Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Flavopiridol (Alvocidib) (Alvocidib) competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM. It is 7.5-fold more selective for CDK1, 2, 4, 6 versus CDK7. Flavopiridol is initially found to inhibit EGFR and PKA. Phase 1/2.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
5 mg | 在庫あり | ¥ 18,000 | |||
10 mg | 在庫あり | ¥ 24,000 | |||
25 mg | 在庫あり | ¥ 57,000 | |||
50 mg | 在庫あり | ¥ 91,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 21,500 |
説明 | Flavopiridol (Alvocidib) (Alvocidib) competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM. It is 7.5-fold more selective for CDK1, 2, 4, 6 versus CDK7. Flavopiridol is initially found to inhibit EGFR and PKA. Phase 1/2. |
ターゲット&IC50 | CDK1:40 nM, CDK4:40 nM, CDK2:40 nM, CDK6:40 nM |
別名 | L868275, Alvocidib, NSC 649890 HCl, HMR-1275 |
分子量 | 401.84 |
分子式 | C21H20ClNO5 |
CAS No. | 146426-40-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 12 mg/mL (29.9 mM)
Ethanol: 8 mg/mL (19.9 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Flavopiridol 146426-40-6 Apoptosis Autophagy Cell Cycle/Checkpoint Microbiology/Virology Proteases/Proteasome CDK HIV Protease L868275 HMR 1275 inhibit L86-8275 L-868275 L 868275 Alvocidib Cyclin dependent kinase Inhibitor NSC 649890 HCl Human immunodeficiency virus HIV HMR1275 HMR-1275 inhibitor