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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T79923 | T7 RNA polymerase | DNA/RNA Synthesis | |
T7 RNA polymerase, expressed by Escherichia coli from the T7 bacteriophage RNA polymerase gene, is a highly specific enzyme utilized for in vitro transcription (IVT) of mRNA. This polymerase requires Mg 2+ and selects on... | |||
T79924 | T4 RNA ligase | DNA/RNA Synthesis | |
T4 RNA ligase is an enzyme that facilitates the ligation of single-stranded DNA. It is utilized for the synthesis of enzymatic oligoribonucleotides and the 3′-terminal labeling of RNA [1] [2]. | |||
T74884 | RNA splicing modulator 1 | ||
RNA Splicing Modulator 1 (Compound 233) is a modulator of RNA splicing, exhibiting an AC50 value of less than 100 nM [1]. | |||
T74886 | RNA splicing modulator 3 | ||
RNA Splicing Modulator 3 (Compound 236) is an effective RNA splicing modulator, exhibiting an AC50 value of less than 100 nM [1]. | |||
T74885 | RNA splicing modulator 2 | ||
RNA splicing modulator 2 (compound 256) is a RNA splicing modulator [1] . | |||
T74630 | RNA polymerase II-IN-1 | DNA/RNA Synthesis | |
RNA polymerase II-IN-1 (compound 19iv), an amatoxin, selectively inhibits RNA polymerase II (Pol II) with an IC50 of 36.66 nM. It exhibits heightened cytotoxicity towards cancer cells and reduced toxicity in normal cells... | |||
T74631 | RNA polymerase II-IN-2 | ||
RNA polymerase II-IN-2 (compound 20iii), a potent inhibitor of RNA polymerase II (Pol II) with a K i value of 9.5 nM, demonstrates cytotoxicity against cancer cells, exhibiting toxicity levels 2 and 5 times higher than α... | |||
T81356 | PTBP1-RNA-binding inhibitor P6 TFA | PTBP1 α3-helix derived peptide P6 TFA | |
PTBP1-RNA-binding inhibitor P6 (PTBP1 α3-helix derived peptide P6) TFA is a stapled peptide that acts as an inhibitor for the splicing factor PTBP1, targeting the alternative splicing events this protein regulates. It op... | |||
TD0005 | SYBR GREEN II | SUPER Green II RNA gel stain *10,000× concentrate in DMSO* (Electrophoresis Grade) | |
1) Non-toxicity: belong to flower-stem dye, easy to biodegrade, no carcinogenic toxicity. 2) High sensitivity: at least 100pg ssDNA or RNA can be detected, which is 25 ~ 100 times higher than EB staining. 3) High SIGNal-... | |||
T36971 | 5-Ethynyluridine | Nucleoside Antimetabolite/Analog | |
5-Ethynyluridine is a clickable form of uridine.1It is incorporated into cellular RNA, but not DNA, and has been used to detect transcriptionin vitroandin vivo. 1.Jao, C.Y., and Salic, A.Exploring RNA transcription and t... | |||
T83729 | Tat-CIRP TFA | Tat-Cold-inducible RNA Binding Protein | |
Tat-CIRP, a peptide inhibitor, impedes the protein-protein interaction between myeloid differentiation 2 (MD-2), also known as lymphocyte antigen 96 (LY96), and cold-inducible RNA binding protein (CIRP) by binding to MD-... | |||
T1349 | 5-Fluorouridine | Others , DNA/RNA Synthesis | |
5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine. 5-fluorouridine is a solid. This compound belongs to the pyrimidine nucleosides and analogues. These are compound... | |||
T8354 | Triazavirin | Nucleoside Antimetabolite/Analog , Influenza Virus , DNA/RNA Synthesis | |
Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent. | |||
T1767 | BMH-21 | BMH21 | DNA/RNA Synthesis |
BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX. | |||
T14522 | Beaucage reagent | DNA/RNA Synthesis | |
Beaucage reagent, which is found to be effective in causing DNA cleavage. | |||
T13166 | TK216 | Others , DNA/RNA Synthesis | |
TK216 is a potent inhibitor of E26 transformation-specific (ETS) with anticancer activity. | |||
T12019 | Methylproamine | Others | |
Methylproamine is a DNA-binding radioprotector , acts by repair of transient radiation-induced oxidative species on DNA. | |||
T26674 | AT-130 | AT 130 | HBV , DNA/RNA Synthesis |
AT-130 is a HBV virus inhibitor with improved potency (IC50 = 0.13 μM) and reduced toxicity in the HepAD38 cell line. AT-130 blocks HBV replication at the level of viral RNA packaging. | |||
T6801 | CeMMEC13 | Carboxypeptidase , DNA/RNA Synthesis | |
CeMMEC13 is an isoquinolinone that selectively inhibits the second bromodomain of TAF1 (IC50 = 2.1 μM). | |||
T1154 | Rifaximin | DNA/RNA Synthesis , Antibacterial , Antibiotic | |
Rifaximin is an orally administered, semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity. Rifaximin binds to the beta-subunit of bacterial DNA-dependent RNA polymerase, inhibiting... | |||
T15611 | JH-RE-06 | DNA/RNA Synthesis | |
JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POLζ. JH-RE-06 is an effective REV1-REV7 interface inhibitor (IC50=0.78 μM; Kd=0.42 μM), which targets REV1 that interact... | |||
