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Search Results for " transcription "

ターゲット

IL Receptor

354

阻害剤

天然化合物

703

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T12218	NFAT Transcription Factor Regulator-1		IL Receptor
	NFAT Transcription Factor Regulator-1 is an synthesis inhibitor of IL-2 (IC50 of 182 nM).		IL Receptor
TP2291	Signal transducer and activator of transcription 6 fragment		Others
	The signal transducer and activator of transcription 6 fragments is a peptide with the sequence H2N-Ser-Tyr-Trp-Ser-Asp-Arg-Leu-Ile-Ile-OH, MW= 1152.3.		Others
T8890	653-47 hydrochloride		Epigenetic Reader Domain
	653-47 hydrochloride is a potentiator, significantly potentiates the cAMP-response element binding protein (CREB) inhibitory activity of 666-15. It is also a very weak CREB inhibitor with IC50 of 26.3 μM.		Epigenetic Reader Domain
T40661	ML-60218		DNA/RNA Synthesis
	ML-60218 is an inhibitor of broad-spectrum RNA pol III with IC50s of 32 and 27 μM for Saccharomyces cerevisiae and human. ML-60218 disrupts already assembled viroplasms and hampers the formation of new viroplasms.		DNA/RNA Synthesis
T22062	CCG-100602		Rho , Ras
	CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells (IC50 :9.8 μM).		Rho , Ras
T14495	Baloxavir	Baloxavir acid,S-033447	Influenza Virus
	Baloxavir (S-033447) is a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit.		Influenza Virus
T22667	CID 5951923		DNA/RNA Synthesis
	CID 5951923 is an inhibitor of KLF5 transcription factor with an IC50 of 603 nM.		DNA/RNA Synthesis
T1767	BMH-21	BMH21	DNA/RNA Synthesis
	BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.		DNA/RNA Synthesis
T27029	Cjoc42	cjoc 42,cjoc-42
	Cjoc42 is an inhibitor of gankyrin, an ankyrin-repeat oncoprotein whose overexpression has been implicated in the development of many cancer types. cjoc42 prevents the decrease in p53 protein levels normally associated w...
T21767	MS37452		Others , Histone Methyltransferase
	MS37452 is a competitive inhibitor of CBX7 chromodomain binding to H3K27me3 (Ki = 43 µM).		Others , Histone Methyltransferase
T4356	POL1-IN-1	Compound 3A	DNA/RNA Synthesis
	POL1-IN-1 (Compound 3A) can effectively inhibit the transcription of RNA polymerase I in the A375 malignant melanoma cell line but has no effect on polymerase II.		DNA/RNA Synthesis
T22461	YKL-5-124		CDK
	YKL-5-124, a potent, selective and covalent CDK7 inhibitor with an IC50 of 9.7 nM, 1300 nM and 3020 nM for CDK7/Mat1/CycH, CDK2 and CDK9 respectively, displays biochemical and cellular selectivity for CDK7 over CDK12/13...		CDK
T23820	BRD32048	BRD-32048,BRD 32048	DNA/RNA Synthesis
	BRD32048 is the ETV1 transcription factor oncoprotein inhibitor.		DNA/RNA Synthesis
T13166	TK216		Others , DNA/RNA Synthesis
	TK216 is a potent inhibitor of E26 transformation-specific (ETS) with anticancer activity.		Others , DNA/RNA Synthesis
T12006	Metarrestin	ML246	DNA/RNA Synthesis
	Metarrestin (ML246) is a first-in-class perinucleolar compartment inhibitor with a favorable PK profile, which effectively suppresses metastasis. Metarrestin disrupts the nucleolar structure and inhibits RNA polymerase (...		DNA/RNA Synthesis
T10760	Ceramides Mixture		Telomerase
	Ceramides Mixture, an endogenous ceramide, consists of hydroxy and non-hydroxy fatty acid-containing ceramides. It is involved in the regulation of cell cycle arrest, growth inhibition, and modulation of telomerase activ...		Telomerase
T21807	INCA-6	Triptycene-1,4-quinone	Others
	INCA-6 (Triptycene-1,4-quinone) is a cell-permeable NFAT inhibitor. INCA-6 inhibits of CN-NFAT signaling by targeting of NFAT(P) substrate to the calcineurin (CN) phosphatase site.		Others
T8972	FIT-039		Others , DNA/RNA Synthesis , CDK , HSV
	FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin T1). FIT-039 inhibits replication of HSV-1 (IC50 of 0.69 μM), HSV-2, human adenovirus, and human CMV. FIT-039 is a pr...		Others , DNA/RNA Synthesis , CDK , HSV
T7887	8-Hydroxyquinoline hemisulfate	Oxyquinoline sulfate	Others , Antibacterial , Antibiotic
	8-Hydroxyquinoline hemisulfate (Oxyquinoline sulfate) is an antiseptic with mild fungistatic, bacteriostatic, anthelmintic, and amebicidal action		Others , Antibacterial , Antibiotic
T7764	CCG-222740		ROCK , Rho , Ras
	CCG-222740 is an inhibitor of Rho/MRTF pathway		ROCK , Rho , Ras
T20759	XRP44X	XRP-44-X,XRP 44X,XRP-44X,XRP 44 X	Ras
	XRP44X (XRP 44X) is a potent inhibitor of Ras-Net (Elk-3) pathway.		Ras
T5045	GSK4112	1,1-Dimethylethyl-N-[(4-chlorophenyl)methyl]-N-[(5-nitro-2-thienyl)methyl])glycinate,SR6452	Autophagy
	GSK4112 (SR6452) is a Rev-erbα agonist with EC50 of 0.4 μM, also is a small molecule chemical probe for the cell biology of the nuclear heme receptor Rev-erbα.		Autophagy
T7700	Lersivirine	Lersivirine(UK 453061),UK-453061	HIV Protease , Reverse Transcriptase
	Lersivirine (UK-453061)(UK 453061) is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) under development for HIV infection therapy.		HIV Protease , Reverse Transcriptase
T8841	IMT1	Propanamide, N,N-dimethyl-2-[[4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-,LDC195943(IMT1)	Others , DNA/RNA Synthesis , Mitochondrial Metabolism
	IMT1 (Propanamide, N,N-dimethyl-2-[[4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-) has anticancer activity.		Others , DNA/RNA Synthesis , Mitochondrial Metabolism
T40459	Transcriptional Intermediary Factor 2 (TIF2) (740-753)	Transcriptional Intermediary Factor 2 (TIF2) (740-753)
	Transcriptional Intermediary Factor 2 (TIF2) (740-753) is a 14-amino acid peptide that serves as a coactivator of TIF-2 protein. It specifically covers residues 740-753 of the TIF-2 protein.
T2100	CX-5461		DNA/RNA Synthesis
	CX-5461, a selective inhibitor of rRNA synthesis, suppresses Pol I-driven transcription of rRNA.		DNA/RNA Synthesis
T11131	DW14800		Histone Methyltransferase
	DW14800 is an inhibitor of PRMT5 (IC50 = 17 nM), enhances the transcription of HNF4α, and reduces the level of H4R3me2s.		Histone Methyltransferase
T4302	ICRT3		Apoptosis , Wnt/beta-catenin
	iCRT3 is a Wnt and β-catenin-responsive transcription inhibitor.		Apoptosis , Wnt/beta-catenin
T60619	CDK9-IN-15		CDK
	CDK9-IN-15 is a potent small molecule CDK9 inhibitor, which can block the phosphorylation of positive transcription elongation factor b (P-TEFb) on the C-terminal region of RNA Poly-II by degradation and inhibition of CD...		CDK
T4234	HJC0152 hydrochloride	HJC0152	Apoptosis , STAT
	HJC0152 hydrochloride (HJC0152) is a signal transducer and activator of transcription 3 (STAT3) inhibitor.		Apoptosis , STAT
T23151	Phortress	NSC 710305	AhR
	Phortress (NSC-710305) is a potent AhR ligand with strong binding affinity, which subsequently triggers the transcription of CYP1A1 and induces antitumor activity.		AhR
T15370	GANT 58	NSC 75503	Hedgehog/Smoothened
	GANT 58 (NSC-75503) is a potent antagonist of Gli. Which inhibits GLI1-induced transcription (IC50: 5 μM).		Hedgehog/Smoothened
T21813	OAC3	4-fluoro-N-(1H-indol-5-yl)benzamide	Others
	OAC3 (4-fluoro-N-(1H-indol-5-yl)benzamide) is an activator of octamer-bound transcription factor 4.		Others
T60051	VPC-18005		Others
	VPC-18005 is a luciferase inhibitor. VPC-18005 inhibits ERG-induced transcription and interacts directly with the ERG-ETS domain thereby disrupting the ERG binding to DNA.		Others
T17142	Toxoflavin	Xanthothricin,PKF-118-310,Toxoflavine	Wnt/beta-catenin , Antibacterial , Antibiotic
	Toxoflavin (Xanthothricin) is an antagonist of transcription factor 4 (TCF4)/β-catenin complex. Toxoflavin also acts as an inhibitor of KDM4A.		Wnt/beta-catenin , Antibacterial , Antibiotic
T2014	CCG-1423	CCG1423	LRRK2 , Rho , Ras
	CCG-1423, a selective RhoA pathway inhibitor, suppresses SRF-mediated transcription.		LRRK2 , Rho , Ras
TP2506	Ser-Asn-Thr-Arg
	Ser-Asn-Thr-Arg is a tetrapeptide compound formed by truncation of a transcription activator-like effector.
T1095	Sparfloxacin	AT-4140,PD 131501,Zagam,CI-978	DNA gyrase , Topoisomerase , Antibacterial , Antibiotic
	Sparfloxacin (CI-978) is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase, thereby inhibiting DNA replication and transcription.		DNA gyrase , Topoisomerase , Antibacterial , Antibiotic
T5416	T-5224		MMP
	T-5224 is a transcription factor c-Fos/AP-1 inhibitor, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcription factors.		MMP
T60160	STX-0119		STAT
	STX-0119 is a selective, orally active STAT3 dimerization inhibitor. STX-0119 inhibits STAT3 transcription with an IC50 of 74 μM.		STAT
T3460	HhAntag		Hedgehog/Smoothened , Smo
	HhAntag is a small molecule inhibitor of GLI1-mediated transcription, an essential down-stream element of the Hedgehog (Hh) pathway with the anti-tumor activity.		Hedgehog/Smoothened , Smo
T6113	ICG-001		Apoptosis , Epigenetic Reader Domain , Wnt/beta-catenin
	ICG-001 antagonizes Wnt/β-catenin/TCF-mediated transcription and specifically binds to element-binding protein (CBP) with IC50 of 3 μM, but is not the related transcriptional coactivator p300.		Apoptosis , Epigenetic Reader Domain , Wnt/beta-catenin
T35544	ML115		STAT
	ML115 is a potent and selective activator of transcription 3 (STAT3), with abn EC50 of 2.0 nM, and is inactive against the related STAT1 and NFκB anti-targets.		STAT
T9632	CDK9-IN-30		HIV Protease
	CDK9-IN-30 is one of the Tat peptide derivatives and inhibits HIV-1 long terminal repeat-activated transcription.		HIV Protease
T14969	CINPA1	CINPA-1,CINPA 1	Others
	CINPA1 (CINPA 1) is a selective inhibitor of constitutive androstane receptor (CAR) with an IC50 of 70 nM for CAR-mediated transcription. CINPA1 can be used in studies about CAR function.		Others
T28578	Ro24-7429	Ro 24-7429,Ro-24-7429,Ro 247429	HIV Protease
	Ro24-7429 is an effective and orally active antagonist of HIV-1 transactivator protein Tat and an inhibitor of a runt-related transcription factor 1. Ro24-7429 has anti-HIV, antifibrotic, and anti-inflammatory effects.		HIV Protease
T60031	NRX-1933
	NRX-1933 is a molecular glue and enhances the interaction between an oncogenic transcription factor, β-Catenin, and its cognate E3 ligase, SCFβ-TrCP.
T2040	OAC1	BAS 00287861	OCT
	OAC1 (BAS 00287861) is a compound activating Octamer-binding transcription factor 4 (Oct4). It enhances the iPSC reprogramming efficiency and accelerates the reprogramming process.		OCT
T9588	JI130		Others
	JI130 is able to impair the ability of Hes1 to repress transcription. JI130 treatment significantly reduced tumor volume in a murine pancreatic tumor xenograft model.		Others
T4252	ML327		c-Myc , Autophagy
	ML327 is a MYC blocker. ML327 can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition (EMT).		c-Myc , Autophagy

