Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AZ13705339 is an effective inhibitor of PAK1 with an IC50 of 0.33 nM and a Kd of 0.28 nM. AZ13705339 binds PAK2 with a Kd of 0.32 nM. AZ13705339 can be used in studies about cancers.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
2 mg | 在庫あり | ¥ 9,000 | |||
5 mg | 在庫あり | ¥ 15,000 | |||
10 mg | 在庫あり | ¥ 22,500 | |||
25 mg | 在庫あり | ¥ 51,000 | |||
50 mg | 在庫あり | ¥ 81,500 | |||
100 mg | 在庫あり | ¥ 131,500 |
説明 | AZ13705339 is an effective inhibitor of PAK1 with an IC50 of 0.33 nM and a Kd of 0.28 nM. AZ13705339 binds PAK2 with a Kd of 0.32 nM. AZ13705339 can be used in studies about cancers. |
In vitro | AZ13705339 (300 nM) prevents Siglec-8 binding-induced eosinophil death[2]. In Namalwa cells, AZ13705339 (1 μM) inhibits αIgM-controlled but not PMA-induced adhesion[3]. |
In vivo | In rats, AZ13705339 (100 mg/kg, p.o.) exhibits moderate clearance and Cmax of 7.7 μM[1]. |
別名 | AZ-13705339, AZ 13705339 |
分子量 | 629.75 |
分子式 | C33H36FN7O3S |
CAS No. | 2016806-57-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 225 mg/mL (357.3 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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AZ13705339 2016806-57-6 Cytoskeletal Signaling PAK AZ-13705339 AZ 13705339 Inhibitor inhibitor inhibit