TP1115 | L-Asparaginase | L-ASNase | Others |
L-Asparaginase (L-ASNase) (L-ASNase), a hydrolase that catalyzes the conversion of L-asparagine, used in acute lymphoblastic leukemia treatment.Asparaginase is an enzyme that is used as a medication. As a medication, L-a... | |||
T3489 | Dasabuvir | ABT-333 | HCV Protease |
Dasabuvir (ABT-333) is a non-nucleoside inhibitor of the hepatitis C virus (HCV) non-structural protein 5B (NS5B), an RNA-dependent RNA polymerase, with potential activity against HCV. Upon administration and after intra... | |||
T8886 | NITD-2 | DNA/RNA Synthesis | |
NITD-2 is a dengue virus (DENV) polymerase inhibitor, inhibits the DENV RdRp-mediated RNA elongation. NITD-2 penetrates cell membrane poorly. Dengue virus (DENV) is the most prevalent mosquito- borne viral pathogen in hu... | |||
T2037 | TH588 | DNA/RNA Synthesis , MTH1 | |
TH588 is nudix hydrolase family inhibitor that effectively and selectively engages and inhibits the MTH1(IC50: 5 nM) in cells. | |||
T8955 | PCNA-I1 | Others | |
PCNA-I1 is an inhibitor targeting PCNA chromatin association in prostate cancer. | |||
T4686 | Simeprevir | TMC435,TMC-435350,Olysio | HCV Protease , SARS-CoV |
Simeprevir (TMC435) is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM. | |||
T2100 | CX-5461 | DNA/RNA Synthesis | |
CX-5461, a selective inhibitor of rRNA synthesis, suppresses Pol I-driven transcription of rRNA. | |||
T16961 | Supinoxin | RX-5902 | Apoptosis , DNA/RNA Synthesis |
Supinoxin (RX-5902) is an orally active inhibitor of phosphorylated-p68 RNA helicase and a potent first-in-class anti-cancer agent. Supinoxin induces cell apoptosis and inhibits the growth of TNBC cancer cell lines (IC50... | |||
T36687 | Ac-rC Phosphoramidite | Nucleoside Antimetabolite/Analog | |
Ac-rC Phosphoramidite can modify phosphodisulfide oligonucleotides. | |||
T2410 | Nedaplatin | NSC 375101D | DNA/RNA Synthesis |
Nedaplatin (NSC-375101D) is a derivative of cisplatin and DNA damage agent for tumor colony forming units (IC50: 94 μM). Containing a novel ring structure in which glycolate is bound to the platinum by a bidentate ligand... | |||
T40168 | DHODH-IN-16 | Dehydrogenase | |
DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human). | |||
T8873 | Bractoppin | Others , DNA/RNA Synthesis | |
Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 μM), which selectively inhibits substrate binding with nanomolar potency in vitro. Structure-activi... | |||
T15235 | Enocitabine | Nucleoside Antimetabolite/Analog , HCV Protease , DNA/RNA Synthesis | |
Enocitabine is a nucleoside analog. Enocitabine inhibits the replication of human cytomegalovirus(HCMV) and it also has antileukemic and antiviral activities. Enocitabine is also a potent DNA replication inhibitor and a ... | |||
T35648 | 4-Thiouridine | Others | |
4-Thiouridine (4-SU) is a photoactivatable ribonucleoside analog that is widely used for RNA analysis, including short-range RNA-RNA crosslinking and nascent RNA labeling. The crosslinking thio moiety is attached directl... | |||
T38889 | Thailanstatin A | ||
Thailanstatin A is an ultra-potent inhibitor of eukaryotic RNA splicing (IC50 =650 nM). Thailanstatin A inhibits multiple cancer cell lines via non-covalent binding to the SF3b subunit of the U2 snRNA subcomplex of the s... | |||
T14501 | BAY-2402234 | Dehydrogenase , DNA/RNA Synthesis | |
BAY-2402234 is an inhibitor of dihydroorotate dehydrogenase (DHODH) for the treatment of myeloid malignancies.BAY 2402234 is a selective low-nanomolar inhibitor of human DHODH enzymatic activity. | |||
T7747 | Datelliptium chloride hydrochloride | DNA/RNA Synthesis | |
Datelliptium chloride hydrochloride is a DNA-intercalating agent derived from ellipticine. with anti-tumor activities. | |||
T36757 | DMT-dU-CE Phosphoramidite | DNA/RNA Synthesis | |
DMT-dU-CE Phosphoramidite is a nucleoside molecule commonly used for the synthesis and sequencing of DNA. | |||
T1233 | Oxolinic acid | Emyrenil,Nidantin,NSC 110364,Dioxacin,Urinox | Dopamine Receptor , DNA/RNA Synthesis , Antibacterial , Antibiotic |
Oxolinic acid (Nidantin) is a synthetic antimicrobial related to NALIDIXIC ACID and used in URINARY TRACT INFECTIONS. | |||
T38237 | 2′-O-Methylcytidine | Nucleoside Antimetabolite/Analog , HCV Protease | |
2'-O-Methylcytidine is a nucleoside derivative and an inhibitor of hepatitis C virus (HCV) non-structural protein 5B (NS5B; IC50= 3.8 μM).1It inhibits HCV replication in a replicon assay (IC50= 21.2 μM). 1.Migliaccio, G.... | |||
T16703 | Quarfloxin | CX-3543 | DNA/RNA Synthesis |
Quarfloxin (CX-3543) is a fluoroquinolone derivative with antineoplastic activity with IC50 values in the nanomolar range in neuroblastoma cells. Quarfloxin disrupts the interaction between the nucleolin protein and a G-... | |||
