Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AMG-458 is a potent c-Met inhibitor with Ki of 1.2 nM, ~350-fold selectivity for c-Met than VEGFR2 in cells.
説明 | AMG-458 is a potent c-Met inhibitor with Ki of 1.2 nM, ~350-fold selectivity for c-Met than VEGFR2 in cells. |
ターゲット&IC50 | c-Met (human):1.2 nM(Ki) |
別名 | AMG 458 |
分子量 | 539.58 |
分子式 | C30H29N5O5 |
CAS No. | 913376-83-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 21 mg/mL (38.91 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
AMG-458 913376-83-7 Tyrosine Kinase/Adaptors c-Met/HGFR AMG458 inhibit Inhibitor AMG 458 inhibitor