Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ABC99 is a selective irreversible inhibitor of the wnt-deacylating enzyme. ABC99 inhibited NOTUM (IC50: 13 nM). It also showed excellent selectivity across the serine hydrolase family.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
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1 mg | 在庫あり | ¥ 40,500 | |||
5 mg | 在庫あり | ¥ 85,500 | |||
10 mg | 在庫あり | ¥ 128,000 | |||
25 mg | 在庫あり | ¥ 206,000 | |||
50 mg | 在庫あり | ¥ 280,000 | |||
100 mg | 在庫あり | ¥ 379,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 86,000 |
説明 | ABC99 is a selective irreversible inhibitor of the wnt-deacylating enzyme. ABC99 inhibited NOTUM (IC50: 13 nM). It also showed excellent selectivity across the serine hydrolase family. |
In vitro | ABC99 (0.1~10 μΜ; 2 hours; SW620 cells) inhibits NOTUM in a concentration-dependent manner and preserves Wnt-3A activity in the presence of NOTUM in a concentration-dependent manner[1]. |
別名 | ABC 99, ABC-99 |
分子量 | 456.88 |
分子式 | C22H21ClN4O5 |
CAS No. | 2331255-53-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 20 mg/mL (43.8 mM), Sonication and heating to 80℃ are recommended.
You can also refer to dose conversion for different animals. 詳細
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ABC99 2331255-53-7 Cytoskeletal Signaling Stem Cells Wnt/beta-catenin ABC 99 ABC-99 Inhibitor inhibitor inhibit