1525
347
2290
10
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
TP1144L | Corticotropin-releasing factor (human) acetate | Corticotropin-releasing factor (human) acetate (86784-80-7 Free base) | CRFR |
Corticotropin-releasing factor (human) acetate stimulates to synthesize and secret adrenocorticotropin in the anterior pituitary. | |||
T8679 | Epidermal Growth Factor | EGFR | |
Epidermal Growth Factor binds to epidermal growth factor receptor (EGFR) and stimulates cell growth and proliferation. It is approved for the treatment of diabetic foot ulcers. | |||
T38332 | Complement factor D-IN-2 | Complement System | |
Complement factor D-IN-2 is an inhibitor of Complement factor D and reduces the excessive activation of complement factor D. | |||
TP1106L | α-Factor Mating Pheromone, yeast acetate | Mating Factor α acetate,α-Factor Mating Pheromone, yeast acetate(59401-28-4 free base) | Others |
α-Factor Mating Pheromone, yeast acetate (Mating Factor α acetate) is a peptide of 13 amino acids secreted by Saccharomyces cerevisiae α cells. | |||
TP1155L | Human growth hormone-releasing factor acetate | GHSR | |
Human growth hormone-releasing factor acetate is a hypothalamic polypeptide and stimulates GH production and release by binding to the GHRH Receptor (GHRHR) on cells in the anterior pituitary[1]. | |||
T21723L | Epidermal Growth Factor Receptor Peptide Acetate | Epidermal Growth Factor Receptor Peptide Acetate(96249-43-3 Free base) | Others |
Epidermal Growth Factor Receptor Peptide Acetate (Epidermal Growth Factor Receptor Peptide Acetate(96249-43-3 Free base)) exists on the cell surface and is activated by the binding of its specific ligands.EGFR belongs t... | |||
T12218 | NFAT Transcription Factor Regulator-1 | IL Receptor | |
NFAT Transcription Factor Regulator-1 is an synthesis inhibitor of IL-2 (IC50 of 182 nM). | |||
T22774L | Eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species](TFA) | Others | |
eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species](TFA) is Elongation factor 1 subunit.eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) encodes an isoform of the alpha sub... | |||
T28869 | Streptomyces A-Factor | A-Factor (Lactone) | |
Streptomyces A-Factor is a microbial hormone found in Streptomyces griseus. A-factor triggers streptomycin biosynthesis and cell differentiation by binding a repressor-type receptor protein (ArpA) and dissociating it fro... | |||
T30743 | Carbon dioxide reduction factor | Methanofuran,Cdr factor | |
Carbon dioxide reduction factor is a coenzyme of methanogenesis from carbon dioxide. | |||
TP1144 | Corticotropin-releasing factor (human) | Human corticotropin-releasing factor,Human CRF,Corticotropin-releasing factor human | |
Corticotropin-releasing factor human (Human CRF; Human corticotropin-releasing factor) is an immunomodulatory neuropeptide that acts to release ACTH from the anterior pituitary and stimulates the sympathetic nervous syst... | |||
T38969 | Factor B-IN-1 | ||
Factor B-IN-1 is a Factor B inhibitor. | |||
T36523 | Extracellular Death Factor | ||
Programmed cell death in bacteria is dependent on a system of cell-to-cell communication termed quorum sensing. Extracellular death factor (EDF) is a linear pentapeptide that communicating cells produce and release, whic... | |||
T40459 | Transcriptional Intermediary Factor 2 (TIF2) (740-753) | Transcriptional Intermediary Factor 2 (TIF2) (740-753) | |
Transcriptional Intermediary Factor 2 (TIF2) (740-753) is a 14-amino acid peptide that serves as a coactivator of TIF-2 protein. It specifically covers residues 740-753 of the TIF-2 protein. | |||
TP1106 | α-Factor Mating Pheromone, yeast | Mating Factor α | |
Alpha factor mating pheromone is a peptide of 13 amino acids secreted by Saccharomyces cerevisiae α cells. | |||
T38803 | Factor D inhibitor 6 | ||
Factor D inhibitor 6 is a potent, highly selective, orally active compound that specifically inhibits the activity of factor D (FD). It demonstrates an IC50 of 30 nM and a Kd of 6 nM. Notably, Factor D inhibitor 6 does n... | |||
T37111 | Corticotropin-releasing factor (human) (acetate) | ||
Human CRF acetate is a chemical compound that effectively stimulates the synthesis and secretion of adrenocorticotropin in the anterior pituitary. | |||
TP1155 | Human growth hormone-releasing factor | Growth Hormone Releasing Factor human | |
Human growth hormone-releasing factor stimulates GH production and release by binding to the GHRH Receptor (GHRHR) on cells in the anterior pituitary.Growth hormone-releasing hormone is a hormone produced in the hypothal... | |||
