Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Bis-T-23 is a promoter of actin-dependent dynamin oligomerization, an HIV-I integrase inhibitor, and a Telstar derivative. Bis-T-23 promotes actin-dependent dynamin oligomerization. Bis-T-23 can be used in studies of HIV and chronic kidney disease (CKD).
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 80,500 |
5 mg | 在庫あり | ¥ 190,000 |
10 mg | 在庫あり | ¥ 259,500 |
25 mg | 在庫あり | ¥ 365,000 |
50 mg | 在庫あり | ¥ 454,500 |
100 mg | 在庫あり | ¥ 574,000 |
500 mg | 在庫あり | ¥ 1,124,500 |
説明 | Bis-T-23 is a promoter of actin-dependent dynamin oligomerization, an HIV-I integrase inhibitor, and a Telstar derivative. Bis-T-23 promotes actin-dependent dynamin oligomerization. Bis-T-23 can be used in studies of HIV and chronic kidney disease (CKD). |
In vitro |
Bis-T-23 (AG1717) (0.18 μM) inhibits HIV-1 integrase.[5] AG1717 (2 μM) inhibits the binding of integrase to substrate DNA.[5] |
In vivo |
Bis-T-23 (1 ng) targets actin-dependent kinesin oligomerization in podocytes to promote normal GFB function.[6] Bis-T-23 (i.p. ; 20, 40 mg/kg) improves proteinuria by altering actin kinetics.[6] Bis-T-23 (i.p. ; 20, 40 mg/kg) ameliorates or prevents proteinuria and reduces thylakoid matrix expansion in various genetic and chronic glomerular disease models in rodents.[6] |
別名 | Bis T-23, Bis-T 23, AG1717 |
分子量 | 480.43 |
分子式 | C23H20N4O8 |
CAS No. | 171674-76-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: Insoluble
DMSO: 12.01 mg/ml (25 mM)
You can also refer to dose conversion for different animals. 詳細
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Bis-T-23 171674-76-3 Microbiology/Virology Proteases/Proteasome HIV Protease Bis T-23 AG-1717 Bis-T 23 AG 1717 AG1717 Inhibitor inhibitor inhibit