Compounds

NFAT Transcription Factor Regulator-1

T12218

Synonym:

Target: IL Receptor

signal transducer and activator of transcription 6 fragment

Target: Epigenetic Reader Domain

ML-60218

T40661

Synonym:

Target: DNA/RNA Synthesis

Synonym: Baloxavir acid,S-033447

Target: Influenza Virus

CID 5951923

T22667

Synonym:

Target: DNA/RNA Synthesis

BMH-21

T1767

Synonym: BMH21

Target: DNA/RNA Synthesis

cjoc42

T27029

Synonym: cjoc 42,cjoc-42

Target: Others, Histone Methyltransferase

POL1-IN-1

T4356

Synonym: Compound 3A

Target: DNA/RNA Synthesis

Synonym: BRD-32048,BRD 32048

Target: DNA/RNA Synthesis

TK216

T13166

Synonym:

Target: Others, DNA/RNA Synthesis

Metarrestin

T12006

Synonym: ML246

Target: DNA/RNA Synthesis

Synonym: Triptycene-1,4-quinone

Target: Others, DNA/RNA Synthesis, CDK, HSV

8-Hydroxyquinoline hemisulfate

T7887

Synonym: Oxyquinoline sulfate

Target: Others, Antibacterial, Antibiotic

CCG-222740

T7764

Synonym:

