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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T9111 | 8-Azaadenosine | Adenosine deaminase | |
8-Azaadenosine, a powerful ADAR1 (ADAR1) and A-to-I editing inhibitor, effectively blocks RNA editing and suppresses proliferation, 3D growth, invasion, and migration in thyroid cancer cells. | |||
T12073 | ML-109 | TSH Receptor | |
ML-109 is a potent agonist of thyroid stimulating hormone receptor (TSHR) (EC50 of 40 nM) | |||
T5360 | Eprotirome | KB2115 | Thyroid hormone receptor(THR) |
Eprotirome (KB2115), a synthetic thyroid hormone mimetic, is a thyroid hormone receptor agonist. | |||
T8843 | APS6-45 | MAPK , Ras | |
APS6-45 inhibits RAS/MAPK signaling and exhibits anti-tumor activity. | |||
T2282 | RPI-1 | Others , Phospholipase , c-Met/HGFR , c-RET | |
RPI-1 is a competitive, potent ATP-dependent Ret kinase inhibitor. | |||
T40548 | NH-3 | Thyroid hormone receptor(THR) | |
NH-3 is a potent orally active thyroid hormone receptor (THR) antagonist which exhibits reversible behavior, demonstrated by an IC 50 of 55 nM. Derived from the selective thyromi-metic GC-1, NH-3 effectively inhibits the... | |||
T1604 | Tiratricol | 3,3',5-Triiodothyroacetic acid | Thyroid hormone receptor(THR) |
Tiratricol (3,3',5-Triiodothyroacetic acid) is a metabolite of T3 and T4 thyroid hormones; promoted for hyperlipidemia, localized lipodystrophy, and obesity. Tiratricol has been used in trials studying the treatment of A... | |||
T12192 | NCGC00229600 | Others , TSH Receptor | |
NCGC00229600 is an allosteric inverse thyrotropin receptor (TSHR) agonist. NCGC00229600 inhibits both TSH and stimulating antibody activation of TSHRs endogenously and can be used in Graves' disease studies. | |||
T15012 | Crolibulin | EPC2407 | Microtubule Associated |
Crolibulin (EPC2407) is an inhibitor of small molecule tubulin polymerization. | |||
T13072 | Taltirelin acetate | TA-0910 acetate | Thyroid hormone receptor(THR) |
Taltirelin acetate (TA-0910 acetate) is a superagonist at thyrotropin-releasing hormone receptor (TRH-R)(IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ concentration (Ca2+ release)). | |||
T3595 | Resmetirom | VIA-3196,MGL3196 | Thyroid hormone receptor(THR) |
Resmetirom (VIA-3196) is a highly selective thyroid hormone receptor β (THR-β) agonist. | |||
T5383 | D3-βArr | NCGC00379308 | TSH Receptor |
D3-βArr (NCGC00379308) is a positive allosteric modulator for thyrotropin receptor (TSHR), which initiates translocation of β-Arr 1 (EC50: 11.6 μM) by direct TSHR activation. | |||
T1669 | Liothyronine sodium | 3,3',5-Triiodo-L-thyronine sodium,Triostat,T3 Sodium salt,Sodium L-3,3',5-triiodothyronine,Cytomel | Thyroid hormone receptor(THR) |
Liothyronine Sodium is the sodium salt form of liothyronine, a synthetic form of the levorotatory isomer of the naturally occurring thyroid hormone triiodothyronine (T3). Liothyronine sodium (3,3',5-Triiodo-L-thyronine s... | |||
T13492 | 3,5-Diiodothyropropionic acid | C082182,Ditpa cpd | Thyroid hormone receptor(THR) |
3,5-Diiodothyropropionic acid (C082182) is a thyroid hormone analog. It induces α-myosin heavy chain mRNA expression, binds to thyroid hormone receptor (Ka: 2.40/M and 4.06/M for TRα1 and TRβ1). | |||
T5313 | Sobetirome | IACS-010759,QRX-431 | Thyroid hormone receptor(THR) |
Sobetirome (IACS-010759) is a selective agonist of thyroid hormone receptor β (TRβ) and binds selectively to TRβ-1 (EC50: 0.16 μM). | |||
T7578 | REVERSE T3 | 3,3',5'-triiodo-L-thyronine | Thyroid hormone receptor(THR) |
Reverse T3 (3,3',5'-triiodo-L-thyronine) inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes. | |||
