Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AMG 579 is an efficacious and selective inhibitor of PDE10A (IC50 = 0.1 nM).
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 11,000 | |||
2 mg | 在庫あり | ¥ 16,000 | |||
5 mg | 在庫あり | ¥ 26,000 | |||
10 mg | 在庫あり | ¥ 41,000 | |||
25 mg | 在庫あり | ¥ 72,000 | |||
50 mg | 在庫あり | ¥ 100,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 29,000 |
説明 | AMG 579 is an efficacious and selective inhibitor of PDE10A (IC50 = 0.1 nM). |
ターゲット&IC50 | PDE10A:0.1 nM |
In vivo | AMG 579 statistically reduces PCP-induced behavior in rats within 2 hours. In the PCP-LMA model, the minimum effective dose of AMG 579 was 0.3 mg/kg. AMG 579 has an excellent oral bioavailability of 72% in dogs[1]. |
別名 | AMG-579 |
分子量 | 441.48 |
分子式 | C25H23N5O3 |
CAS No. | 1227067-61-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 37.8 mg/mL (85.6 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
AMG 579 1227067-61-9 Metabolism PDE AMG-579 AMG579 Inhibitor inhibitor inhibit