Target: ROCK, Rho, Ras

XRP44X

T20759

Synonym: XRP-44-X,XRP 44X,XRP-44X,XRP 44 X

Target: Ras

GSK4112

T5045

Synonym: 1,1-Dimethylethyl-N-[(4-chlorophenyl)methyl]-N-[(5-nitro-2-thienyl)methyl])glycinate,SR6452

Target: Autophagy

Lersivirine

T7700

Synonym: Lersivirine(UK 453061),UK-453061

Target: HIV Protease, Reverse Transcriptase

IMT1

T8841

Synonym: Propanamide, N,N-dimethyl-2-[[4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-,LDC195943(IMT1)

Target: Others, DNA/RNA Synthesis, Mitochondrial Metabolism

Transcriptional Intermediary Factor 2 (TIF2) (740-753)

T40459

Synonym: Transcriptional Intermediary Factor 2 (TIF2) (740-753)

Target: DNA/RNA Synthesis

DW14800

T11131

Synonym:

Target: Histone Methyltransferase

iCRT3

T4302

Synonym:

Target: Apoptosis, Wnt/beta-catenin

HJC0152 hydrochloride

T4234

Synonym: HJC0152

Target: Apoptosis, STAT

Target: Hedgehog/Smoothened

OAC3

T21813

Synonym: 4-fluoro-N-(1H-indol-5-yl)benzamide

Synonym: Xanthothricin,PKF-118-310,Toxoflavine

Target: Wnt/beta-catenin, Antibacterial, Antibiotic

CCG-1423

T2014

Synonym: CCG1423

Target: LRRK2, Rho, Ras

Synonym: AT-4140,PD 131501,Zagam,CI-978

Target: DNA gyrase, Topoisomerase, Antibacterial, Antibiotic

Target: Hedgehog/Smoothened, Smo

ICG-001

T6113

Synonym:

Target: Apoptosis, Epigenetic Reader Domain, Wnt/beta-catenin

Synonym: CINPA-1,CINPA 1

Target: Others

Ro24-7429

T28578

Synonym: Ro 24-7429,Ro-24-7429,Ro 247429

Synonym: BAS 00287861

Target: c-Myc, Autophagy

カタログ番号	製品名	別名	ターゲット
T5689	20-DEOXYINGENOL		Others , Autophagy
	20-DEOXYINGENOL is a natual product.		Others , Autophagy
T13502	3-Oxo-5β-cholanoic acid	Dehydrolithocholic acid	ROR
			ROR
T4972	2'-Deoxycytidine-5'-diphosphate trisodium	dCDP	Endogenous Metabolite
	2'-Deoxycytidine-5'-diphosphate trisodium (dCDP) is used as a substrate of CDP (nucleoside diphosphate) kinase (2.7.4.6) for the production of dCTP to support DNA biosynthesis and reverse transcription.		Endogenous Metabolite
T6S1141	Ganoderic acid A		Apoptosis , NF-κB , Endogenous Metabolite , Autophagy
	1. Ganoderic acid A exhibits antitumor activity, mediated through its inhibitory effect on nuclear transcription factor-kappaB and activator protein-1. 2. Ganoderic acid A can induce proliferation inhibition, apoptosis a...		Apoptosis , NF-κB , Endogenous Metabolite , Autophagy
TN1836	Kudinoside D		LDL , AMPK , PPAR
	Kudinoside D exerts anti-adipogenic effects through modulation of adipogenic transcription factors via AMPK signaling pathway.		LDL , AMPK , PPAR
T79972	Cyclo(L-leucyl-L-valyl)
	Cyclo(L-leucyl-L-valyl) suppresses Aflatoxin biosynthesis in Aspergillus parasiticus by inhibiting the transcription of Aflatoxin-associated genes, including aflR, hexB, pksL1, and dmtA.[1]
T3384	Wedelolactone	IKK Inhibitor II	Apoptosis , NF-κB , Lipoxygenase , Caspase
	Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.		Apoptosis , NF-κB , Lipoxygenase , Caspase
T2896	Alantolactone	helenin,Eupatal,Helenine,(+)-Alantolactone,Alant camphor,Inula camphor	Apoptosis , STAT , TGF-beta/Smad
	Alantolactone (Inula camphor)(Alant camphor), a sesquiterpene lactone, has potential activity against triple-negative breast Y MDA-MB-231 cells by suppressing the signal transducer and activator of transcription 3 (STAT3...		Apoptosis , STAT , TGF-beta/Smad
TN1273	7,4'-Dihydroxyflavone	4',7-Dihydroxyflavone	NF-κB , COX , HDAC , CCR , NOD
	7,4'-Dihydroxyflavone (4',7-Dihydroxyflavone) can induce transcription of nodulation (nod) genes in Rhizobium meliloti. It has inhibitory activities against COX-2.		NF-κB , COX , HDAC , CCR , NOD
T1168	Desonide	Tridesilon,Locapred,Prednacinolone	Glucocorticoid Receptor
	Desonide (Prednacinolone) is a synthetic glucocorticosteroid for topical use, with anti-inflammatory activity. Desonide binds to glucocorticoid receptors in the cytoplasm, and the ligand-receptor complex is translocated ...		Glucocorticoid Receptor
TN2121	3,5,7,3′,4′-Pentamethoxyflavone	Quercetin 3,5,7,3,4-pentamethyl ether	Others
	3,5,7,3′,4′-Pentamethoxyflavone (Quercetin 3,5,7,3,4-pentamethyl ether) is a natural product. It can induce adipogenesis on 3T3-L1 preadipocytes by regulating transcription factors at an early stage of differentiation.		Others
TN1664	Ganoderic acid H		NF-κB , DNA/RNA Synthesis , CDK
	Ganoderic acid H is a potent antitumour agent, it mediates its biological effects through the inhibition of transcription factors AP-1 and NF-kappaB, resulting in the down-regulation of expression of Cdk4.		NF-κB , DNA/RNA Synthesis , CDK
TN6393	Fulvotomentoside A		Others
	Fulvotomentoside A could decrease overexpression of IL-6 and IL-17A, and increase the expression of specific transcription factor Foxp3 of regulatory T cells significantly in intestine. It may be one of the mechanisms th...		Others
T5770	Alisol B		RANKL/RANK
	Alisol B may be a potential novel therapeutic molecule for bone disorders through targeting the differentiation of osteoclasts as well as their functions. Alisol B also inhibited RANKL-induced expression of NFATc1 and c-...		RANKL/RANK
T2336	Vitamin K2	Menatetrenone	Endogenous Metabolite
	Vitamin K2 (Menatetrenone) is a menaquinone compound and form of vitamin K2 with potential antineoplastic activity. Menatetrenone may act by modulating the signaling of certain tyrosine kinases, thereby affecting several...		Endogenous Metabolite
T5S0734	Desmethoxyyangonin	Desmethoxy yangonin,Demethoxyyangonin,5,6-Dehydrokavain	Others , Monoamine Oxidase
	1. Desmethoxyyangonin (5,6-Dehydrokavain) protects LPS or LPS/D-GalN-induced damages in cell or liver tissues mainly through de-regulating IKK/NFκB and Jak2/STAT3 signaling pathways. 2. The induction of CYP3A23 by dihydr...		Others , Monoamine Oxidase
TN1163	2'-Hydroxychalcone		Others
	2'-Hydroxychalcone is a drug synthesis intermediate for the synthesis of flavonoids. 2'-Hydroxychalcone loaded in nanoemulsion showed fungicidal activity against Coccidioides parapsilosis in Danio rerio model.2'-Hydroxyc...		Others
T10086	24-Hydroxycholesterol	Cholest-5-ene-3beta,24-diol	Liver X Receptor , NMDAR
	24-Hydroxycholesterol (Cholest-5-ene-3beta,24-diol) is an oxysterol compound that is an activator of the n-methyl-d-aspartate receptor (NMDA) and the transcription factor LXR, which has been used in the study of cardioge...		Liver X Receptor , NMDAR
T3363	Jervine	Iervin,11-Ketocyclopamine,Jerwiny	Hedgehog/Smoothened , Smo
	The biological activity of Jervine (Jerwiny) is mediated via its interaction with the 7 passes transmembrane protein Smoothened. Jervine binds with and inhibits smoothened, which is an integral part of the Hedgehog signa...		Hedgehog/Smoothened , Smo
T5530	Mithramycin A	Plicamycin	DNA/RNA Synthesis
	Mithramycin A (Plicamycin), a DNA-binding antitumor antibiotic, is a selective specificity protein 1 (Sp1) inhibitor, which inhibits the growth of various cancers by decreasing Sp1 protein. Specificity protein 1 (Sp1) is...		DNA/RNA Synthesis
T20879	Tacrolimus monohydrate	FK-506,FR 900506,Prograf,FR900506,Tacrolimus hydrate,LCP-Tacro,FK 506	Phosphatase , Others , Antibacterial , Antibiotic , Autophagy
	Tacrolimus monohydrate (LCP-Tacro) is a macrolide from the culture broth of a strain of Streptomyces tsukubaensis, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, whi...
T2S1837	Steviol	NSC 226902,Hydroxydehydrostevic acid	Others
	1. Steviol (NSC-226902), a natural sweetener, it inhibits proliferation of the gastrointestinal cancer cells intensively. 2. Steviol can induce a significant increase in CYP3A29 expression. 3. Steviol inhibits the prolif...		Others
TN1237	3-O-Methylgallic acid	3,4-Dihydroxy-5-methoxybenzoic acid	Apoptosis , NF-κB , OCT , DNA/RNA Synthesis , STAT
	3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) reduces cell proliferation in Caco-2 cells(IC50 = 24.1 μM) more effectively than anthocyanins and may offer protection against colon cancer after its formation ...		Apoptosis , NF-κB , OCT , DNA/RNA Synthesis , STAT
T4010	Juglone	5-Hydroxy-1,4-naphthoquinone,Regianin	DNA/RNA Synthesis , Antibacterial
	Juglone (Regianin) is a natural naphthoquinone found in the black walnut (J. nigra) and other plants in the Juglandaceae family. Juglone also irreversibly inhibits peptidyl-prolyl cis/trans isomerases of the parvulin fam...		DNA/RNA Synthesis , Antibacterial