T40661 | ML-60218 | DNA/RNA Synthesis | |
ML-60218 is an inhibitor of broad-spectrum RNA pol III with IC50s of 32 and 27 μM for Saccharomyces cerevisiae and human. ML-60218 disrupts already assembled viroplasms and hampers the formation of new viroplasms. | |||
T9111 | 8-Azaadenosine | Adenosine deaminase | |
8-Azaadenosine, a powerful ADAR1 (ADAR1) and A-to-I editing inhibitor, effectively blocks RNA editing and suppresses proliferation, 3D growth, invasion, and migration in thyroid cancer cells. | |||
T11020 | DHODH-IN-11 | Dehydrogenase , DNA/RNA Synthesis | |
DHODH-IN-11 is a leflunomide derivative and weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.03. | |||
T4345 | CeMMEC1 | CeMMEC1 HCl | Epigenetic Reader Domain , Carboxypeptidase , DNA/RNA Synthesis |
CeMMEC1 is an inhibitor of BRD4, and also has a great affinity for TAF1(IC50=0.9 μM). | |||
T9103 | BVDV-IN-1 | DNA/RNA Synthesis | |
BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM. It directly binds to a hydrophobic pocket of the BVDV RdRp. It has antiviral activity against BVDV resistant to... | |||
T8747 | Levofloxacin hydrochloride | DNA gyrase , Topoisomerase | |
Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the bacterial cell wall and acts by inh... | |||
T13659 | DMTr-LNA-5MeU-3-CED-phosphoramidite | Nucleoside Antimetabolite/Analog | |
DMTr-LNA-5MeU-3-CED-phosphoramidite is a derivative of nucleoside. | |||
T9121 | AG-636 | Dehydrogenase , DNA/RNA Synthesis | |
AG-636 is a potent, reversible, selective and orally active DHODH inhibitor(IC50 of 17 nM). It has strong anticancer effects. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T13969 | Xanthopterin (hydrate) | Others , DNA/RNA Synthesis | |
Xanthopterin Hydrate is isolated from butterfly wings and could replace folic acid in the nutrition of many animal species. | |||
T13499 | 3-Methyluridine | Endogenous Metabolite | |
3-Methyluridine is a modified nucleoside of cellular RNA. | |||
T40179 | Sodium Camptothecin | DNA/RNA Synthesis | |
Sodium Camptothecin is a plant alkaloid with antitumor activity. Sodium Camptothecin is a reversible RNA synthesis inhibitor. Sodium Camptothecin is an effective adenovirus replication inhibitor. Sodium Camptothecin i... | |||
T2S1635 | 3-Isomangostin | MTH1 | |
3-Isomangostin is a potent human aldose reductase inhibitor with an IC50 of 3.48 uM; it is also an acetylcholinesterase selective inhibitor. 3-Isomangostin has free radical scavenging activity; it shows antiplasmodial ac... | |||
T24729 | Roseoflavin | Antibacterial | |
Roseoflavin, a chemical analog of FMN and riboflavin that has antimicrobial activity, can directly bind to FMN riboswitch aptamers and downregulate the expression of an FMN riboswitch-lacZ reporter gene in B. subtilis. | |||
T21498 | Phleomycin | DNA/RNA Synthesis , Antibacterial , Antibiotic | |
Phleomycin is one of the anticancer glycopeptide antibiotics which cause DNA cleavage. It is similar to Bleomycin which binds and intercalates DNA to damage the integrity of the double helix. | |||
TN1134 | Euscaphic acid | Apoptosis , LDL , PI3K , DNA/RNA Synthesis , NO Synthase , Prostaglandin Receptor | |
Euscaphic acid has anti-diabetic, and anti-inflammatory activities, it inhibits LPS-induced inflammatory responses by interference with the clustering of TRAF6 with IRAK1 and TAK1, resulting in blocking the activation of... | |||
T5901 | 3-Hydroxy-2-methylpyridine | Others | |
3-Hydroxy-2-methylpyridine could as a promising molecular scaffold for the future development of novel fibrillization inhibitors. | |||
T5270 | 5-Methylcytosine | Others , DNA/RNA Synthesis , Endogenous Metabolite | |
5-Methylcytosine is a methylated nucleotide base found in eukaryotic DNA. In animals, the DNA methylation of cytosine to form 5-methylcytosine is found primarily in the palindromic sequence CpG. In plants, the methylated... | |||
T1465 | Mupirocin | Pseudomonic acid,BRL-4910A | DNA/RNA Synthesis , Antibacterial , Antibiotic |
Mupirocin (BRL-4910A) is a RNA synthetase inhibitor antibacterial. It has shown excellent activity against gram-positive staphylococci and streptococci. | |||
T37101 | 1-Hydroxyanthraquinone | DNA/RNA Synthesis | |
1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities. 1-Hydroxyanthraquinone generates strong DNA repair response. | |||
T8148 | Mupirocin calcium hydrate | Mupirocin calcium | Others , Antibacterial , Antibiotic |
Mupirocin calcium hydrate is an antibiotic produced by Pseudomonas fluorescens, showed a high level of activity against staphylococci and streptococci and against certain gram-negative bacteria | |||
