keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Anabasine ((S)-Anabasine) is an alkaloid extracted from tobacco. Anabasine is a full agonist of nicotinic acetylcholine receptors (nAChRs) with insecticidal activity. Anabasine depolarizes TE671 cells endogenously expressing human myotypic nAChRs.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
25 mg | 在庫あり | ¥ 9,000 | |||
50 mg | 在庫あり | お問い合わせ | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 7,000 |
説明 | Anabasine ((S)-Anabasine) is an alkaloid extracted from tobacco. Anabasine is a full agonist of nicotinic acetylcholine receptors (nAChRs) with insecticidal activity. Anabasine depolarizes TE671 cells endogenously expressing human myotypic nAChRs. |
In vivo | Anabasine significantly reverses the impairment at doses of 0.2 mg/kg (p<0.05) and 2 mg/kg (p<0.025). When administered alone, Anabasine does not have any significant effects on response latency. Interestingly, the 0.06 mg/kg Anabasine dose exacerbates the dizocilpine-induced impairment, showing a significant increase in non-response trials (p<0.05) compared with dizocilpine alone. It's important to note that none of the Anabasine doses affect choice accuracy on their own[2]. |
植物由来 |
別名 | (S)-Anabasine, (-)-Anabasine |
分子量 | 162.23 |
分子式 | C10H14N2 |
CAS No. | 494-52-0 |
keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (308.20 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Anabasine 494-52-0 Neuroscience AChR (S)-Anabasine (-)-Anabasine Inhibitor inhibitor inhibit