TP1022 | Protirelin Acetate | TSH-RF Acetate,TRH Acetate,TRF Acetate | Thyroid hormone receptor(THR) , Endogenous Metabolite |
Protirelin Acetate (TRH Acetate) is a thyrotropin-releasing hormone, stimulating the release of thyrotropin and prolactin from the anterior pituitary. | |||
T21505 | Suberoyl bis-hydroxamic acid | SBHA,Suberohydroxamic acid | Apoptosis , HDAC |
Suberoyl bis-hydroxamic acid (SBHA) is a Histone deacetylase (HDAC) inhibitor. HDAC is required for transcriptional modulation, cell cycle regulation and development. It is an enzyme that deacetylates lysine residues on ... | |||
T22355 | L-Thyroxine sodium | LT4 sodium,Levothyroxine sodium,L-T4 sodium | Thyroid hormone receptor(THR) |
L-Thyroxine sodium (LT4 sodium), the major hormone derived from the thyroid gland, is the agonist of Thyroid hormone receptor alpha and beta. | |||
T1826 | PI3K-IN-1 | Voxtalisib Analogue,Voxtalisib (SAR245409, XL765) Analogue,XL765,SAR245409 | DNA-PK , PI3K |
PI3K-IN-1 (Voxtalisib Analogue) is a dual inhibitor of mTOR/PI3K, mostly for p110γ , also inhibits DNA-PK and mTOR. | |||
T7590 | Taltirelin | TA-0910 | Thyroid hormone receptor(THR) |
Taltirelin (TA-0910) is at thyrotropin-releasing hormone receptor (TRH-R) superagonist (IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ concentration (Ca2+ release))[1]. | |||
T15699 | L-Thyroxine sodium salt pentahydrate | Sodium levothyroxine pentahydrate,Levothyroxine | Thyroid hormone receptor(THR) |
L-Thyroxine sodium salt pentahydrate, also known as Levothyroxine, is a synthetic hormone utilized in the study of hypothyroidism. It is biologically activated into Triiodothyronine (T3) from its original form, L-Thyroxi... | |||
T21535 | Parathyroid Hormone (1-34), bovine | Thyroid hormone receptor(THR) | |
Parathyroid Hormone (1-34), bovine is a parathyroid hormone (PTH) receptor agonist that is part of the parathyroid hormone family. Parathyroid Hormone (1-34), bovine is used to study osteoporosis and hypoparathyroidism. | |||
T36767 | Parathyroid Hormone (1-13) (trifluoroacetate salt) | ||
Parathyroid hormone (PTH) (1-13) is an N-terminal fragment of PTH (1-34) . In vivo, PTH (1-13) (0.003-1 μmol/kg) increases mean arterial pressure (MAP) in anesthetized rats. | |||
TP2283 | Parathyroid hormone (7-34) [Homo sapiens]/[Macaca fascicularis] | Others | |
parathyroid hormone (7-34) [Homo sapiens] [Macaca fascicularis] is a peptide with the sequence H2N-LMHNLGKHLNSMERVEWLRKKLQDVHNF-OH, MW= 3474.03. Parathyroid hormone (PTH) is secreted by the chief cells of the parathyroid... | |||
T75867 | Parathyroid Hormone (1-34), bovine TFA | ||
Parathyroid Hormone (1-34), bovine TFA, a potent agonist of the parathyroid hormone (PTH) receptor, elevates calcium and inorganic phosphate levels in vivo. This compound is employed in osteoporosis research [1]. | |||
T76061 | Parathyroid hormone (1-34) (rat) acetate | ||
Parathyroid hormone (1-34) (rat) (acetate) is a parathyroid hormone variant that enhances the structure of both cortical and cancellous bones. It is utilized in osteoporosis research [1] [2]. | |||
TP1964 | Parathyroid hormone (1-34) (rat) | ||
Parathyroid hormone (PTH) receptor agonist. Increases serum PTH levels and bone mass in rats. | |||
T76084 | Parathyroid Hormone (1-34), human, biotinylated | ||
Parathyroid Hormone (1-34), human, biotinylated serves as a probe targeting the parathyroid hormone receptor. It is utilized in the analysis of interactions between parathyroid hormone and its receptors within living cel... | |||
T73692 | Parathyroid hormone | ||
