Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Amifampridine (3,4-Diaminopyridine) is predominantly in the treatment of a number of rare muscle diseases. Amifampridine works by blocking potassium channel efflux in nerve terminals so that action potential duration is increased. Ca2+ channels can then be open for a longer time and allow greater acetylcholine release to stimulate muscle at the end plate.
説明 | Amifampridine (3,4-Diaminopyridine) is predominantly in the treatment of a number of rare muscle diseases. Amifampridine works by blocking potassium channel efflux in nerve terminals so that action potential duration is increased. Ca2+ channels can then be open for a longer time and allow greater acetylcholine release to stimulate muscle at the end plate. |
別名 | 3,4-Pyridinediamine, Pyridine-3,4-Diamine, 3,4-Diaminopyridine |
分子量 | 109.13 |
分子式 | C5H7N3 |
CAS No. | 54-96-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 24 mg/mL
DMSO: 60 mg/mL (549.8 mM)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Amifampridine 54-96-6 Others LEMS Oral Potassium Channel KcsA 3,4-Pyridinediamine voltage-gated potassium myasthenic syndrome inhibit Pyridine-3,4-Diamine Inhibitor neurological disease 3,4-Diaminopyridine neuromuscular junction inhibitor