T0034	Cortisone acetate	Cortisone 21-acetate,NSC 49420	Glucocorticoid Receptor , Endogenous Metabolite
	Cortisone Acetate is a synthetic or semisynthetic analog of the naturally occurring cortisone hormone produced by the adrenal glands with anti-inflammatory and immunomodulating properties. Cortisone acetate (NSC-49420) d...		Glucocorticoid Receptor , Endogenous Metabolite
T2823	Crocin	Gardenia Yellow,Alpha-Crocin	Others
	Crocin (Gardenia Yellow) is a water-soluble carotenoid pigment of saffron (Crocus sativus L. ) that has been used as a spice for flavoring and coloring food preparations, and in Chinese traditional medicine as an anodyne...		Others
T1611	Isotretinoin	13-cis-Retinoic acid	Retinoid Receptor , Endogenous Metabolite , Autophagy
	Isotretinoin (13-cis-Retinoic acid) binds to and activates nuclear retinoic acid receptors (RARs); activated RARs serve as transcription factors that promote cell differentiation and apoptosis. Isotretinoin is a naturall...		Retinoid Receptor , Endogenous Metabolite , Autophagy
T6429	Caffeic Acid Phenethyl Ester	Phenylethyl Caffeate,CAPE	Apoptosis , NF-κB
	Caffeic Acid Phenethyl Ester (Phenylethyl Caffeate) (CAPE) inhibits the activation of nuclear transcription factor NF-kappa B and may suppress p70S6K and Akt-driven signaling pathways, with antineoplastic, cytoprotective...		Apoptosis , NF-κB
T1719	Bufalin		ATPase
	Bufalin is an active ingredient and one of the glycosides in the traditional Chinese medicine ChanSu; it is also a bufadienolide toxin originally isolated from the venom of the Chinese toad Bufo gargarizans, with potenti...		ATPase
T4S0878	Prunetin	Prunusetin	ERK , Dehydrogenase , NF-κB
	1. Prunetin (Prunusetin) significantly reduces serum levels of inflammatory cytokines and mortality in mice challenged with lipopolysaccharide. 2. Prunetin mediates anti-obesity/adipogenesis effects by suppressing obesit...		ERK , Dehydrogenase , NF-κB
T6S1315	Oroxylin A	6-Methoxybaicalein,Baicalein 6-methyl ether	Virus Protease , HIF/HIF Prolyl-Hydroxylase , Autophagy
	1. Oroxylin A (Baicalein 6-methyl ether) has various anti-tumor effects including apoptosis, cell cycle arrest, drug-resistant reversion. 2. Oroxylin A possesses abilities of inhibiting the ATRA-induced IL-6 production v...		Virus Protease , HIF/HIF Prolyl-Hydroxylase , Autophagy
T2S0843	Negletein	7-O-Methylbaicalein,Baicalein-7-methylether	IL Receptor , TNF , NOS , Interleukin
	1. Negletein (7-O-Methylbaicalein) has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β. 2. Negletein as a neuroprotectant enhances the action of nerve growth factor and induces n...		IL Receptor , TNF , NOS , Interleukin
TN5364	Boscialin
	Boscialin can inhibit signal transducer and activator of transcription 1 translocation at a concentration of 10 uM.
TN2249	(+)-Syringaresinol		Sirtuin , Antifection
	(+)-Syringaresinol shows antioxidant potential, it exhibits cytoprotective activity in cultured MCF-7 cells stressed by H2O2.		Sirtuin , Antifection
T13577	β-Zearalenol		Others
	β-Zearalenol, a non-steroidal estrogenic mycotoxin synthesized by Fusarium species, potentially influences transcription and affects gene expression on the translational level.		Others
T19463	N4-Acetylcytidine triphosphate	ac4CTP	Others
	N4-Acetylcytidine triphosphate is efficiently used as a substrate in T7 Polymerase-catalyzed in vitro transcription .		Others
T68731	Myxothiazol
	Myxothiazol is an inhibitor of mitochondrial respiratory chain complexes III. Myxothiazol induces transcription of the p53-responsive SESN2 gene that plays an important role in stress response and homeostatic regulation.
T19462	N4-Acetylcytidine triphosphate sodium	ac4CTP sodium	Others
	N4-Acetylcytidine triphosphate sodium is efficiently used as a substrate in T7 Polymerase-catalyzed in vitro transcription.		Others
TN1504	Citreorosein		cAMP , NF-κB , PI3K
	Citreorosein is a cAMP phosphodiesterase inhibitor, it has anti-inflammatory effect, inhibits proinflammatory cytokines production through the inhibition of both MAPKs and AKT-mediated IκB kinase (IKK) phosphorylation an...		cAMP , NF-κB , PI3K
TN2228	Soyasaponin Aa		PPAR
	Soyasaponin Aa and soyasaponin Ab dose-dependently markedly inhibit adipocyte differentiation and expression of various adipogenic marker genes, through the downregulation of the adipogenesis-related transcription factor...		PPAR
T13762	Luteolin 7-sulfate		Others
	Luteolin 7-sulfate, derived from the marine plant Phyllospadix iwatensis Makino, suppresses TYR gene expression by intervening in a signaling pathway involving the cAMP-responsive element binding protein (CREB) and micro...		Others
T74203	Licoagrochalcone C
	Licoagrochalcone C, a flavonoid compound, demonstrates potent inhibitory effects on NF-κB transcription and significantly reduces LPS-induced NO production, showcasing its bioactive properties [1] [2].
T75666	Mogroside VI B
	Mogroside VI B, a cucurbitane glucoside derived from Siraitia grosvenorii crude extract, exhibits potency in activating PGC-1α transcription [1].
T15467	Helenalin		Others
	Helenalin is a selective inhibitor of transcription factor NF-κB by direct targeting of p65. It is an anti-inflammatory sesquiterpene lactone compound with alkylating activity. Through its ability to target the cysteine ...		Others
T71896	Brevicompanine B
	Brevicompanine B is a fungal metabolite that has plant growth and circadian rhythm regulatory activity. Brevicompanine B inhibits primary root growth in Arabidopsis seedlings and disrupts the transcription of various gen...
TN3410	Anatabine		Beta Amyloid , IL Receptor , TNF , NF-κB , BACE , COX , STAT
	Anatabine shows anti-inflammatory activity in vitro and in vivo, which is mediated in part via an inhibition of STAT3 phosphorylation.Anatabine has anti-Alzheimer's disease effects, it inhibits BACE-1 transcription and r...
TN1862	Licoflavonol		Antifection
	Licoflavonol is a novel natural inhibitor of Salmonella T3SS, could be a promising candidate for novel type of anti-virulence drugs, it exhibits a strong inhibitory effect on the secretion of the SPI-1 effector proteins ...		Antifection
TN4490	Manassantin B		ERK , BCL , p38 MAPK , TNF , NF-κB , JNK , STAT , Antifection
	Manassantin B is a potent inhibitor of NF-ÎºB activation by the suppression of transciptional activity of RelA/p65 subunit of NF-ÎºB. It also possesses anti-EBV lytic replication activity. Manassantin B inhibits interleu...
TN4092	Galanolactone		5-HT Receptor
	Galanolactone has anti-5-HT effect, a diterpenoid isolated from ginger, is related to antagonism of 5-HT3 receptors, it has inhibit nitric oxide production with IC(50) values ranging from 5.5 to 28.5 μM. Galanolactone ex...		5-HT Receptor
TN5369	Dehydroleucodine	Dehydroleucodin
	Dehydroleucodine has antidiarrheal, anti-inflammatory, anti-microbial, embryotoxicity, gastric cytoprotective, anti-cancer activities. Dehydroleucodine has an important inhibitory effect in cellular pathways regulating a...
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天然物製品