Parathyroid hormone (PTH), an 84-amino acid circulating hormone synthesized in the parathyroid glands, primarily regulates bone and kidney functions to maintain extracellular calcium levels within normal ranges. It is al... | |||
T2588 | Ivacaftor | Ivacaftor (VX-770),VX-770 | CFTR , Autophagy |
Ivacaftor (VX-770) (VX-770) is a potentiator of CFTR targeting G551D-CFTR (EC50: 100 nM) and F508del-CFTR (EC50: 25 nM) in Fisher rat thyroid cells, respectively. | |||
T16756 | Risarestat | CT 112 | Reductase |
Risarestat (CT-112) is a potent aldose reductase inhibitor and thyroid hormone receptor (TR) antagonist for the treatment of hypoglycemia. | |||
T8672 | 2,2-BIS(2-HYDROXY-5-BIPHENYLYL)PROPANE | BisOPP-A | Thyroid hormone receptor(THR) |
2,2-BIS(2-HYDROXY-5-BIPHENYLYL)PROPANE is targets the thyroid stimulating hormone receptor (human) | |||
T23673 | AH-3960 | AH3960 | Thyroid hormone receptor(THR) |
AH-3960 is an thyroid hormone receptor-1 (PTHR1) agonist. | |||
T27454 | GSK2008607 | Raf | |
GSK2008607 is a potent B-RafV600E inhibitor with anticancer activity and can be used to study breast, colorectal, melanoma, thyroid, and ovarian cancers. | |||
T1309 | Propylthiouracil | Pseudocapsaicin,NSC 6498,NSC 70461,6-n-Propylthiouracil,6-Propyl-2-thiouracil | Thyroid hormone receptor(THR) |
Propylthiouracil (6-n-Propylthiouracil) is a thyroid peroxidase inhibitor and also a 5' -deiodinase inhibitor. | |||
T0357 | Potassium iodide | Tyrosinase | |
Potassium iodide is used as the treatment of overactive thyroid and as protection of the thyroid gland from the influences of radiation from swallowed or inhaled radioactive iodine. It may be used after accidental exposu... | |||
TP1028L | Calcitonin eel acetate | Calcitonin eel acetate (57014-02-5 Free base),Thyrocalcitonin eel | Others |
Calcitonin eel acetate (Calcitonin eel acetate (57014-02-5 Free base)) is the regulation of calcium homeostasis thyroid hormone peptide. | |||
T7407 | Thyrotropin-Releasing Hormone (TRH), Free Acid | TRH-OH | Others |
Thyrotropin-Releasing Hormone (TRH), Free Acid (TRH-OH) (TRH-OH) causes a variety of thyroidal and non-thyroidal effects, the best known being the feedback regulation of thyroid hormone levels. | |||
T19561 | Simetryn | Others | |
Simetryn is a rice paddy herbicide and acts as a chemical stressor retarding tadpole growth and development without disrupting thyroid functions, even at 1/100 of the 96-h LC50 value. | |||
T0495 | Aminothiazole | 2-Aminothiazole,2-Thiazolylamine | Virus Protease , Antibacterial , Antibiotic , Antifungal |
Aminothiazole (2-Aminothiazole), a thyroid inhibitor, displays antibacterial activity. | |||
T0304 | Methylthiouracil | NSC-193526,NSC-9378,MTU | ERK , Antiviral , TNF , NF-κB , Interleukin |
Methylthiouracil (NSC-193526) is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and it is used to treat hyperthyroidism. | |||
T9901A-004 | Labetuzumab | IMMU-14,hMN-14,IMMU-100 | |
Labetuzumab is a humanized anti-carcinoembryonic antigen (CEA) monoclonal antibody with anticancer activity that inhibits tumor growth and is used in the study of thyroid and colorectal cancer (CRC). | |||
T8628 | 2,4,6-Triiodophenol | Others | |
2,4,6-Triiodophenol is used as an iodinated disinfection by product formed during chlorination of sewage effluents. It is also used as a potent thyroid disrupting chemical and to investigate deiodinase | |||
T0952 | Carbimazole | Athyromazole,Carbimazol,Neomercazole | Thyroid hormone receptor(THR) |
Carbimazole (Athyromazole) is an Imidazolium thyroid antagonist, which is rapidly transformed into MMI in vivo and can be converted into methidazole in vitro, and can be used in the study of Graves' disease. | |||
