせ | ¥ 154,500 |
100 mg | お問い合わせ | ¥ 219,500 |
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 30,500 |
説明 | N-(4-(aminomethyl)-2,6-dimethylphenyl)-5 is a potent, selective antagonist of the sphingosine-1-phosphate receptor 4 (S1P4). CYM50358 inhibits S1P4 with an IC50 of 25 nM. |
ターゲット&IC50 | S1PR4:25 nM |
In vitro | N-(4-(aminomethyl)-2,6-dimethylphenyl)-5 shows less potent inhibition of S1PR1(IC50=6.4μM)[1].N-(4-(aminomethyl)-2,6-dimethylphenyl)-5(10μM)has no effect on the collagen-induced HSP27 phosphorylation,markedly reverses the suppressive effect of S1P on the collagen-induced phospphorylation of HSP27[2]. |
分子量 | 389.28 |
分子式 | C20H18Cl2N2O2 |
CAS No. | 1314212-39-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 125 mg/mL (321.11 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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CYM50358 1314212-39-9 GPCR/G Protein LPL Receptor CYM 50358 CYM-50358 Lysophospholipid Receptor Inhibitor inhibit S1PR4 inhibitor