TP1105 | α-Factor Mating Pheromone, yeast (TFA) | α-Factor Mating Pheromone, yeast (TFA)(59401-28-4,FREE),Mating Factor α (TFA) | |
The alpha factor pheromone arrests yeast in the G1 phase of their cell cycle. Alpha Factor Mating Pheromone induces the expression of mating genes, changes in nuclear architecture, and polarzes growth toward the mating p... | |||
T19750 | Spinosad Factor D | ||
Spinosad Factor D is a naturally derived fermentation product. It is used as a pesticide against many different insects. | |||
T41065 | Atrial natriuretic factor (1-28) (human, porcine) | Atrial natriuretic factor (1-28) (human, porcine),Atrial natriuretic peptide (1-28) | |
Atrial natriuretic factor (1-28) from both human and porcine sources is a powerful suppressor of pro-opiomelanocortin (POMC) mRNA, while it only has a modest inhibition effect on βEP-LI release. | |||
TP1030 | Thymus factor X | TFX-Jelfa | |
Thymic factor X (TFX-Jelfa) is an aqueous extract from the thymus of a juvenile calf and is a natural stimulator of lymphocyte function. | |||
T16898 | Complement factor D-IN-1 | Others | |
Complement factor D-IN-1 is an effective and selective small-molecule reversible factor d inhibitor (IC50s: 0.006 and 0.05 μM in FD Thioesterolytic Fluorescent Assay and a MAC Deposition Assay, respectively). | |||
TP2247 | Eukaryotic translation initiation factor 3 | Others | |
Eukaryotic initiation factors (eIF) are proteins involved in the initiation phase of eukaryotic translation. Eukaryotic translation initiation factor 3 binds to the ribosome subunit-mRNA complex. It has been implicated i... | |||
T80986 | Thymus Factor | ||
Thymus Factor is a crucial agent in the development of humoral immunity [1]. | |||
TP2466 | Platelet factor 4 (59-70) | PF4 (59-70) | |
Platelet factor 4 (59-70) elicits human neutrophil & monocyte chemotaxis. | |||
T31742 | Factor 390 A | F390-A,F390A,P-5-(S)-N-(N-(1-Oxo-2-(phosphonooxy)propyl)-L-gamma-glutamyl)-L-glutamate,F390 A | |
Factor 390 A is a phosphodiester between AMP & methanogen factor 420. | |||
T8680 | FIBROBLAST GROWTH FACTOR, BASIC, HUMAN | ||
FIBROBLAST GROWTH FACTOR, BASIC, HUMAN is a useful organic compound for research related to life sciences. The catalog number is T8680 and the CAS number is 62031-54-3. | |||
T125089 | Euphorbia factor L25 | ||
Euphorbia factor L25 is a useful organic compound for research related to life sciences and the catalog number is T125089. | |||
T126086 | Euphorbia factor L9 | ||
Euphorbia factor L9 is a useful organic compound for research related to life sciences and the catalog number is T126086. | |||
TP1667 | Platelet Factor 4 (58-70), human | ||
Platelet Factor 4 (58-70), human is a polypeptide based on the 58-70 amino acid sequence of Platelet Factor 4 (pf-4) residues. | |||
T80059 | Complement factor I | Endogenous Metabolite | |
Complement factor I, a serine protease, attenuates complement activity both in the fluid phase and on cell surfaces, working alongside cofactors such as factor H (FH), complement receptor 1 (CR1/CD35), C4 binding protein... | |||
T125686 | Euphorbia factor L22 | ||
Euphorbia factor L22 is a useful organic compound for research related to life sciences and the catalog number is T125686. | |||
T125685 | Euphorbia factor L24 | ||
Euphorbia factor L24 is a useful organic compound for research related to life sciences and the catalog number is T125685. | |||
T62688 | Factor B-IN-4 | ||
Factor B-IN-4 is a potent inhibitor (IC50: 1 μM) of complement factor B. Factor B-IN-4 can be used to study inflammatory and immune-related diseases. | |||
T62292 | Factor B-IN-2 | ||
Factor B-IN-2 is a potent inhibitor (IC50: 1.5 μM) of complement factor B. Factor B-IN-2 can be used to study inflammatory and immune-related diseases. | |||
T82458 | Epigenetic factor-IN-1 | Sirtuin | |
Epigenetic factor-IN-1 (40569Z) is an epigenetic factor inhibitor that exhibits potent binding affinity for SIRT7. It is utilized in the study of liver cancer [1]. | |||
T62276 | Factor B-IN-3 | ||
Factor B-IN-3 is a potent inhibitor of complement factor B. Factor B-IN-3 can be used to study inflammatory and immune-related diseases. | |||
T62689 | Factor B-IN-5 | ||
Factor B-IN-5 is a potent inhibitor (IC50: 1.2 μM) of complement factor B. Factor B-IN-4 can be used to study inflammatory and immune-related diseases. | |||
T60991 | Factor VII-IN-1 | ||
Factor VII-IN-1 (example 43) has anticoagulant activities that is a potent factor VII (FVII) inhibitor with an IC50 value of 1.1 μM [1]. | |||
T37819 | Brain-Derived Acidic Fibroblast Growth Factor (102-111) (bovine) (trifluoroacetate salt) | ||