T0312 | Toluidine Blue | Blutene chloride | Others |
Toluidine Blue (Blutene chloride), a phenothiazine, is used as a biological stain, a hemostatic, and a dye for silk and wool. Blutene chloride is also used as a diagnostic aid for gastric neoplasms and oral, and used in ... | |||
T77075 | Spartalizumab | PDR001 | PD-1/PD-L1 |
Spartalizumab (PDR001) is a humanized immunoglobulin 4 monoclonal antibody that selectively binds to PD-1 at low concentrations and shows high activity. Spartalizumab blocks the interaction with PD-L1 and PD-L2, and can ... | |||
T76727 | Teprotumumab | R 1507,HZN 001 | TSH Receptor , IGF-1R |
Teprotumumab is a human monoclonal antibody that blocks the IGF-1 receptor (IGF-1R). Teprotumumab binds to the extracellular α-subunit domain ligand of IGF-1R. Teprotumumab inhibits TSH and IGF-1 action in fibrocytes. Te... | |||
T2595 | Lumacaftor | VX-809,VRT 826809 | CFTR , Autophagy |
Lumacaftor (VRT 826809) is a CFTR modulator that corrects the folding and trafficking of CFTR protein. It enhances F508del-CFTR protein maturation in FRT cells (EC50: 100 nM). | |||
T36493 | CMLD-2 | Apoptosis , HuR | |
CMLD-2 is an inhibitor of HuR-ARE interaction (Ki: 350 nM) that competitively binds HuR protein and disrupts its interaction with adenine element-rich (ARE) mRNA targets.CMLD-2 induces apoptosis and exhibits antitumor ef... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T1653 | Liothyronine | Tresitope,O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine,Triiodothyronine,L-3,3',5-Triiodothyronine,3,3',5-Triiodo-L-thyronine,Lyothyronine | Thyroid hormone receptor(THR) , Endogenous Metabolite |
Liothyronine (Tresitope) is an active form of thyroid hormone, binding to β1 thyroid hormone receptor (TRβ1), and activates its activity. | |||
T5568 | H-Tyr(3-I)-OH | 3-Iodo-L-tyrosine | Endogenous Metabolite |
H-Tyr(3-I)-OH (3-Iodo-L-tyrosine) is an inhibitor of tyrosine hydroxylase (Ki = 0.39 M) and an intermediate in the synthesis of thyroid hormones | |||
T0864 | L-Thyroxine | Levothyroxine,NSC 36397,T4 | Thyroid hormone receptor(THR) , Endogenous Metabolite |
L-Thyroxine (NSC 36397) is the major hormone derived from the thyroid gland. L-Thyroxine (NSC 36397) is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in... | |||
T2988 | (-)-Epigallocatechin Gallate | Epigallocatechol Gallate,EGCG | Ferroptosis , Reactive Oxygen Species , HIV Protease , Mitochondrial Metabolism , Endogenous Metabolite , Autophagy |
(-)-Epigallocatechin Gallate (EGCG) is an antioxidant polyphenol flavonoid that inhibits telomerase and DNA methyltransferase. (-)-Epigallocatechin Gallate (EGCG) blocks the activation of EGF receptors and HER-2 receptor... | |||
T6956 | Protirelin | Lopremone,pGlu-His-Pro-NH2,Synthetic thyrotropin-releasing hormone,Thyroliberin,TRH,TRF | Thyroid hormone receptor(THR) , Endogenous Metabolite |
Protirelin (Thyroliberin) is a tripeptide that stimulates the release of thyrotropin and prolactin. | |||
T16442 | PCO371 | 2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl- | Thyroid hormone receptor(THR) |
PCO371 (2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-) is an orally active full agonist of parathyroid hormon... | |||
T2760 | (S)-2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid dihydrate | Iodogorgoic acid,apothyrin,jodgorgon,3,5-Diiodotyrosine Dihydrate | Others , Endogenous Metabolite |
(S)-2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid dihydrate (jodgorgon) is a product from the iodination of MONOIODOTYROSINE. In the biosynthesis of thyroid hormones, diiodotyrosine residues are coupled with other... | |||
