Powder: -20°C for 3 years | In solvent: -80°C for 1 year
1. Acetylcorynoline (O-Acetylcorynoline) has antifungal、anti-inflammatory activity. 2. Acetylcorynoline may be one of the potent immunosuppressive agents through the blockage of dendritic cells maturation and function. 3. Acetylcorynoline is potential as a possible antiparkinsonian drug. (1) Significantly decreases dopaminergic neuron degeneration induced by 6-hydroxydopamine in BZ555 strain; (2) Prevents α-synuclein aggregation; (3) Restores food-sensing behavior, and dopamine levels; (4) Prolongs life-span in 6-hydroxydopamine-treated N2 strain. 4. Acetylcorynoline may exert its effects by decreasing egl-1 expression to suppress apoptosis pathways and by increasing rpn5 expression to enhance the activity of proteasomes.
説明 | 1. Acetylcorynoline (O-Acetylcorynoline) has antifungal、anti-inflammatory activity. 2. Acetylcorynoline may be one of the potent immunosuppressive agents through the blockage of dendritic cells maturation and function. 3. Acetylcorynoline is potential as a possible antiparkinsonian drug. (1) Significantly decreases dopaminergic neuron degeneration induced by 6-hydroxydopamine in BZ555 strain; (2) Prevents α-synuclein aggregation; (3) Restores food-sensing behavior, and dopamine levels; (4) Prolongs life-span in 6-hydroxydopamine-treated N2 strain. 4. Acetylcorynoline may exert its effects by decreasing egl-1 expression to suppress apoptosis pathways and by increasing rpn5 expression to enhance the activity of proteasomes. |
植物由来 |
別名 | (+)-Corynoline Acetate, O-Acetylcorynoline |
分子量 | 409.43 |
分子式 | C23H23NO6 |
CAS No. | 18797-80-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 4.1 mg/mL (10 mM)
You can also refer to dose conversion for different animals. 詳細
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Acetylcorynoline 18797-80-3 Microbiology/Virology Antifungal (+)-Corynoline Acetate O-Acetylcorynoline inhibit Corynoline Acetate Inhibitor inhibitor