Powder: -20°C for 3 years | In solvent: -80°C for 1 year
8-Azaadenosine, a powerful ADAR1 (ADAR1) and A-to-I editing inhibitor, effectively blocks RNA editing and suppresses proliferation, 3D growth, invasion, and migration in thyroid cancer cells.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 8,000 | |||
5 mg | 在庫あり | ¥ 18,500 | |||
10 mg | 在庫あり | ¥ 28,000 | |||
25 mg | 在庫あり | ¥ 62,500 | |||
50 mg | 在庫あり | ¥ 104,500 | |||
100 mg | 在庫あり | ¥ 154,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 20,500 |
説明 | 8-Azaadenosine, a powerful ADAR1 (ADAR1) and A-to-I editing inhibitor, effectively blocks RNA editing and suppresses proliferation, 3D growth, invasion, and migration in thyroid cancer cells. |
In vitro | 8-azaadenosine (8-aza-AR) was a potent inhibitor of purine synthesis de novo, but 8-aza-HR, at concentrations much higher than the inhibitory concentration of 8-aza-AR, did not inhibit this process.?In H. Ep. 2 cells, 8-aza-HR blocked the conversion of orotic acid to uridine nucleotides and caused an accumulation of orotidine.?This inhibition of pyrimidine biosynthesis apparently does not contribute significantly to the cytotoxicity of 8-aza-HR because uridine provided no degree of reversal of its inhibition of the growth of cell cultures. |
分子量 | 268.23 |
分子式 | C9H12N6O4 |
CAS No. | 10299-44-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 250 mg/mL (932.04 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
8-Azaadenosine 10299-44-2 Metabolism Adenosine deaminase thyroid inhibit editing LIN28B invasion proliferation Cal62 migration 8Azaadenosine RNA ADAR1 TPC1 Inhibitor Adenosine Deaminase 8 Azaadenosine inhibitor