T3665 | Tectoridin | Shekanin | Estrogen Receptor/ERR , Reductase |
Tectoridin (Shekanin) possesses an estrogenic and thyroid hormone-like agent by activating estrogen and thyroid hormone receptors. Tectoridin has anti-oxidant, anti-inflammatory and hypoglycemic activities; Tectoridin an... | |||
TN6798 | Progoitrin | Others | |
Progoitrin is a biochemical from the glucosinolate family that is found in some food, which is inactive but after ingestion is converted to goitrin. Goitrin decreases the thyroid hormone production. Apart from goitrin, p... | |||
T39836 | Monoethyl phthalate | ||
Monoethyl phthalate is a metabolite of diethyl phthalate, serving as a urinary biomarker for phthalate exposure, and indicating potential risks of thyroid cancer and benign nodules. | |||
T73465 | Goitrin | L-5-Vinyl-2-thiooxazolidone,(S)-Goitrin,(S)-Goitrin ; L-5-Vinyl-2-thiooxazolidone | |
Goitrin ((S)-Goitrin), formed through glucosinolate-myrosinase reactions, serves as a potent inhibitor of thyroid peroxidase, thereby hindering the thyroid's utilization of iodine. Additionally, it demonstrates anti-infl... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-02779 | Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His) | Human | Baculovirus Insect Cells |
Thyroid peroxidase is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It contains 1 EGF-like domain and 1 Sushi (CCP/SCR) domain. Thyroid Peroxidase represents one of the main autoant... | |||
TMPK-00874 | Thyroid Peroxidase Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Thyroid peroxidase, also called thyroperoxidase (TPO) or iodide peroxidase that encodes a 933 amino-acid residue (aa) molecule with a single membrane-spanning region. Thyroid peroxidase plays a key role in thyroid hormon... | |||
TMPY-04127 | CIp4 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
CIp4 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 64 kDa and the accession number is Q15642-2. | |||
TMPY-06821 | THRB Protein, Human, Recombinant (His) | Human | E. coli |
Thyroid hormone receptor beta (THRB), also known as TRbeta and NR1A2, belongs to the nuclear hormone receptor family. Featuring an N-terminal transactivation domain, a central DNA-binding domain, and a hormone/ligand-bin... | |||
TMPY-04853 | TSHR Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Thyroid-stimulating hormone (TSH) is secreted by the pituitary gland and promotes thyroid growth and function, with increased TSH levels typically associated with hypothyroidism. Immunohistochemical analysis revealed pre... | |||
TMPY-02287 | Ku70 & Ku80 Heterodimer Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
X-ray repair cross-complementing protein 5, also known as 86 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 2, ATP-dependent DNA helicase II 8 kDa subunit, CTC box-binding factor 85 kDa subunit, DNA repa... | |||
TMPH-02203 | THRA Protein, Human, Recombinant (His) | Human | E. coli |
Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.; Does not bind thyroid hormone and functions as a... | |||
TMPY-03502 | PAX8 Protein, Human, Recombinant (His) | Human | E. coli |
PAX8 gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. PAX8 i... | |||
TMPH-02685 | GPHB5 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Functions as a heterodimeric glycoprotein hormone with GPHA2 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production. Plays a central role in controlling thyroid ce... | |||
TMPH-02242 | Transthyretin Protein, Human, Recombinant (hFc & Myc) | Human | HEK293 Cells |
Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. | |||
