Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CID 5951923 is an inhibitor of KLF5 transcription factor with an IC50 of 603 nM.
説明 | CID 5951923 is an inhibitor of KLF5 transcription factor with an IC50 of 603 nM. |
ターゲット&IC50 | KLF5:603 nM (IC50) |
In vitro | CID 5951923 (10 μM) inhibits the proliferation of cancer cell lines mainly in highly expressing KLF5 cells. CID 5951923 (0.001, 0.01, 0.1, 1, 10, 100 μM) inhibits proliferation of DLD-1 cells in a dose-dependent manner. CID 5951923 (10 μM) significantly decreases endogenous KLF5 levels in the DLD-1 cells, downregulates EGR1, and increases phosphorylation levels of pEGFFpY1068[1]. |
分子量 | 382.39 |
分子式 | C16H18N2O7S |
CAS No. | 749872-43-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 3.82 mg/mL (10 mM)
You can also refer to dose conversion for different animals. 詳細
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CID 5951923 749872-43-3 Cell Cycle/Checkpoint DNA Damage/DNA Repair DNA/RNA Synthesis Krüppel-like factor CID5951923 KLF5 inhibit cancer factor KLF CID-5951923 transcription Inhibitor Krüppel-like inhibitor