Brain-derived acidic fibroblast growth factor (102-111) is a peptide fragment of brain-derived acidic fibroblast growth factor (aFGF). aFGF is an angiogenic vascular endothelial cell mitogen produced in bovine brain that... | |||
T37595 | Brain-Derived Acidic Fibroblast Growth Factor (1-11) (bovine) (trifluoroacetate salt) | ||
Brain-derived acidic fibroblast growth factor (brain-derived aFGF) (1-11) is a peptide fragment of brain-derived aFGF. Brain-derived aFGF is an angiogenic vascular endothelial cell mitogen produced in bovine brain that h... | |||
T37820 | Brain-Derived Basic Fibroblast Growth Factor (1-24) (bovine) (trifluoroacetate salt) | ||
Brain-derived basic fibroblast growth factor (1-24) (brain-derived bFGF) is a peptide fragment of brain-derived bFGF. bFGF is a peptide produced in bovine brain that is protective in a rat model of pressure-induced retin... | |||
TP2229 | Epidermal growth factor receptor (994-1002) acetyl/amide | Others | |
The epidermal growth factor receptor is the cell-surface receptor for members of the epidermal growth factor family of extracellular protein ligands. | |||
T63234 | Factor XI-IN-1 | ||
Factor XI-IN-1 is an inhibitor of factor XI activation (EC50: 25.14 nM). | |||
TP1218 | Atrial natriuretic factor (1-28) (rat) TFA | Atrial Natriuretic Peptide (ANP) (1-28), rat TFA | |
Atrial Natriuretic Peptide (ANP) (1-28),rat (TFA) is the main circulating forms of Atrial Natriuretic Peptide (ANP) in rats, which strongly inhibit the secretion of Ang II - stimulated endothelin-1. | |||
T83484 | [Tyr0] Corticotropin Releasing Factor, ovine | ||
[Tyr^0] Corticotropin Releasing Factor, ovine, is a hypothalamic hormone sourced from sheep that prompts the secretion of adrenocorticotropic hormone (ACTH) and β-endorphin [1] [2]. | |||
T60491 | Elongation factor P-IN-1 | ||
Elongation factor P-IN-1 is a potent elongation factor P (EFP) inhibitor that is a β-lysine derivative compound. Elongation factor P-IN-1 affects E. coli proliferation rate[1]. | |||
T60682 | Elongation factor P-IN-2 | ||
Elongation factor P-IN-2 is a β-lysine derivative compound which is a potent elongation factor P (EFP) inhibitor. Elongation factor P-IN-2 affects the E. coli proliferation rates [1]. | |||
T76418 | Mating Factor α (1-6) | ||
Mating Factor α (1-6), a compound secreted by α-mating type cells of Saccharomyces cerevisiae, functions as an inhibitor of DNA synthesis initiation in these cells [1]. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
TN1635 | Euphorbia factor L8 | Others | |
Euphorbia factor L8 is a natural product | |||
TN1634 | Euphorbia factor L7b | Others | |
Euphorbia factor L7b,a natural product obtained from the herbs of Euphorbia pekinensis Rupr. | |||
T2S0410 | Euphorbia factor L1 | Euphorbiasteroid | Apoptosis , P-gp |
Euphorbia factor L1 (Euphorbiasteroid) can reduce Bcl-2, PI3K, AKT, and mTOR protein and mRNA levels, and up-regulate caspase-9 and caspase-3 protein levels. It induces autophagy and has anti-cancer, anti-adipogenic, ant... | |||
T5798 | Euphorbia Factor L2 | euphorbiafactor L2 | Apoptosis , NF-κB |
Euphorbia Factor L2 alleviates lipopolysaccharide-induced acute lung injury and inflammation through inhibits NF-κB activation. | |||
T125211 | Deoxy euphorbia factor L1 | Others | |
Deoxy euphorbia factor L1 is a natural product found in the seeds of Euphorbia lathyris L | |||
T78500 | α-Factor Mating Pheromone, yeast TFA | Mating Factor α TFA | |
α-Factor Mating Pheromone (yeast TFA) is a tridecapeptide secreted by Saccharomyces cerevisiae α cells and interacts with the Ste2p receptor [1]. | |||
TN1633 | Euphorbia factor L7a | Others | |
Euphorbia factor L7a is a natural product | |||
TQ0099 | 20-O-Acetylingenol-3-angelate | Euphorbia factor Pe1 | Others |
20-O-Acetylingenol-3-angelate (Euphorbia factor Pe1) is a natural compound found in the leaves and stems of the plant Inga. It has a variety of biological activities including tumor growth inhibition, anti-inflammatory, ... | |||
T3220 | Euphorbiasteroid | Euphobiasteroid,Euphorbia factor L1 | Others , AMPK |
Euphorbiasteroid (Euphobiasteroid) (25-50 μM) decreased differentiation of 3T3-L1 cells via reduction of intracellular triglyceride (TG) accumulation. | |||
T4S2014 | 5,15-Diacetyl-3-benzoyllathyrol | Euphorbia factor L3 | Others |
1. 5,15-Diacetyl-3-benzoyllathyrol (Euphorbia factor L3) is a melanine production inhibitor, excellent in inhibiting pigment stagnation and improving the discoloration of the skin or freckles, has excellent stability. | |||
T1255 | Tobramycin | NSC 180514,Nebramycin Factor 6,Deoxykanamycin B | ribosome , Antibacterial , Antibiotic |