TMPH-03262 | Cathepsin K Protein, Rat, Recombinant (His) | Rat | E. coli |
Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in... | |||
TMPH-02684 | GPHB5 Protein, Mouse, Recombinant (His) | Mouse | P. pastoris (Yeast) |
Functions as a heterodimeric glycoprotein hormone with GPHA2 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production. Plays a central role in controlling thyroid ce... | |||
TMPH-02565 | Cathepsin K Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Thiol protease involved in osteoclastic bone resorption. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thy... | |||
TMPH-02204 | THRB Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine. | |||
TMPH-02947 | Transthyretin Protein, Mouse, Recombinant | Mouse | E. coli |
Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. Transthyretin Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13.... | |||
TMPH-02120 | SLC5A5 Protein, Human, Recombinant (His) | Human | E. coli |
Mediates iodide uptake in the thyroid gland. SLC5A5 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 17.4 kDa and the accession number is Q92... | |||
TMPH-03385 | Thyroglobulin Protein, Rat, Recombinant (His & SUMO) | Rat | E. coli |
Acts as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). The synthesis of T3 and T4 involves iodination of selected tyrosine residues of TG/thyroglobulin followed by ... | |||
TMPH-03387 | TSHB Protein, Rat, Recombinant (His & Myc) | Rat | P. pastoris (Yeast) |
Indispensable for the control of thyroid structure and metabolism. TSHB Protein, Rat, Recombinant (His & Myc) is expressed in yeast with N-6xHis and C-Myc tag. The predicted molecular weight is 16.4 kDa and the accession... | |||
TMPY-01584 | PR-Set7 Protein, Human, Recombinant | Human | E. coli |
KMT5A (known as PR-Set7/9, SETD8 and SET8), a member of the SET domain containing methyltransferase family specifically targeting H4K20 for methylation, has been implicated in multiple biological processes. Inhibition of... | |||
TMPH-01061 | Cathepsin K Protein, Human, Recombinant (His) | Human | E. coli |
Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in... | |||
TMPH-02946 | Transthyretin Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. Transthyretin Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. Th... | |||
TMPH-03386 | TSHB Protein, Rat, Recombinant (E. coli, His & Myc) | Rat | E. coli |
Indispensable for the control of thyroid structure and metabolism. TSHB Protein, Rat, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight... | |||
TMPJ-01319 | TINAGL1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
TINAGL1 is a secreted protein and contains one SMB (somatomedin-B) domain. TINAGL1 is expressed in aorta, lymph nodes, heart, bone marrow, placenta, lung, kidney, skeletal muscle, pancreas, thyroid, adrenal gland and so ... | |||
TMPY-00483 | Parvalbumin/PVALB Protein, Human, Recombinant (His) | Human | E. coli |
Parvalbumins (PVALBs) are particularly abundant in the fast-contracting muscles and correlate positively with muscle relaxation speed in amphibians and fishes. The loss of PVALB plays a role in the pathogenesis of thyroi... | |||
TMPH-01059 | Cathepsin B Protein, Human, Recombinant (GST) | Human | E. coli |
Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Cleaves matrix extracellular phosphoglycoprotein MEPE. Involved in the solubilization of cross-linked TG/thyroglobuli... | |||
TMPH-01251 | DUSP26 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis... | |||
TMPY-01617 | SULT1B1 Protein, Human, Recombinant (His) | Human | E. coli |
