Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CCTA-1523 is an efflux function of ABCG2 inhibitor. CCTA-1523 selectively reverses ABCG2-mediated MDR in cancer cells.
説明 | CCTA-1523 is an efflux function of ABCG2 inhibitor. CCTA-1523 selectively reverses ABCG2-mediated MDR in cancer cells. |
In vitro | CCTA-1523 (5μM) sensitized the ABCG2 overexpressing cancer cells and ABCG2 transfected cells to the substrate chemotherapeutic drugs[1]. |
In vivo | Co-administration of CCTA-1523 restored the in vivo antitumor activity of doxorubicin in ABCG2 overexpressing tumor xenografts[1]. |
分子量 | 340.2 |
分子式 | C16H15Cl2NO3 |
CAS No. | 1616271-41-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (146.97 mM)
You can also refer to dose conversion for different animals. 詳細
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CCTA-1523 1616271-41-0 Membrane transporter/Ion channel Others ABC CCTA 1523 CCTA1523 Inhibitor inhibitor inhibit