Tobramycin (NSC-180514) is an aminoglycoside, broad-spectrum antibiotic produced by Streptomyces tenebrarius. | |||
T4S0217 | HOMOPLANTAGININ | TNF , NF-κB | |
Homoplantaginin is a flavonoid from a traditional Chinese medicine Salvia plebeia,it has a protective and therapeutic effect on hepatocyte injury and shows potent inhibitory activities against influenza. | |||
T10383 | Asatone | NF-κB | |
Asatone, an active component isolated from Radix et Rhizoma Asari, has an anti-inflammatory effect via activation of NF-κB and downregulation of p-MAPK (ERK, JNK, and p38) pathways. | |||
T4S1540 | Myrislignan | Apoptosis , NF-κB | |
Myrislignan has anti-inflammatory, and anti-cancer activities, it inhibited NF-κB signalling pathway activation, inhibited the proliferation of A549 cells in a dose- and time-dependent manner, it also significantly induc... | |||
TN1131 | Handelin | NF-κB , Immunology/Inflammation related | |
Handelin has anti-inflammatory activity by inhibiting NF-κB activation and pro-inflammatory cytokine productions. | |||
T5688 | Micheliolide | NOS , NF-κB , COX | |
Micheliolide(MCL) is a sesquiterpene lactone which inhibits various inflammatory response. | |||
T13686 | Ergolide | NF-κB | |
Ergolide, a sesquiterpene lactone extracted from the dried flowers of Inula Britannica, effectively hinders the expression of inducible nitric oxide synthase and cyclo-oxygenase-2 in RAW 264.7 macrophages by deactivating... | |||
T3S1641 | Esculentoside H | TNF , NF-κB , JNK | |
Phytolaccaceae has anti-tumor activity, the mechanism may be related to the capacity of Esculentoside H for TNF release. | |||
T3S0807 | Berbamine | CaMK , NF-κB , Autophagy | |
Berbamine is a natural product extracted from Phellodendron amurense. It acts as a calcium channel blocker and possesses anti-tumor, immunomodulatory, and cardiovascular effects. | |||
T3251 | Stachydrine Hydrochloride | NF-κB | |
Stachydrine Hydrochloride is an effective component that mainly extracted from the leaf of Leonurussibiricus. | |||
T6S0119 | Dauricine | Apoptosis , Others , NF-κB | |
1. Dauricine has pulmonary toxicity, can produce pulmonary injury in CD-1 mice by the metabolism of Dauricine mediated by CYP3A. 2. Dauricinec can pass the blood-brain barrier, and that P-glycoprotein has an important ro... | |||
TMA0507 | Tomatidine | NF-κB , JNK , Autophagy | |
Tomatidine serves as an anti-inflammatory agent by inhibiting NF-κB and JNK signaling pathways. Additionally, it induces autophagy in both mammalian cells and C. elegans. | |||
TN2008 | Okanin | NF-κB , TLR | |
Okanin shows significant activities on both linoleic acid peroxidation inhibition and DPPH radical scavenging effect. | |||
T3S1707 | Dendrophenol | Moscatilin | NF-κB |
Dendrophenol (Moscatilin) is a natural product isolated from the stem of Dendrobium loddigesii Rolfe, act as a NF-κB inhibitor. Antineoplastic activity. | |||
T5S2129 | Sciadopitysin | TNF , NF-κB | |
Sciadopitysin may prevent the development of diabetic osteopathy, it exerts its therapeutic effects via upregulation of mitochondrial biogenesis.Sciadopitysin shows protective effects on antimycin A-induced toxicity in o... | |||
T16324 | Nimbolide | Apoptosis , NF-κB , CDK | |
Nimbolide suppresses CDK4/CDK6 kinase activity. Nimbolide inhibits the NF-κB, Wnt, PI3K-Akt, MAPK, and JAK-STAT signaling pathways. Nimbolide causes apoptosis through the inactivation of NF-κB. Nimbolide is a triterpene ... | |||
T5795 | Suberosin | Others , NF-κB | |
Suberosin exhibits anti-inflammatory, and anticoagulant activities, it also shows biting deterrent activity against Aedes aegypti, it may be useful for use as mosquito larvicidal agent. | |||
T3877 | Esculentoside A | NF-κB , COX | |
Esculentoside A can suppress inflammatory responses in LPS-induced ALI through inhibition of the NF-κB and mitogen-activated protein kinase signaling pathways. Esculentoside A may be useful for the treatment of autoimmun... | |||
TL0016 | Sulforaphene | Apoptosis , ERK , EGFR , NF-κB | |
Sulforaphene is a natural product isolated from radish seeds, exhibits an ED50 against velvetleaf seedlings approximately 2 x 10 -4 M. Sulforaphene promotes cancer cells apoptosis and inhibits migration via inhibiting EG... | |||
T3893 | Forsythoside B | TNF , NF-κB | |
Forsythoside B binds to LPS and reduces the biological activity of serum LPS, and inhibits NF-κB activation. Forsythoside B inhibits the inflammatory response and has antioxidant properties. Potent neuroprotective effect... | |||
T3913 | Saikosaponin D | Estrogen Receptor/ERR , NF-κB , Antibacterial , STAT | |