Sulfotransferase family cytosolic 1B member 1, also known as Sulfotransferase 1B1, Sulfotransferase 1B2, Thyroid hormone sulfotransferase, SULT1B1 and ST1B2, is a cytoplasm protein that belongs to the sulfotransferase 1 ... | |||
TMPH-03377 | SULT1B1 Protein, Rat, Recombinant (His & Myc & SUMO) | Rat | E. coli |
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of dopamine, small phenols such as 1-naphthol and p-nitrophenol and thyroid hormones, including ... | |||
TMPJ-00656 | SULT1C2 Protein, Human, Recombinant (His) | Human | E. coli |
Sulfotransferase 1C2 (SULT1C2) is a cytosolic enzyme member of the Sulfotransferase 1 family. Human SULT1C2 is primarily expressed in the adult stomach, kidney and thyroid gland, and in the fetal kidney and liver. SULT1C... | |||
TMPJ-00793 | TPM3 Protein, Human, Recombinant | Human | E. coli |
Tropomyosin Alpha-3 Chain (TPM3) is a member of the Tropomyosin family. TPM3 exists as a heterodimer consisting of an alpha and a beta chain. TPM3 plays a central role in association with the Troponin complex and in the ... | |||
TMPJ-00705 | BCAS2 Protein, Human, Recombinant (His, T7) | Human | E. coli |
Breast Carcinoma-Amplified Sequence 2 (BCAS2) is a member of the SPF27 family. BCAS2 is a nuclear protein and widely expressed in many rtissues. BCAS2 is identified as being overexpressed in various breast cancer cell li... | |||
TMPJ-01260 | WBP2 Protein, Human, Recombinant (His) | Human | E. coli |
WW Domain-Binding Protein 2 (WBP2) is a ubiquitous protein that contains one GRAM domain. The WW domain is composed of 38 to 40 semi-conserved AA shared by proteins of diverse functions including structural, regulatory, ... | |||
TMPJ-00701 | Carbonic Anhydrase 11 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Carbonic Anhydrase-Related Protein 11 (CA11) is a secreted protein member of the α-carbonic anhydrase family. Carbonic Anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of ... | |||
TMPY-04445 | PDK4 Protein, Mouse, Recombinant (His & GST) | Mouse | Baculovirus Insect Cells |
Pyruvate dehydrogenase kinase 4 (PDK4) is a mitochondrial protein that regulates the TCA cycle.PDK4, a vital mitochondrial protein, controls the switch between glycolysis and oxidative phosphorylation based upon nutrient... | |||
TMPY-03613 | COMMD8 Protein, Human, Recombinant (His) | Human | E. coli |
COMMD8 is a member of the COMMD family. Members of this family are a group of evolutionary conserved proteins that share a common COMM domain at the extreme C-terminus, which provides an interface for protein-protein int... | |||
TMPY-03811 | KCT2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
C5orf15 (Chromosome 5 Open Reading Frame 15, also known as KCT2) is a Protein Coding gene. KCT2 gene maps to human chromosome 5q31.1 and is conserved in human, chimpanzee, cow, rat, and chicken. KCT2 is a 265 amino acid ... | |||
TMPJ-00456 | APRIL/TNFSF13 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Tumor necrosis factor ligand superfamily member 13 belongs to the tumor necrosis factor family. It is also known as APRIL, TALL2, TRDL1, and CD256. It is synthesized as a 32 kDa proprotein which is cleaved by furin in th... | |||
TMPY-02394 | IMPA1 Protein, Human, Recombinant (His) | Human | E. coli |
IMPA1 (Inositol Monophosphatase 1) is a Protein Coding gene. This gene encodes an enzyme that dephosphorylates Myo-inositol monophosphate to generate free Myo-inositol, a precursor of phosphatidylinositol, and is, theref... | |||