TQ0184 | Chebulinic acid | ATPase , Proton pump , DNA/RNA Synthesis , Antibacterial , TGF-beta/Smad | |
Chebulinic acid is a potent inhibitor of M. tuberculosis DNA gyrase. It also can inhibit SMAD-3 phosphorylation and H+ K+-ATPase activity. | |||
T35455 | N-Nitrosodiethylamine | Diethylnitrosamine,NDEA | DNA/RNA Synthesis |
N-Nitrosodiethylamine (NDEA) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in water, tobacco smoke, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitroso... | |||
T6S0232 | Eriodictyol | Huazhongilexone | Influenza Virus , DNA/RNA Synthesis , Nrf2 , Endogenous Metabolite |
1. Eriodictyol (Huazhongilexone) is a flavonoid with anti-inflammatory and antioxidant activities. 2. Eriodictyol may possess antidiabetic properties through increasing glucose uptake and improving insulin resistance. 3.... | |||
T1068 | Dithranol | 1,8,9-trihydroxyanthracene,cignoline,Anthralin | Others , DNA/RNA Synthesis |
Dithranol (cignoline) is an anthracene derivative that disrupts MITOCHONDRIA function and structure and is used for the treatment of DERMATOSES, especially PSORIASIS. It may cause FOLLICULITIS. | |||
T6S0139 | Neobavaisoflavone | Apoptosis , DNA/RNA Synthesis | |
1. Neobavaisoflavone is isolated as a DNA polymerase inhibitor. 2. Neobavaisoflavone might be a potential anabolic agent to treat bone loss-associated diseases. 3. Neobavaisoflavone has anti-inflammatory activity, can si... | |||
T7520 | Deoxycytidine triphosphate | Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Endogenous Metabolite | |
Deoxycytidine triphosphate is a nucleoside triphosphate.It is a raw material in DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing. | |||
T16674 | Pseudouridine | Endogenous Metabolite | |
Pseudouridine is the most abundant modified nucleoside in non-coding RNAs. It enhances the function of transfer RNA and ribosomal RNA by stabilizing RNA structure. | |||
T17143 | Toyocamycin | Vengicide | Apoptosis , Others , IRE1 , Antibiotic , Antifungal |
Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage (IC50: 80 nM). Toyocamycin induces apoptosis. | |||
T6194 | Fidaxomicin | Tiacumicin B,OPT-80,Clostomicin B1,PAR-101 | Apoptosis , DNA/RNA Synthesis , Antibacterial , Antibiotic |
Fidaxomicin (Tiacumicin B) is a semisynthetic macrolide antibiotic used to treat Clostridium difficile-associated diarrhea in adults. Fidaxomicin has minimal systemic absorption and has not been linked to serum enzyme el... | |||
T2998 | Dihydromyricetin | Ampelopsin,Ampeloptin | Influenza Virus , GABA Receptor , DNA/RNA Synthesis , mTOR , Autophagy |
Dihydromyricetin (Ampelopsin) is a natural antioxidant flavonoid from Ampelopsis grossedentata. Dihydromyricetin is a potent inhibitor of dihydropyrimidinase with an IC50 of 48 μM. Dihydromyricetin can activate autophagy... | |||
TN2132 | Quinizarin | 1,4-Dihydroxyanthraquinone | Others , DNA/RNA Synthesis , Antifungal |
Quinizarin (1,4-Dihydroxyanthraquinone) is a natural product | |||
T9715 | Aplidine | SARS-CoV , DNA/RNA Synthesis | |
Aplidine possesses antiviral activity against SARS-CoV-2(IC90 = 0.88 nM). Aplidine is a potent anti-cancer agent by targeting eukaryotic translation elongation factor 1 Alpha 2(EEF1A2, Kd = 80 nM). | |||
T4593 | ISOPIMPINELLIN | 5,8-Dimethoxypsoralen,4,9-Dimethoxypsoralen | Antiviral , DNA/RNA Synthesis , Parasite |
Isopimpinellin (4,9-Dimethoxypsoralen) is a natural product isolated from the roots of Pimpinella saxifrage with antiviral and antileishmanial activity. | |||
T13791 | N2-methylguanine | DNA/RNA Synthesis , Endogenous Metabolite , Antibacterial | |
N2-methylguanine (N2-methylguanine) is an endogenous methylated nucleoside found in human fluids and a modified nucleoside. | |||
T0064 | Adenine | Vitamin B4,6-Aminopurine | DNA/RNA Synthesis , Endogenous Metabolite , AChR |
Adenine (6-Aminopurine), a purine derivative, is a nucleobase with various roles in biochemistry including cellular respiration, in the form of both the energy-rich ATP and NAD and FAD, and protein synthesis, as a chemic... | |||
TWP2911 | Thymidine | 5-Methyldeoxyuridine,Deoxyribothymidine,DThyd,NSC 21548,Thymidin | Others , DNA/RNA Synthesis , Endogenous Metabolite |
1. Thymidine (DThyd) overload due to Thymidine phosphorylase deficiency, and mitochondrial toxicity caused by antiviral Thymidine analogues. | |||
T6116 | Bleomycin Sulfate | Blenoxane,NSC125066 | DNA/RNA Synthesis , Antibiotic |
Bleomycin Sulfate (Blenoxane) is a glycopeptide antibiotic, an inhibitor of DNA synthesis. Bleomycin Sulfate causes DNA strand breaks but not RNA strand breaks. Bleomycin Sulfate has antitumor activity. | |||
T7004 | Tubercidin | Sparsomycin A,7-Deazaadenosine | Influenza Virus , DNA/RNA Synthesis , Antibacterial , Antibiotic |
