Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BF738735 is a selective inhibitor of phosphatidylinositol 4-kinase III beta (PI4KIIIβ, IC50 = 5.7 nM) showing higher activity over α(IC50 = 1.7 μM). BF738735 exhibits a broad spectrum of antiviral activity.
パッケージサイズ | 在庫状況 | 単価(税別) | |
---|---|---|---|
1 mg | 在庫あり | ¥ 9,500 | |
2 mg | 在庫あり | ¥ 13,000 | |
5 mg | 在庫あり | ¥ 20,500 | |
10 mg | 在庫あり | ¥ 35,500 | |
25 mg | 在庫あり | ¥ 78,000 | |
50 mg | 約6-8 週間 | お問い合わせ | |
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 22,500 |
ターゲット&IC50 | PI4KIIIα:1.7 μM, PI4KIIIβ:5.7 nM |
In vivo | BF738735 demonstrates favorable tolerability in test subjects, achieving effective plasma concentrations of the antiviral. Notably, a complete inhibition of the target activity is achieved at a dosage of 25 mg/kg, while a partial inhibition is observed with a 5 mg/kg dose[2]. |
分子量 | 426.46 |
分子式 | C21H19FN4O3S |
CAS No. | 1436383-95-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 125 mg/mL (293.11 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
BF738735 1436383-95-7 Immunology/Inflammation PI3K/Akt/mTOR signaling Antiviral PI4K Phosphatidylinositol 4 kinases Inhibitor PI4 kinases BF-738735 inhibit Reverse Transcriptase BF 738735 inhibitor