TMPJ-01320 | BSSP-4 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Brain-Specific Serine Protease 4 (BSSP-4) is a serine protease that preferentially cleaves the synthetic substrate H-D-Leu-Thr-Arg-pNA compared to tosyl-Gly-Pro-Arg-pNA. BSSP-4 is expressed abundantly in the epithelial c... | |||
TMPY-01451 | MESDC2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
MESD (Mesoderm Development LRP Chaperone) is a Protein Coding gene. LDLR chaperone MESD, also known as Mesoderm development protein, Mesoderm development candidate 2, Renal carcinoma antigen NY-REN-61, and MESDC2, is a m... | |||
TMPY-03857 | MMGT1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
MMGT1 (Membrane Magnesium Transporter 1, also known as EMC5 and TMEM32) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. The encoded protein belongs to the membrane magnesium transport... | |||
TMPY-03615 | CSEN Protein, Human, Recombinant (His) | Human | E. coli |
KCNIP3 (Potassium Voltage-Gated Channel Interacting Protein 3, also known as CSEN) is a Protein Coding gene. CSEN is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to th... | |||
TMPJ-01283 | UGRP1 Protein, Human, Recombinant | Human | E. coli |
Uteroglobin-Related Protein 1 (UGRP1) belongs to the secretoglobin family which has been suggested to play a role in lung inflammation and allergic diseases. UGRP1 is a 17 kDa secreted homodimeric protein that shows amin... | |||
TMPH-02221 | TRIM24 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Transcriptional coactivator that interacts with numerous nuclear receptors and coactivators and modulates the transcription of target genes. Interacts with chromatin depending on histone H3 modifications, having the high... | |||
TMPY-03616 | NAPG Protein, Human, Recombinant (His) | Human | E. coli |
NAPG (NSF Attachment Protein Gamma, also known as gamma SNAP) is a Protein Coding gene. This gene encodes soluble NSF attachment protein gamma. The encoded protein mediates platelet exocytosis and controls the membrane f... | |||
TMPY-02883 | C1D Protein, Human, Recombinant (GST) | Human | E. coli |
C1D nuclear receptor corepressor belongs to the C1D family. It is a DNA binding and apoptosis-inducing protein.C1D nuclear receptor corepressorinteracts with TSNAX and DNA-PKcs. It acts as a corepressor for the thyroid h... | |||
TMPY-03280 | RAMP3 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
RAMP3 belongs to the RAMP family. Members of this family are single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs have a wide biological distribution; high concent... | |||
TMPY-04930 | Notch 2 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
NOTCH2 (Notch Receptor 2) is a Protein Coding gene. This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics and play a role in a variety of dev... | |||
TMPY-02979 | HMGN3 Protein, Human, Recombinant (His) | Human | E. coli |
HMGN3 belongs to the HMGN family and is expressed in the kidney, lung, pancreas, testis, skeletal muscle, heart, thyroid gland, pituitary gland, prostate, and uterus. Members of the HMGN family bind to nucleosomes withou... | |||
TMPY-01551 | Serpin B8 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus Insect Cells |
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesi... | |||
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カタログ番号 | 製品名 | ||
---|---|---|---|
L1510 | Nuclear Receptor Compound Library | 531 compounds | |
A unique collection of 531 nuclear receptor signaling targeted compounds for high throughput and high content screening; | |||
L2400 | Endocrinology-Hormone Compound Library | 784 compounds | |
A unique collection of 784 compounds targeting endocrine system for high throughput screening (HTS) and high content screening (HCS) for new drugs; |