Tubercidin (Sparsomycin A), an adenosine analogue, is a nucleoside antibiotic. It is incorporated into DNA and inhibits polymerases, thereby inhibiting DNA replication and RNA and protein synthesis. This agent also exhib... | |||
T6758 | Anisomycin | Flagecidin,NSC 76712,Wuningmeisu C | Apoptosis , DNA/RNA Synthesis , Antibacterial , Antibiotic , JNK |
Anisomycin (NSC-76712) is an antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system. | |||
T40426 | Cytidine 5'-diphosphate trisodium salt | CDP | Others |
Cytidine 5'-diphosphate trisodium salt (CDP) can produce Cytidine triphosphate for synthesis of DNA and RNA through the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosp... | |||
TN1097 | β-Boswellic acid | Beta-boswellic acid | Lipoxygenase , DNA/RNA Synthesis |
β-Boswellic acid (Beta-boswellic acid) and its derivatives (the major constituents of Boswellin) have anti-carcinogenic, anti-tumor, and anti-hyperlipidemic activities. | |||
T7174 | Urolithin A | Apoptosis , Reactive Oxygen Species , DNA/RNA Synthesis , Endogenous Metabolite , Autophagy , Drug Metabolite | |
Urolithin A is a secondary metabolite of ellagic acid, a polyphenolic antioxidant, that has antiproliferative, anti-inflammatory, and anti-oxidant properties. | |||
T3343 | 5-methoxyflavone | 5-methoxy-2-phenylchromen-4-one | DNA/RNA Synthesis |
5-methoxyflavone (5-methoxy-2-phenylchromen-4-one) is a naturally occurring, low molecular weight flavonoids compound that associated with a wide wariety of biological activities. | |||
TN2111 | Prunin | Naringenin 7-0-glucoside | Phosphatase , Anti-infection , Virus Protease |
Prunin (Naringenin 7-0-glucoside) possesses anti-diabetic, and anti-abacterial properties, it can inhibit protein tyrosine phosphatase 1B (PTP1B) and stimulate glucose uptake in insulin-resistant HepG2 cells; it also can... | |||
T38427 | DUTP trisodium | 2'-Deoxyuridine-5'-triphosphate trisodium salt,Deoxyuridine triphosphate | DNA/RNA Synthesis |
dUTP trisodium (Deoxyuridine triphosphate) is a deoxyuridine phosphate having a triphosphate group at the 5'-position and can be used for PCR. | |||
T1335 | Mycophenolic acid | Mycophenolate,RS-61443 | Apoptosis , Dehydrogenase , Endogenous Metabolite , Antibacterial , Antibiotic , UGT , Antifungal |
Mycophenolic acid (Mycophenolate) is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity. | |||
T0746 | Orotic acid | Vitamin B13,6-Carboxyuracil | Nucleoside Antimetabolite/Analog , Dehydrogenase , Endogenous Metabolite |
Orotic acid (Vitamin B13) is an intermediate product in pyrimidine metabolism. | |||
T6567 | Levofloxacin | Levaquin,Cravit,Tavanic,Fluoroquinolone,(-)-Ofloxacin | Topoisomerase , Antibacterial , Antibiotic |
Levofloxacin (Fluoroquinolone) is a broad-spectrum antibiotic topoisomerase II and topoisomerase IV inhibitor, used to treat respiratory, urinary tract, gastrointestinal, and abdominal infections. | |||
T0062 | Folic acid | Folate,Vitamin B9,Pteroylglutamic acid,Vitamin M,Folacin | DNA/RNA Synthesis , Endogenous Metabolite |
Folic acid (Vitamin B9)(Vitamin M; Vitamin B9) is indispensable for the production and maintenance of new cells, for DNA/RNA synthesis. | |||
T8186 | Xanthosine 5'-monophosphate sodium salt | XMP,L-XMP Sodium | Others |
Xanthosine 5'-monophosphate sodium salt (L-XMP Sodium) is an intermediate in purine metabolism. | |||
T6225 | Adenine hydrochloride | Adenine HCl,6-Aminopurine hydrochloride | DNA/RNA Synthesis , Endogenous Metabolite |
Adenine hydrochloride (6-Aminopurine hydrochloride) is a hydrochloride salt form of adenine which is a nucleobase with a variety of roles in biochemistry. | |||
T1591L | Cytidine | Cytosine-1-β-D-ribofuranoside,Cytosine β-D-riboside | Nucleoside Antimetabolite/Analog , Endogenous Metabolite |
Cytidine (Cytosine-1-β-D-ribofuranoside) is a pyrimidine nucleoside comprised of a cytosine bound to ribose via a beta-N1-glycosidic bond. Cytidine is a precursor for uridine. Both cytidine and uridine are utilized in RN... | |||
T6369 | Adenine hemisulfate | Diadenine sulphate,Adenine sulfate,Adeninsulfat | DNA/RNA Synthesis , Endogenous Metabolite |
Adenine hemisulfate (Diadenine sulphate) is a sulfate salt form of adenine which is a purine derivative and a nucleobase with a variety of roles in biochemistry. | |||
T0974 | Novobiocin Sodium | Albamycinsodium,Cathomycin,Albamycin | Potassium Channel , DNA gyrase , Topoisomerase , Antibacterial , Antibiotic , ABC , Autophagy |
Novobiocin Sodium (Albamycinsodium) binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound derived from Streptomyces niveus. It has a chemical structure sim... | |||
T20945 | 2,4-D | Hedonal,Macondray,2,4-D acid,Chloroxone | DNA/RNA Synthesis |