Saikosaponin D is a novel SERCA inhibitor by inhibiting NF-κB and STAT3 signaling to protect against acetaminophen-induced hepatotoxicity. | |||
T11060 | DMAPT | Dimethylamino Parthenolide | NF-κB |
DMAPT (Dimethylamino Parthenolide) is a water-soluble analogue of Parthenolide (PTL). It is an orally active NF-κB inhibitor with an LD50 of 1.7 μM on primary acute myeloid leukemia cells. | |||
T4S0800 | Demethyleneberberine | P450 , NOS , NF-κB , HIF , AMPK | |
Demethyleneberberine, which is composed of a potential antioxidant structure, could penetrate the membrane of mitochondria and accumulate in mitochondria either in vitro or in vivo.Demethyleneberberine suppresses CYP2E1,... | |||
T4S1881 | Aconine | Jesaconine | Others , NF-κB |
1. Aconine (Jesaconine) is the febrifuge. 2. Aconine possesses gastric anaesthetic props. | |||
TN1079 | Deoxyelephantopin | NF-κB | |
Deoxyelephantopin has anti-inflammatory, hepatoprotective, and wound healing activities; it also has antitumor activity.Deoxyelephantopin inhibits NF-κB, MAPK, PI3K/Akt, and β-catenin signaling | |||
TN1712 | Gossypin | NF-κB , S6 Kinase | |
Gossypin has antidiabetic, antioxdiant, anticonvulsant, anti-allergic, antiinflammatory, antinociceptive, cytotoxic and antibacterial activities; it inhibits the NF-kappaB activation pathway, which may explain its role i... | |||
T6718 | Zingerone | Gingerone,Vanillylacetone,NSC 15335 | NF-κB |
Zingerone (Vanillylacetone) is a nontoxic methoxyphenol isolated from Zingiber officinale, with potent anti-inflammatory, antidiabetic, antidiarrhoeic, antilipolytic, antispasmodic and anti-tumor properties. Zingerone(Gi... | |||
T5S1607 | Morusin | Mulberrochromene | NF-κB , Antibacterial , STAT |
1. Morusin (Mulberrochromene) possesses antitumor effects of cell lines including HT-29, A549, MCF-7, and MDA-MB-231, through suppressing STAT3 and NFκB attenuation mediated apoptosis induction. 2. Morusin possesses anti... | |||
T5834 | Myrcene | Others | |
Myrcene is a terpene that has been found in Cannabis and has antioxidative properties. | |||
TQ0131 | Rocaglamide | Rocaglamide A,Roc-A | HSP , NF-κB , PERK |
Rocaglamide (Roc-A), isolated from the genus Aglaia, can be used to treat coughs, injuries, asthma, and inflammatory skin diseases. It is a potent inhibitor of NF-κB activation in T-cells. | |||
T6S0840 | Engeletin | Dihydrokaempferol 3-rhamnoside | NF-κB , Reductase |
1. Engeletin (Dihydrokaempferol 3-rhamnoside) may serve as a potential anti-inflammatory agent. 2. Engeletin possesses potent inhibition of PGE2 release with IC5 values of 19.6 μg/ml. 3. Engeletin inhibits a recombinant ... | |||
T3777 | Praeruptorin A | (+)-Praeruptorin A | CaMK , NF-κB |
Praeruptorin A ((+)-Praeruptorin A) has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin and inhibiting the Ca(2+)/calmodulin-CaMKIV-CREB-NFATc1 and/or... | |||
T6S1572 | Sauchinone | ERK , p38 MAPK , NF-κB | |
1. Sauchinone is a useful adjunctive treatment for bacterial infection. 2. Sauchinone, an active lignan found in Saururus chinensis, to regulate the activation of HSCs, to prevent liver fibrosis, and to inhibit oxidative... | |||
T6S0781 | Phellodendrine | Phallodendrin | Others , NF-κB , Akt |
1. Phellodendrine (Phallodendrin) has anti-nephritic activity, may be due to its ability to inhibit the proliferation or the migration of macrophages and cytotoxic T lymphocytes in the glomeruli. | |||
T3012 | Mangiferin | Alpizarin,Chinomin,Hedysarid | Apoptosis , Others , NF-κB , Nrf2 |
Mangiferin (Hedysarid) is used for antidiabetes. Extracted from Mangifera indica L. | |||
T2726 | Sinomenine | Cucoline,Kukoline | Apoptosis , Others , NF-κB , Opioid Receptor , Autophagy |
Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis. | |||
T2140 | Parthenolide | (-)-Parthenolide | Apoptosis , Mitophagy , NF-κB , HDAC , Autophagy |
(-)-Parthenolide ((-)-Parthenolide), an inhibitor of the Nuclear Factor-κB Pathway, also promotes the ubiquitination of MDM2 and activates p53 cellular functions. | |||
TN1341 | 8-Deoxygartanin | Beta Amyloid , NF-κB , Parasite | |
8-Deoxygartanin is a butyrylcholinesterase (BChE) selective inhibitor, it exhibits significant inhibition of self-induced α2-amyloid (Aα2) aggregation, it has multifunctional activities against Alzheimer's disease (AD) a... | |||
T5687 | WITHAFERIN A | Ferroptosis , NF-κB | |
WITHAFERIN A is a novel class of NFkappaB inhibitors, which hold promise as novel anti-inflammatory agents for treatment of various inflammatory disorders and/or cancer. | |||
TN1637 | Eurycomalactone | Anti-infection , NF-κB | |
Eurycomalactone is a natural product isolated from Eurycoma longifolia Jack., acts as a potent NF-κB inhibitor( IC50 of 0.5 μM). Eurycomalactone inhibits protein synthesis, depletes cyclin D1, but does not affect TNFα-in... | |||