20-DEOXYINGENOL

T5689

Synonym:

Target: Others, Autophagy

3-Oxo-5β-cholanoic acid

T13502

Synonym: Dehydrolithocholic acid

Target: ROR

2'-Deoxycytidine-5'-diphosphate trisodium

T4972

Synonym: dCDP

Target: Endogenous Metabolite

Ganoderic acid A

T6S1141

Synonym:

Target: Apoptosis, NF-κB, Endogenous Metabolite, Autophagy

Kudinoside D

TN1836

Synonym:

Target: LDL, AMPK, PPAR

Cyclo(L-leucyl-L-valyl)

Synonym: IKK Inhibitor II

Target: Apoptosis, NF-κB, Lipoxygenase, Caspase

Alantolactone

T2896

Synonym: helenin,Eupatal,Helenine,(+)-Alantolactone,Alant camphor,Inula camphor

Target: Apoptosis, STAT, TGF-beta/Smad

7,4'-Dihydroxyflavone

TN1273

Synonym: 4',7-Dihydroxyflavone

Target: NF-κB, COX, HDAC, CCR, NOD

Desonide

T1168

Synonym: Tridesilon,Locapred,Prednacinolone

Target: Glucocorticoid Receptor

3,5,7,3′,4′-Pentamethoxyflavone

TN2121

Synonym: Quercetin 3,5,7,3,4-pentamethyl ether

Target: NF-κB, DNA/RNA Synthesis, CDK

Synonym: Menatetrenone

Target: Endogenous Metabolite

Desmethoxyyangonin

T5S0734

Synonym: Desmethoxy yangonin,Demethoxyyangonin,5,6-Dehydrokavain

Target: Others, Monoamine Oxidase

24-Hydroxycholesterol

T10086

Synonym: Cholest-5-ene-3beta,24-diol

Target: Liver X Receptor, NMDAR

Jervine

T3363

Synonym: Iervin,11-Ketocyclopamine,Jerwiny

Target: Hedgehog/Smoothened, Smo

Mithramycin A

T5530

Synonym: Plicamycin

Target: DNA/RNA Synthesis

Tacrolimus monohydrate

T20879

Synonym: FK-506,FR 900506,Prograf,FR900506,Tacrolimus hydrate,LCP-Tacro,FK 506

Target: Phosphatase, Others, Antibacterial, Antibiotic, Autophagy

Steviol

T2S1837

Synonym: NSC 226902,Hydroxydehydrostevic acid

Target: Others

3-O-Methylgallic acid

TN1237

Synonym: 3,4-Dihydroxy-5-methoxybenzoic acid

Target: Apoptosis, NF-κB, OCT, DNA/RNA Synthesis, STAT

Juglone

T4010

Synonym: 5-Hydroxy-1,4-naphthoquinone,Regianin

Target: DNA/RNA Synthesis, Antibacterial

Cortisone acetate

T0034

Synonym: Cortisone 21-acetate,NSC 49420

Target: Glucocorticoid Receptor, Endogenous Metabolite

Crocin

T2823

Synonym: Gardenia Yellow,Alpha-Crocin

Target: Others

Isotretinoin

T1611

Synonym: 13-cis-Retinoic acid

Target: Retinoid Receptor, Endogenous Metabolite, Autophagy

Caffeic Acid Phenethyl Ester

T6429

Synonym: Phenylethyl Caffeate,CAPE

Target: Apoptosis, NF-κB

Target: ERK, Dehydrogenase, NF-κB

Oroxylin A

T6S1315

Synonym: 6-Methoxybaicalein,Baicalein 6-methyl ether

Target: Virus Protease, HIF/HIF Prolyl-Hydroxylase, Autophagy

Negletein

T2S0843

Synonym: 7-O-Methylbaicalein,Baicalein-7-methylether

Target: IL Receptor, TNF, NOS, Interleukin

Target: Sirtuin, Antifection

N4-Acetylcytidine triphosphate

N4-Acetylcytidine triphosphate sodium

T19462

Synonym: ac4CTP sodium

Target: cAMP, NF-κB, PI3K

Target: Beta Amyloid, IL Receptor, TNF, NF-κB, BACE, COX, STAT

Target: ERK, BCL, p38 MAPK, TNF, NF-κB, JNK, STAT, Antifection

Galanolactone

TN4092

Synonym:

Target: 5-HT Receptor

Dehydroleucodine

TN5369

Synonym: Dehydroleucodin

Target:

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-02603	STAT6 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Signal transducer and activator of transcription 6 (STAT6) is a transcription factor that is activated by interleukin-4 (IL-4)-induced tyrosine phosphorylation and mediates most of the IL-4-induced gene expression. STAT6...
TMPJ-00886	ATF1 Protein, Human, Recombinant (His)	Human	E. coli
	Cyclic AMP-dependent transcription factor ATF-1(ATF1) which contains 1 bZIP (basic-leucine zipper) domain and 1 KID (kinase-inducible) domain, belongs to the bZIP family. It influences cellular physiologic processes by r...
TMPY-03283	HBP1 Protein, Human, Recombinant (GST)	Human	E. coli
	HBP1 is a sequence-specific DNA-binding transcription factor. It is involved in many biological processes. It was reported that HBP1 binds to p16(INK4A) promoter and activates p16(INK4A) expression. We found that trichos...
TMPH-01164	ATF-3 Protein, Human, Recombinant (His)	Human	E. coli
	ATF3 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPJ-01067	TFIIB Protein, Human, Recombinant (GST)	Human	E. coli
	Transcription Initiation Factor IIB (TFIIB) is an essential factor for transcription by RNA Polymerase II. TFIIB localizes to the nucleus where it forms a complex (the DAB complex) with transcription factor IID and IIA. ...
TMPH-03274	ATF-4 Protein, Rat, Recombinant (His & Myc)	Rat	E. coli
	Transcription factor that binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') and displays two biological functions, as regulator of metabolic and redox processes under normal cellular conditions, an...
TMPH-02613	ATF-5 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Transcription factor that either stimulates or represses gene transcription through binding of different DNA regulatory elements such as cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), ATF5-specific respo...
TMPY-02072	HSF1 Protein, Human, Recombinant (His)	Human	E. coli
	Heat shock factor protein 1, also known as heat shock transcription factor 1, HSF1, and HSTF1, is a cytoplasm and nucleus protein that belongs to the HSF family. HSF1 is the major transcription factor of HSPs (heat shock...
TMPH-01799	Nucleolar transcription factor 1 Protein, Human, Recombinant (E. coli, His & SUMO)	Human	E. coli
	Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream...
TMPH-01798	Nucleolar transcription factor 1 Protein, Human, Recombinant (Cell-Free, His & SUMO)	Human	in vitro E. coli expression system
	Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream...
TMPJ-00961	STAT1 Protein, Human, Recombinant	Human	E. coli
	Signal Transducer and Activator of Transcription 1-Alpha/Beta (STAT1) contains one SH2 domain and belongs to the transcription factor STAT family. When tyrosine- and serine-phosphorylated, STAT1 can form a homodimer term...
TMPH-02609	CREBZF Protein, Mouse, Recombinant (His)	Mouse	Baculovirus
	Strongly activates transcription when bound to HCFC1. Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. Also suppresses the HCFC1-dependent transcriptional activation...
TMPJ-00904	NFYA Protein, Human, Recombinant (GST)	Human	E. coli
	Nuclear Transcription Factor Y Subunit α (NFYA) is a member of the NFYA/HAP2 subunit family. NFYA founctions as a heterotrimeric transcription factor , which is composed of three components, NF-YA, NF-YB and NF-YC, binds...
TMPJ-00903	NFYA Protein, Human, Recombinant	Human	E. coli
	Nuclear Transcription Factor Y Subunit α (NFYA) is a member of the NFYA/HAP2 subunit family. NFYA founctions as a heterotrimeric transcription factor , which is composed of three components, NF-YA, NF-YB and NF-YC, binds...
TMPJ-01003	STAT5B Protein, Human, Recombinant (His)	Human	E. coli
	Signal Transducer and Activator of Transcription 5b (STAT5B) is a member of the STAT family of transcription factors. They are responsible for an array of cellular activities including regulating growth, survival, differ...
TMPY-02581	STAT4 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	High expression of STAT4 in gastric cancer predicted a better clinical outcome. STAT4 might be a useful biomarker to identify patients at high risk of recurrence after gastrectomy. Genetic variants in the transcription f...
TMPU-00004	STAT5A Protein, Human, Recombinant (His)	Human	E. coli
	Signal transducer and activator of transcription 5A is a protein that in humans is encoded by the STAT5A gene. Many studies have indicated a key role of STAT5a in leukemia, breast, colon, head and neck, and prostate canc...
TMPJ-00914	YY1 Protein, Human, Recombinant (His)	Human	E. coli
	Transcriptional repressor protein YY1（YY1）contains 4 C2H2-type zinc fingers and belongs to the YY transcription factor family. Multifunctional transcription factor exhibits positive and negative control on a large number...
TMPY-02444	ATF2 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	Activating transcription factor 2, also known as ATF2, is a member of the leucine zipper family of DNA-binding proteins that binds to the cAMP response element. Its activity is enhanced after phosphorylation by stress-ac...
TMPY-02949	AP2 Gamma/TFAP2C Protein, Human, Recombinant (His)	Human	E. coli
	TFAP2C, also known as AP2-GAMMA, is a member of the activating protein 2 family of transcription factors. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of imp...
TMPY-06624	STAT3 Protein, Human, Recombinant (His)	Human	E. coli
	STAT3 Protein, Human, Recombinant (His) is expressed in E. coli with His tag. The predicted molecular weight is 65.31 kDa. Accession number: P40763-1
TMPJ-01080	HSF2 Protein, Human, Recombinant (His)	Human	E. coli
	Heat Shock Factor Protein 2 (HSF2) belongs to the HSF family of transcription factors that bind specifically to the heat-shock promoter element and activate transcription. In higher eukaryotes, HSF is unable to bind to t...
TMPY-02240	STAT1 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	STAT1 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor-associated kinases, and then form homo- or heterodimers that translocate t...
TMPH-00886	ATF7IP2 Protein, Human, Recombinant (His)	Human	E. coli
	Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the conte...
TMPJ-01121	MORF4L2 Protein, Human, Recombinant (His)	Human	E. coli
	Mortality Factor 4-Like Protein 2 (MORF4L2) is a member of the mortality factor (MORF) family. MORF4L2 localizes in the nucleus, possessing a protein kinase C phosphorylation site and a tyrosine phosphorylation site. MOR...
TMPY-01709	HIF-1 alpha Protein, Human, Recombinant (His)	Human	E. coli
	HIF-1 alpha, also known as HIF1A, contains 1 basic helix-loop-helix (bHLH) domain, 1 PAC (PAS-associated C-terminal) domain, and 2 PAS (PER-ARNT-SIM) domains. It is one of the two subunits of Hypoxia-inducible factor-1 (...
TMPH-01720	C-Myc Protein, Human, Recombinant (His)	Human	E. coli
	Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promotin...
TMPH-01721	C-Myc Protein, Human, Recombinant (Avi & His & MBP), Biotinylated	Human	E. coli
	Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promotin...
TMPH-02791	C-Myc Protein, Mouse, Recombinant (GST)	Mouse	E. coli
	c-Myc Protein, Mouse, Recombinant (GST) is expressed in E. coli.
TMPH-01173	CDK7 Protein, Human, Recombinant	Human	E. coli
	CDK7 Protein, Human, Recombinant is expressed in E. coli.
TMPJ-01288	KLF6 Protein, Human, Recombinant	Human	E. coli
	Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localizes in the nucleus. KLF6 expression is highest in the placenta followed by ...
TMPH-01172	CDK7 Protein, Human, Recombinant (His)	Human	Baculovirus
	CDK7 Protein, Human, Recombinant (His) is expressed in Baculovirus.
TMPJ-00778	HER2/ERBB2 Protein, Human, Recombinant (His)	Human	Human Cells
	Human epidermal growth factor receptor 2 (HER2) is a type of membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 plays a key role in development, cell proliferation and different...
TMPY-04632	IL-15 Protein, Human, Recombinant	Human	E. coli
	The protein encoded by the IL15 gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common h...
TMPY-05176	AMH Protein, Human, Recombinant (His)	Human	HEK293
	Anti-Mullerian hormone (AMH), a member of the TGF-beta superfamily, is produced by granulosa cells (GCs) of preantral and small antral follicles and plays a role in regulating the recruitment of primordial follicles and ...
TMPY-04548	CDK4 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	CDK4 is a member of the Ser/Thr protein kinase family. It is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cel...
TMPY-04781	LILRB1/CD85j/ILT2 Protein, Human, Recombinant (hFc)	Human	HEK293
	LILRB1 (Leukocyte Immunoglobulin Like Receptor B1) is a Protein Coding gene. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transme...
TMPY-02647	IFNAR1 Protein, Human, Recombinant (His)	Human	HEK293
	Interferon-alpha/beta receptor alpha chain (IFNAR1) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus prote...
TMPY-02575	PPAR gamma/PPARG Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	Peroxisome proliferator-activated receptor gamma (PPARG), a nuclear hormone receptor, plays a critical role in the lipid and glucose homeostasis, adipocyte differentiation, as well as intracellular insulin-signaling even...
TMPY-03995	LILRB1/CD85j/ILT2 Protein, Human, Recombinant (His)	Human	HEK293
	LILRB1 (Leukocyte Immunoglobulin Like Receptor B1) is a Protein Coding gene. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transme...
TMPY-04793	IL-35 Protein, Human, Recombinant (Flag & His)	Human	HEK293
	IL12A is a subunit of a cytokine that acts on T and natural killer cells and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, ...
TMPJ-00335	TGFBR2 Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Transforming growth factor-β (TGF-β) is an essential regulator in the processes of development, cell proliferation, and extracellular matrix deposition. TGF-β regulates cellular processes by binding to three high-affinit...
TMPY-00665	Aminopeptidase N/CD13 Protein, Human, Recombinant (I603M, His)	Human	HEK293
	Aminopeptidase N (ANPEP or APN), also known as CD13, is a cell-surface metalloprotease located in the small-intestinal and renal microvillar membrane, as well as other plasma membranes. It belongs to the peptidase M1 fam...
TMPJ-01210	IL-33 Protein, Mouse, Recombinant	Mouse	E. coli
	Mouse Interleukin 33 (IL-33) is a 30 kDa proinflammatory cytokine which may also regulates gene transcription in producer cells. IL-33 is constitutively expressed in smooth muscle and airway epithelia. IL-33 was identifi...
TMPY-02959	IL-20 Protein, Human, Recombinant	Human	E. coli
	IL20/Interleukin-20 belongs to the IL-10 family. It is a cytokine structurally related to interleukin 10. IL20/Interleukin-20 can be detected in skin, trachea, and other tissues. It is produced by activated keratinocytes...
TMPY-01003	TCN2 Protein, Human, Recombinant (His)	Human	HEK293
	Transcobalamin II, also known as TCN2 and TC II, is a plasma protein that binds cobalamin (Cbl; vitamin B12) as it is absorbed in the terminal ileum and distributes to tissues. The circulating transcobalamin II-cobalamin...
TMPJ-01466	Osteoprotegerin Protein, Human, Recombinant (aa 22-401, His)	Human	Human Cells
	TNFRSF11B is a secreted protein, containing 2 death domains and 4 TNFR-Cys repeats. TNFRSF11B is a decoy receptor for the receptor activator of nuclear factor kappa B ligand (RANKL). By binding RANKL, TNFRSF11B inhibits ...
TMPY-01478	HSP90 alpha Protein, Human, Recombinant	Human	E. coli
	Heat shock protein 90 (90 kDa heat-shock protein, HSP90) is a molecular chaperone involved in the trafficking of proteins in the cell. It is a remarkably versatile protein involved in the stress response and normal homoe...
TMPY-01459	TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with th...
TMPY-01871	IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His)	Human	HEK293
	Interleukin 5 receptor, alpha (IL5RA) also known as CD125 (Cluster of Differentiation 125) is a subunit of the Interleukin-5 receptor. IL5RA (CD125) is an interleukin 5 specific subunit of a heterodimeric cytokine recept...
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STAT6 Protein, Human, Recombinant (His)

TMPY-02603

Species: Human

Expression System: Baculovirus-Insect Cells

ATF1 Protein, Human, Recombinant (His)

TMPJ-00886

Species: Human

Expression System: E. coli

HBP1 Protein, Human, Recombinant (GST)

TMPY-03283

Species: Human

Expression System: E. coli

ATF-3 Protein, Human, Recombinant (His)

TMPH-01164

Species: Human

Expression System: E. coli

TFIIB Protein, Human, Recombinant (GST)

TMPJ-01067

Species: Human

Expression System: E. coli

ATF-4 Protein, Rat, Recombinant (His & Myc)

TMPH-03274

Species: Rat

Expression System: E. coli

ATF-5 Protein, Mouse, Recombinant (His & Myc)

TMPH-02613

Species: Mouse

Expression System: E. coli

HSF1 Protein, Human, Recombinant (His)

TMPY-02072

Species: Human

Expression System: E. coli

Nucleolar transcription factor 1 Protein, Human, Recombinant (E. coli, His & SUMO)