2,4-Dichlorophenoxyacetic acid (Hedonal) is a synthetic auxin used as a plant growth regulator and also used as a supplement in plant cell culture media. It is an active ingredient in herbicides used to disrupts the acti... | |||
T1507 | Streptozocin | STZ,Streptozotocin,NSC-85998,U 9889 | DNA Alkylator/Crosslinker , DNA Alkylation , DNA/RNA Synthesis , Antibacterial , Antibiotic , Autophagy |
Streptozocin (NSC-85998) is an antibiotic that induces DNA methylation. Streptozocin is toxic to insulin-producing pancreatic islet B-cells and is commonly used in the construction of animal models of type 1 diabetes. Th... | |||
T3271 | Orotic acid zinc | Orotic acid zinc salt dihydrate,Zinc Orotate | Nucleoside Antimetabolite/Analog , Others , Endogenous Metabolite |
Orotic acid zinc (Zinc Orotate) salt dihydrate is an intermediate product in pyrimidine synthesis. | |||
T3376 | Cynaroside | Luteoloside,Luteolin 7-β-D-Glucopyranoside,Luteolin 7-O-Glucoside,Luteolin 7-O-β-D-glucoside,Luteolin 7-glucoside | Others , Influenza Virus , DNA/RNA Synthesis |
Cynaroside (Luteolin 7-O-Glucoside) is a flavone, a flavonoid-like chemical compound. It has an anti-oxidant effect, inhibiting lipid and protein oxidation. | |||
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カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-06071 | SARS-CoV-2 RNA-dependent RNA polymerase/RDRP Protein (His) | SARS-CoV-2 | Baculovirus Insect Cells |
SARS-CoV-2 RNA-dependent RNA polymerase/RDRP Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 108.3 kDa and the accession number is YP_009725307.1. | |||
TMPY-03983 | CIRBP Protein, Human, Recombinant (His) | Human | E. coli |
CIRBP, also known as cold-inducible RNA-binding protein, plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. CIRBP responds to a wide array of cellular ... | |||
TMPH-03193 | Alba Protein, Pyrococcus furiosus, Recombinant (His & SUMO) | Pyrococcus furiosus | E. coli |
Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DN... | |||
TMPH-01110 | CIRBP Protein, Human, Recombinant (GST) | Human | E. coli |
CIRBP Protein, Human, Recombinant (GST) is expressed in E. coli. | |||
TMPH-00533 | T7 RNA polymerase Protein, Enterobacteria phage T7, Recombinant (His & Myc) | Escherichia phage T7 | E. coli |
Highly processive DNA-dependent RNA polymerase that catalyzes the transcription of class II and class III viral genes. Recognizes a specific promoter sequence and enters first into an 'abortive phase' where very short tr... | |||
TMPH-02587 | CIRBP Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Promotes assembly of stress granules (SGs), when overexpres... | |||
TMPH-01900 | DDX5 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
DDX5 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 74.1 kDa and the accession number is P17844. | |||
TMPH-01248 | ADAR Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translatio... | |||
TMPH-00980 | DHX33 Protein, Human, Recombinant (His) | Human | E. coli |
DHX33 Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPH-01249 | ADAR Protein, Human, Recombinant (GST) | Human | E. coli |
ADAR Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 47.2 kDa and the accession number is P55265. | |||
TMPH-02133 | DDX39B Protein, Human, Recombinant (GST) | Human | E. coli |
Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mR... | |||
TMPH-00974 | DHX9 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
DHX9 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPH-01902 | DDX60 Protein, Human, Recombinant (His) | Human | E. coli |
Positively regulates DDX58/RIG-I- and IFIH1/MDA5-dependent type I interferon and interferon inducible gene expression in response to viral infection. Binds ssRNA, dsRNA and dsDNA and can promote the binding of DDX58/RIG-... | |||
TMPY-03344 | LSM3 Protein, Human, Recombinant (His) | Human | E. coli |
LSM3 (LSM3 Homolog, U6 Small Nuclear RNA And MRNA Degradation Associated) is a Protein Coding gene. LSM3 is a member of the snRNP Sm proteins family. It plays role in pre-mRNA splicing as a component of the U4/U6-U5 tri-... | |||
TMPH-00979 | DDX3Y Protein, Human, Recombinant (His & Myc) | Human | Baculovirus Insect Cells |
DDX3Y Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus. | |||
TMPH-00976 | DDX19A Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
DDX19A Protein, Human, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPH-02884 | CTDP1 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Processively dephosphorylates 'Ser-2' and 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit. This promotes the activity of RNA polymerase II. Plays a role in the exit... | |||
TMPH-00975 | DDX1 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