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カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-05094 | Tissue Factor Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemost... | |||
TMPY-02530 | Tissue Factor Protein, Human, Recombinant (His) | Human | HEK293 |
Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemost... | |||
TMPY-01104 | Coagulation factor XI/F11 Protein, Human, Recombinant (His) | Human | HEK293 |
Factor XI (plasma thromboplastin antecedent) is a plasma glycoprotein, and a zymogen acting as a serine protease which participates in blood coagulation as a catalyst in the conversion of factor IX to factor IXa in the p... | |||
TMPY-02185 | Coagulation factor XIII B/F13B Protein, Human, Recombinant (His) | Human | HEK293 |
Coagulation factor XIII B chain, also known as Fibrin-stabilizing factor B subunit, Protein-glutamine gamma-glutamyltransferase B chain, Transglutaminase B chain and F13B, is a secreted protein which contains 1 Sushi ... | |||
TMPY-01101 | Coagulation factor X/F10 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Coagulation factor X, also known as FX, F10, Eponym Stuart-Prower factor, and thrombokinase, is an enzyme of the coagulation cascade. It is one of the vitamin K-dependent serine proteases, and plays a crucial role in the... | |||
TMPY-02215 | Coagulation factor IX/F9 Protein, Human, Recombinant (His) | Human | HEK293 |
Coagulation factor IX, also known as Christmas factor, Plasma thromboplastin component and PTC, is a secreted protein which belongs to the peptidase S1 family. Coagulation factor IX / F9 contains two EGF-like domains, on... | |||
TMPY-01075 | Von Willebrand Factor/vWF Protein, Human, Recombinant (His) | Human | CHO |
Von Willebrand Factor (VWF) is a multimeric glycoprotein involved in hemostasis in blood, binds receptors on the surface of platelets and in connective tissue, thereby mediating the adhesion of platelets to sites of vasc... | |||
TMPY-03221 | Intrinsic Factor Protein, Human, Recombinant (His) | Human | HEK293 |
Gastric intrinsic factor, also known as GIF, belongs to the of the cobalamin transport protein family. It is a glycoprotein produced by the parietal cells of the stomach. Gastric intrinsic factor plays a key role in the ... | |||
TMPY-04921 | Complement factor B/CFB Protein, Human, Recombinant (His) | Human | HEK293 |
Complement factor B/CFB Protein, Human, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 84.5 kDa. Accession number: AAH04143.1 | |||
TMPK-00993 | Coagulation Factor III/Tissue Factor Protein, Canine, Recombinant (His) | Canine | HEK293 |
Tissue factor (also named Coagulation Factor III) is a cell surface glycoprotein responsible for initiating the extrinsic pathway of coagulation.Tissue factor is the primary cellular initiator of blood coagulation via in... | |||
TMPY-02318 | Tissue Factor Protein, Rabbit, Recombinant (His) | Rabbit | HEK293 |
Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemost... | |||
TMPY-03209 | Tissue Factor Protein, Rat, Recombinant (His) | Rat | HEK293 |
Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemost... | |||
TMPJ-00301 | Coagulation Factor X Protein, Human, Recombinant (hFc) | Human | Human Cells |
F10, also known as Coagulation factor X, belongs to the peptidase S1 family that is synthesized as a 488 amino acid (aa) with a signal peptide and a pro region (residues 1‑40). Both the intrinsic and extrinsic pathways a... | |||
TMPY-02537 | Tissue Factor Protein, Human, Recombinant (hFc) | Human | HEK293 |
Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemost... | |||
TMPJ-00707 | Coagulation factor X/F10 Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
Mouse coagulation factor X / F10 a member of the peptidase S1 family. The mature F10 is composed mostly of two EGF-like domains, one Gla gamma-carboxy-glutamate domain and one peptidase S1 domain. Factor Xa is a vitamin ... | |||
TMPY-01325 | Tissue Factor Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemost... | |||
TMPH-03106 | Coagulation factor XII Protein, Pig, Recombinant (His) | Sus scrofa (Pig) | E. coli |
Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, whic... | |||
TMPY-06957 | Tissue Factor Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | HEK293 |
Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemost... | |||
TMPY-05083 | Tissue Factor Protein, Human, Recombinant (aa 1-295, His) | Human | Baculovirus-Insect Cells |
Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemost... | |||