TMPH-01799

Species: Human

Expression System: E. coli

Nucleolar transcription factor 1 Protein, Human, Recombinant (Cell-Free, His & SUMO)

TMPH-01798

Species: Human

Expression System: in vitro E. coli expression system

STAT1 Protein, Human, Recombinant

TMPJ-00961

Species: Human

Expression System: E. coli

CREBZF Protein, Mouse, Recombinant (His)

TMPH-02609

Species: Mouse

Expression System: Baculovirus

NFYA Protein, Human, Recombinant (GST)

TMPJ-00904

Species: Human

Expression System: E. coli

NFYA Protein, Human, Recombinant

TMPJ-00903

Species: Human

Expression System: E. coli

STAT5B Protein, Human, Recombinant (His)

TMPJ-01003

Species: Human

Expression System: E. coli

STAT4 Protein, Human, Recombinant (His)

TMPY-02581

Species: Human

Expression System: Baculovirus-Insect Cells

STAT5A Protein, Human, Recombinant (His)

TMPU-00004

Species: Human

Expression System: E. coli

YY1 Protein, Human, Recombinant (His)

TMPJ-00914

Species: Human

Expression System: E. coli

ATF2 Protein, Human, Recombinant (His & GST)

TMPY-02444

Species: Human

Expression System: Baculovirus-Insect Cells

AP2 Gamma/TFAP2C Protein, Human, Recombinant (His)

TMPY-02949

Species: Human

Expression System: E. coli

STAT3 Protein, Human, Recombinant (His)

TMPY-06624

Species: Human

Expression System: E. coli

HSF2 Protein, Human, Recombinant (His)

TMPJ-01080

Species: Human

Expression System: E. coli

STAT1 Protein, Human, Recombinant (His & GST)

TMPY-02240

Species: Human

Expression System: Baculovirus-Insect Cells

ATF7IP2 Protein, Human, Recombinant (His)

TMPH-00886

Species: Human

Expression System: E. coli

MORF4L2 Protein, Human, Recombinant (His)

TMPJ-01121

Species: Human

Expression System: E. coli

HIF-1 alpha Protein, Human, Recombinant (His)

TMPY-01709

Species: Human

Expression System: E. coli

c-Myc Protein, Human, Recombinant (His)

TMPH-01720

Species: Human

Expression System: E. coli

c-Myc Protein, Human, Recombinant (Avi & His & MBP), Biotinylated

TMPH-01721

Species: Human

Expression System: E. coli

c-Myc Protein, Mouse, Recombinant (GST)

TMPH-02791

Species: Mouse

Expression System: E. coli

CDK7 Protein, Human, Recombinant

TMPH-01173

Species: Human

Expression System: E. coli

KLF6 Protein, Human, Recombinant

TMPJ-01288

Species: Human

Expression System: E. coli

CDK7 Protein, Human, Recombinant (His)

TMPH-01172

Species: Human

Expression System: Baculovirus

HER2/ERBB2 Protein, Human, Recombinant (His)

TMPJ-00778

Species: Human

Expression System: Human Cells

IL-15 Protein, Human, Recombinant

TMPY-04632

Species: Human

Expression System: E. coli

AMH Protein, Human, Recombinant (His)

TMPY-05176

Species: Human

Expression System: HEK293

CDK4 Protein, Human, Recombinant (GST)

TMPY-04548

Species: Human

Expression System: Baculovirus-Insect Cells

LILRB1/CD85j/ILT2 Protein, Human, Recombinant (hFc)

TMPY-04781

Species: Human

Expression System: HEK293

IFNAR1 Protein, Human, Recombinant (His)

TMPY-02647

Species: Human

Expression System: HEK293

PPAR gamma/PPARG Protein, Human, Recombinant (His & GST)

TMPY-02575

Species: Human

Expression System: Baculovirus-Insect Cells

LILRB1/CD85j/ILT2 Protein, Human, Recombinant (His)

TMPY-03995

Species: Human

Expression System: HEK293

IL-35 Protein, Human, Recombinant (Flag & His)

TMPY-04793

Species: Human

Expression System: HEK293

TGFBR2 Protein, Mouse, Recombinant (His)

TMPJ-00335

Species: Mouse

Expression System: Human Cells

Aminopeptidase N/CD13 Protein, Human, Recombinant (I603M, His)

TMPY-00665

Species: Human

Expression System: HEK293

IL-33 Protein, Mouse, Recombinant

TMPJ-01210

Species: Mouse

Expression System: E. coli

IL-20 Protein, Human, Recombinant

TMPY-02959

Species: Human

Expression System: E. coli

TCN2 Protein, Human, Recombinant (His)

TMPY-01003

Species: Human

Expression System: HEK293

Osteoprotegerin Protein, Human, Recombinant (aa 22-401, His)

TMPJ-01466

Species: Human

Expression System: Human Cells

HSP90 alpha Protein, Human, Recombinant

TMPY-01478

Species: Human

Expression System: E. coli

TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His)

TMPY-01459

Species: Human

Expression System: HEK293

IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His)

TMPY-01871

Species: Human

Expression System: HEK293

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カタログ番号	製品名
L1380	Transcription Factor-Targeted Compound Library	704 compounds
	Well-chosen 704 compounds with unique structures targeting transcription factor;
L1000	Approved Drug Library	2863 compounds
	A unique collection of 2863 approved drugs for high throughput screening (HTS) and high content screening (HCS);
L3700	JAK-STAT Compound Library	256 compounds
	A unique collection of 256 JAK/STAT signaling targeted compounds for high throughput and high content screening;
L3800	NF-κB Signaling Compound Library	740 compounds
	A unique collection of 740 compounds targeting NF-κB signaling for high throughput screening and high content screening;
L1510	Nuclear Receptor Compound Library	546 compounds
	A unique collection of 546 nuclear receptor signaling targeted compounds for high throughput and high content screening;
L1200	Epigenetics Compound Library	960 compounds
	Well-chosen 960 compounds related to epigenetic regulation for research in epigenetics, high throughput screening (HTS) and high content screening (HCS) for new drugs;
L8500	HIF-1 Signaling Pathway Compound Library	1352 compounds
	A unique collection of 1352 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies；
L4000	Bioactive Compound Library	14590 compounds
	A collection of 14590 small molecule compounds with validated activity for high throughput screening (HTS), high content screening (HCS), cell induction, and target identification;
L8300	Chromatin Modification Compound Library	256 compounds
	A unique collection of 256 compounds targeting chromatin remodeling pathway for high throughput screening (HTS) and high content screening (HCS);
L1300	PI3K-AKT-mTOR Compound Library	425 compounds
	A unique collection of 425 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved with PI3K/Akt/mTOR signaling;
L7200	Calcium Channel Compound Library	143 compounds
	A unique collection of 143 calcium channel blockers and agonists for high throughput and high content screening;
L1010	FDA-Approved & Pharmacopeia Drug Library	3158 compounds
	3158 compounds from marketed drugs for high throughput screening (HTS) and high content screening (HCS);