DDX1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPH-00973 | DHX36 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
DHX36 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.2 kDa and the accession number is Q9H2U1. | |||
TMPH-01556 | EIF2AK2 Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
EIF2AK2 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 64.0 kDa and the accession number is P19525. | |||
TMPH-01899 | ALKBH5 Protein, Human, Recombinant (His) | Human | E. coli |
ALKBH5 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 48.2 kDa and the accession number is Q6P6C2. | |||
TMPH-01310 | EIF3G Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
EIF3G Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 51.5 kDa and the accession number is O75821. | |||
TMPH-01901 | DDX53 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
N/A. DDX53 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 76.2 kDa and the accession number is Q86TM3. | |||
TMPH-00978 | DDX3X Protein, Human, Recombinant (His & Myc) | Human | Baculovirus Insect Cells |
DDX3X Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 77 kDa and the accession number is O00571. | |||
TMPH-00977 | DDX3X Protein, Human, Recombinant (B2M & His) | Human | E. coli |
DDX3X Protein, Human, Recombinant (B2M & His) is expressed in E. coli. | |||
TMPH-01036 | Caprin-1/CAPRIN1 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Binds directly and selectively to MYC and CCND2 RNAs... | |||
TMPH-02487 | CHRNA1 Protein, Mouse, Recombinant (His) | Mouse | P. pastoris (Yeast) |
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. CHRNA1 Protein, Mouse, Recombi... | |||
TMPJ-00574 | RNASE3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Ribonuclease 3 (RNASE3) is a basic protein that is localized to the eosinophil primary matrix and belongs to the pancreatic ribonuclease family. RNASE3 is released during degranulation of eosinophils. RNASE3 possesses a ... | |||
TMPJ-01258 | RNASE6 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Ribonuclease K6 (RNASE6) is a secreted protein that belongs to the pancreatic ribonuclease family. Human RNASE6 is synthesized as a 150 amino acid precursor that contains a 23 amino acid signal sequence, and a 127 amino ... | |||
TMPY-02441 | Alanyl-tRNA synthetase Protein, Mouse, Recombinant (His) | Mouse | Baculovirus Insect Cells |
alanyl-tRNA synthetase Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 108.3 kDa and the accession number is Q8BGQ7. | |||
TMPH-00313 | TRNA (guanine-N(7)-)-methyltransferase Protein, Brugia malayi, Recombinant (His) | Brugia malayi | E. coli |
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. tRNA (guanine-N(7)-)-methyltransferase Protein, Brugia malayi, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. ... | |||
TMPH-00847 | 2-5A-dependent Rnase Protein, Human, Recombinant (Myc) | Human | E. coli |
2-5A-dependent Rnase Protein, Human, Recombinant (Myc) is expressed in E. coli expression system with C-Myc tag. The predicted molecular weight is 85.1 kDa and the accession number is Q05823. | |||
TMPY-04321 | CHRNA5 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Genetic variation in the cluster on chromosome 15, encoding the nicotinic acetylcholine receptor subunits (CHRNA5-CHRNA3-CHRNB4), has shown strong associations with tobacco consumption and an additional risk increase in ... | |||
TMPH-03621 | CHRNA1 Protein, Tetronarce californica, Recombinant (His) | Tetronarce californica | HEK293 Cells |
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. CHRNA1 Protein, Tetronarce cal... | |||
TMPH-03620 | CHRNA1 Protein, Tetronarce californica, Recombinant (E. coli, His) | Torpedo californica | E. coli |
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. CHRNA1 Protein, Tetronarce cal... | |||
TMPY-02769 | RNASET2 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
RNASET2 (ribonuclease T2) is an enzyme that belongs to the RNase T2 family. It is highly expressed in the temporal lobe and fetal brain. RNASET2 gene is a novel member of the Rh/T2/S-glycoprotein class of extracellular r... | |||
TMPH-00871 | CHRNA1 Protein, Human, Recombinant (His) | Human | E. coli |
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. CHRNA1 Protein, Human, Recombi... | |||
TMPH-01762 | CHRNA3 Protein, Human, Recombinant (His & Myc & SUMO) | Human | E. coli |
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. CHRNA3 Protein, Human, Recombi... | |||
TMPH-01457 | Human herpesvirus 6B (HHV-6 variant B) (strain Z29) mRNA export factor ICP27 homolog (His & Myc) | HHV-6B | E. coli |
Immediate early (EI) protein that plays many roles during productive infection including regulation of viral gene expression and nuclear export of intronless viral RNAs. Human herpesvirus 6B (HHV-6 variant B) (strain Z29... | |||
