Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BML-284 (Wnt agonist 1) is a potent, selective and , cell-permeable Wnt signaling activator.
説明 | BML-284 (Wnt agonist 1) is a potent, selective and , cell-permeable Wnt signaling activator. |
ターゲット&IC50 | TCF-dependent transcriptional activity:700 nM (EC50) |
In vitro | Wnt agonist 1 does not inhibit the activity of GSK-3β, and may be a useful tool in the study of physiological processes that involve the Wnt pathway. [1] |
In vivo | In a Xenopus model, Wnt agonist 1 (10 μM) mimics the effects of Wnt at the whole-organism level, and affects Xenopus embryonic head specification. [1] |
別名 | Wnt agonist 1 |
分子量 | 350.37 |
分子式 | C19H18N4O3 |
CAS No. | 853220-52-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: < 1 mg/mL (insoluble or slightly soluble)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 77 mg/mL (199.05 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
BML-284 853220-52-7 Cytoskeletal Signaling Stem Cells Wnt/beta-catenin N-cadherin E-cadherin BML284 malformed phenotype Wnt inhibit AGS BML 284 Wnt agonist 1 TCF Inhibitor cardiac defect MNK45 inhibitor