Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AZ1495 is an oral active inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4), with IC50 values of 5 nM and 23 nM for IRAK4 and IRAK1, respectively. Which Shows activity in treatment of mutant MYD88L265P diffuse large B-cell lymphoma (DLBCL).
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 34,000 | |||
5 mg | 在庫あり | ¥ 64,000 | |||
10 mg | 在庫あり | ¥ 104,500 | |||
25 mg | 在庫あり | ¥ 148,500 | |||
50 mg | 在庫あり | ¥ 209,500 | |||
100 mg | 在庫あり | ¥ 319,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 72,000 |
説明 | AZ1495 is an oral active inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4), with IC50 values of 5 nM and 23 nM for IRAK4 and IRAK1, respectively. Which Shows activity in treatment of mutant MYD88L265P diffuse large B-cell lymphoma (DLBCL). |
ターゲット&IC50 | CLK1:50 nM, CLK2:5 nM, IRAK4:5 nM, CLK4:8 nM, Haspin:4 nM, IRAK1:23 nM |
分子量 | 385.5 |
分子式 | C21H31N5O2 |
CAS No. | 2196204-23-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mg/mL (25.94 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
AZ1495 2196204-23-4 Cell Cycle/Checkpoint Immunology/Inflammation NF-Κb IRAK Haspin Kinase CDK Interleukin-1 receptor associated kinase interleukin-1 receptor associated kinase 4 (IRAK4) inhibit AZ 1495 cancer IL-1R associated kinase weak base diffuse large B-cell lymphoma (DLBCL) Inhibitor interleukin-1 receptor associated kinase 1 (IRAK1) AZ-1495 inhibitor