Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BZAD01 is a selective NMDA NR1A/2B receptor antagonist.
説明 | BZAD01 is a selective NMDA NR1A/2B receptor antagonist. |
In vivo | Parkinsonism was induced by microinjection of the toxin, 6-hydroxydopamine (6-OHDA) into the medial forebrain bundle (MFB) of 40 Sprague-Dawley rats. Parkinsonism and the efficacy of drugs were assessed using a battery of behavioural tests including balance beam, apomorphine-induced rotation, body axis bias or "curling", head position bias and disengage sensorimotor latency test. The main effects were that BZAD01 co-administration prevented chronic levodopa-induced potentiation of apomorphine rotation. However levodopa-treated rats were slower than either controls or BZAD-01-treated rats in the locomotor test[2]. |
別名 | BZAD-01, BZAD 01 |
分子量 | 362.27 |
分子式 | C16H12F6N2O |
CAS No. | 305339-41-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/ml (151.82 mM)
You can also refer to dose conversion for different animals. 詳細
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BZAD01 305339-41-7 Neuroscience NMDAR Inhibitor NR2B NMDA BZAD-01 iGluR Ionotropic glutamate receptors BZAD 01 inhibit inhibitor