TMPY-02014 | Coagulation factor VII/F7 Protein, Human, Recombinant (His) | Human | HEK293 |
Coagulation factor VII, also known as Serum prothrombin conversion accelerator, Factor VII, F7 and FVII, is a member of the peptidase S1 family. Factor VII is one of the central proteins in the coagulation cascade. It is... | |||
TMPY-04996 | Coagulation Factor II Protein, Rat, Recombinant (His) | Rat | HEK293 |
Coagulation Factor II Protein (FII, F2 Protein or Prothrombin) is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. Coagulation ... | |||
TMPY-06714 | Coagulation factor IX/F9 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Coagulation factor IX, also known as Christmas factor, Plasma thromboplastin component and PTC, is a secreted protein which belongs to the peptidase S1 family. Coagulation factor IX / F9 contains two EGF-like domains, on... | |||
TMPY-05355 | Coagulation factor IX/F9 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Coagulation factor IX, also known as Christmas factor, Plasma thromboplastin component and PTC, is a secreted protein which belongs to the peptidase S1 family. Coagulation factor IX / F9 contains two EGF-like domains, on... | |||
TMPH-03272 | Complement factor D Protein, Rat, Recombinant (His) | Rat | Yeast |
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classi... | |||
TMPY-02183 | Complement Factor D/CFD Protein, Human, Recombinant (His) | Human | HEK293 |
Complement factor D, also known as Adipsin, C3 convertase activator, Properdin factor D and CFD is a secreted protein which belongs to thepeptidase S1 family. CFD / Adipsin contains onepeptidase S1 domain. Complement ... | |||
TMPH-03618 | Clotting factor C Protein, Tachypleus tridentatus, Recombinant (His & Myc) | Tachypleus tridentatus | E. coli |
Clotting factor C Protein, Tachypleus tridentatus, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPK-01271 | Coagulation factor XI Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Factor XI (FXI) is the zymogen of a plasma protease (FXIa) that contributes to hemostasis by activating factor IX (FIX). In the original cascade model of coagulation, FXI is converted to FXIa by factor XIIa (FXIIa), a co... | |||
TMPH-01107 | Coagulation factor V Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Coagulation factor V Protein, Human, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPJ-00149 | Complement Factor D/CFD Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
Complement factor D, also known as adipsin, is a member of the chymotrypsin family of serine proteases, which plays an essential role in host defense as the rate-limiting enzyme in the alternative pathway of complement a... | |||
TMPH-03268 | Coagulation factor XI Protein, Rat, Recombinant (His & Myc) | Rat | E. coli |
Coagulation factor XI Protein, Rat, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPY-02167 | Complement Factor D/CFD Protein, Mouse, Recombinant (His,HEK293) | Mouse | HEK293 |
Complement factor D, also known as Adipsin, C3 convertase activator, Properdin factor D and CFD is a secreted protein which belongs to thepeptidase S1 family. CFD / Adipsin contains onepeptidase S1 domain. Complement ... | |||
TMPK-00151 | Complement Factor D/CFD Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli sugge... | |||
TMPY-01791 | Coagulation Factor II Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Coagulation Factor II Protein (FII, F2 Protein or Prothrombin) is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. Coagulation ... | |||
TMPY-04141 | Complement factor H/CFH Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Complement factor H, also known as H factor 1, and CFH, is a sialic acid containing glycoprotein that plays an integral role in the regulation of the complement-mediated immune system that is involved in microbial defens... | |||
TMPH-00020 | Elongation factor Tu Protein, Acinetobacter baumannii, Recombinant (His) | Acinetobacter baumannii | Yeast |
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. | |||
TMPH-02607 | Complement factor B Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convert... | |||
TMPJ-00166 | SCF Protein, Mouse, Recombinant | Mouse | E. coli |
Mouse stem cell factor (SCF), is the ligand for the receptor-type protein-tyrosine kinase KIT. It plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gameto... | |||
TMPK-00776 | Complement factor I Protein, Human, Recombinant (His) | Human | HEK293 |
Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for controlling the complement-mediated processes. | |||
TMPH-03273 | Complement factor I Protein, Rat, Recombinant (His & Myc) | Rat | Baculovirus |