TMPH-02486 | CHRNA1 Protein, Mouse, Recombinant (E. coli, His) | Mouse | E. coli |
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. CHRNA1 Protein, Mouse, Recombi... | |||
TMPY-04946 | Alt a 1 Protein, Alternaria alternate, Recombinant | Alternaria alternate | E. coli |
Alt a 1 Protein, Alternaria alternate, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 14.6 kDa and the accession number is P79085. | |||
TMPH-01779 | RNASE2 Protein, Human, Recombinant (His) | Human | E. coli |
This is a non-secretory ribonuclease. It is a pyrimidine specific nuclease with a slight preference for U. Cytotoxin and helminthotoxin. Selectively chemotactic for dendritic cells. Possesses a wide variety of biological... | |||
TMPY-05305 | Alanyl-tRNA synthetase Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
alanyl-tRNA synthetase Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 109.2 kDa and the accession number is P49588. | |||
TMPY-04870 | Zika virus (ZIKV) (strain Zika SPH2015) ZIKV-NS1 protein (His) | ZIKV | HEK293 Cells |
Zika virus NS1 antigen is one of seven non-structural proteins. NS1 is involved in RNA replication. The possible effects of NS1 on hosts include: localizes to host cell surface and secreted extracellularly, modulates sig... | |||
TMPY-05822 | Hepatitis B Virus (HBV)(ayw/France/Tiollais/1979) Capsid protein (His) | HBV-D | E. coli |
Hepatitis B virus (HBV) capsid assembly is a critical step in the propagation of the virus and is mediated by the core protein. The first cytoplasmic step in the formation of an infectious HBV virion is the formation of ... | |||
TMPK-00265 | SARS-COV-2 Nucleocapsid Protein (His & Avi), Biotinylated | SARS-CoV-2 | E. coli |
Nucleocapsid protein (N) is the major viral structural component; its main function is to protect and encapsidate the viral RNA forming viral RNP complex. It is encoded by the S segment vRNA and is abundantly expressed i... | |||
TMPY-02219 | Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His) | H1N1 | E. coli |
The NS1 Influenza protein is created by the internal protein-encoding, linear negative-sense, single-stranded RNA, NS gene segment and which also codes for the nuclear export protein or NEP, formerly referred to as the N... | |||
TMPY-05024 | Zika virus (ZIKV) (strain Zika SPH2015) ZIKV-NS5 protein (His) | ZIKV | Baculovirus Insect Cells |
Zika virus NS5 is involved in methytransferase and RNA guanylytransferase activities and capping and synthesis of RNA. And, NS5 is also an RNA-dependent RNA polymerase. | |||
TMPY-05749 | SARS-CoV-2 NSP8 Protein (Avi) | SARS-CoV-2 | E. coli |
NSP8 is a nonstructural protein of coronavirus. NSP8 acts as a primase in RNA synthesis. NSP8 and NSP7 are essential co-factors of NSP12 (the catalytic subunit with RNA-dependent RNA polymerase activity) that can remarka... | |||
TMPH-01674 | Human metapneumovirus (strain CAN97-83) Nucleoprotein/NP Protein (His & Myc) | HMPV | E. coli |
Encapsidates the viral RNA genome by forming a left-handed helical nucleocapsid that protects the RNA from nucleases. RNA replication depends on the availability of soluble nucleoprotein. The encapsidated genomic RNA is ... | |||
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Well-chosen 953 compounds related to epigenetic regulation for research in epigenetics, high throughput screening (HTS) and high content screening (HCS) for new drugs; | |||
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A unique collection of 677 cell cycle related compounds for high throughput screening (HTS) and high content screening (HCS); | |||
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A unique collection of 514 flavonoids can be used for high throughput and high content screening; | |||
L5500 | Toxic Compound Library | 262 compounds | |
A unique collection of 262 toxic substances for high throughput screening (HTS) and high content screening (HCS); | |||
L1380 | Transcription Factor-Targeted Compound Library | 695 compounds | |
Well-chosen 695 compounds with unique structures targeting transcription factor; | |||
L1710 | Anti-COVID-19 Compound Library | 1133 compounds | |
A unique collection of 1133 compounds with confirmed anti-SARS-CoV-2 activity or potential activity and part of them are broad-spectrum antiviral agents; | |||
L3800 | NF-κB Signaling Compound Library | 729 compounds | |
A unique collection of 729 compounds targeting NF-κB signaling for high throughput screening and high content screening; | |||
L9420 | Exosome Compound Library | 76 compounds | |
76 exosome-related compounds that can be used for high-throughput and high-content screening. |