Trypsin-like serine protease that plays an essential role in regulating the immune response by controlling all complement pathways. Inhibits these pathways by cleaving three peptide bonds in the alpha-chain of C3b and tw... | |||
TMPK-00790 | Complement factor H/CFH Protein, Human, Recombinant (His) | Human | HEK293 |
Factor H is the major soluble inhibitor of complement, where its binding to self markers (i.e., particular glycan structures) prevents complement activation and amplification on host surfaces. Not surprisingly, mutations... | |||
TMPH-03271 | Complement factor D Protein, Rat, Recombinant (His & Myc) | Rat | HEK293 |
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classi... | |||
TMPJ-00980 | Complement Factor MASP3 Protein, Human, Recombinant (His) | Human | Human Cells |
MASP3 is a member of the MASPs involved in mannan-binding lectin (MBL) complement pathway. The MBL pathway is initiated by the binding of MBL to specific carbohydrate structures found on the surface of a variety of micro... | |||
TMPK-00755 | Complement Factor D/CFD Protein, Human, Recombinant (hFc) | Human | HEK293 |
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli sugge... | |||
TMPH-03038 | Cobra venom factor Protein, Naja kaouthia, Recombinant (His & SUMO) | Naja kaouthia | E. coli |
Complement-activating protein in cobra venom. It is a structural and functional analog of complement component C3b, the activated form of C3. It binds factor B (CFB), which is subsequently cleaved by factor D (CFD) to fo... | |||
TMPY-04129 | Complement factor H/CFH Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Complement factor H, also known as H factor 1, and CFH, is a sialic acid containing glycoprotein that plays an integral role in the regulation of the complement-mediated immune system that is involved in microbial defens... | |||
TMPK-01023 | Complement factor I Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for controlling the complement-mediated processes. | |||
TMPK-00671 | Complement Factor D/CFD Protein, Rhesus macaque, Recombinant (His) | Rhesus macaque | HEK293 |
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli sugge... | |||
TMPY-04278 | LIF Protein, Mouse, Recombinant | Mouse | HEK293 |
Leukemia inhibitory factor (LIF) is a pleiotropic glycoprotein belonging to the IL-6 family of cytokines. It is involved in growth promotion and cell differentiation of different types of target cells, influence bone met... | |||
TMPY-04818 | EGFR Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p... | |||
TMPY-00117 | FGF-16 Protein, Human, Cynomolgus, Recombinant | Human,Cynomolgus | Baculovirus-Insect Cells |
Fibroblast growth factor 16 (FGF16) is preferentially expressed in the heart after birth, suggesting its regulation is associated with tissue-specific chromatin remodeling and DNA-protein interactions. Mutation of the ME... | |||
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L1380 | Transcription Factor-Targeted Compound Library | 704 compounds | |
Well-chosen 704 compounds with unique structures targeting transcription factor; | |||
L2193 | Anti-Liver Cancer Compound Library | 1816 compounds | |
1816 species of compounds related to liver cancer that can be used in anti-liver cancer drug development and pharmacological studies. | |||
L8500 | HIF-1 Signaling Pathway Compound Library | 1352 compounds | |
A unique collection of 1352 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies; | |||
L4100 | TGF-beta/Smad Compound Library | 185 compounds | |
A unique collection of 185 TGF-beta/Smad signaling targeted compounds for high throughput and high content screening; | |||
L2191 | Anti-Breast Cancer Compound Library | 1965 compounds | |
A unique collection of 1965 compounds with anti-breast cancer therapeutic activity or targeting breast cancer’s major signaling pathways, can be used for anti-breast cancer drug discovery and mechanism study; | |||
L9830 | Anti-Parkinson's Disease Compound Library | 908 compounds | |
A unique collection of 908 compounds with anti-PD activities or acting on main drug targets of PD can be used for HTS and HCS. | |||
L3800 | NF-κB Signaling Compound Library | 740 compounds | |
A unique collection of 740 compounds targeting NF-κB signaling for high throughput screening and high content screening; | |||
L6750 | PBCRBS Traditional Chinese Medicine Compound Library | 588 compounds | |
A unique collection of 588 compounds derived from traditional Chinese medicines (TCMs) for promoting blood circulation and removing blood stasis. | |||
L2550 | Glutamine Metabolism Compound Library | 580 compounds | |
A unique collection of 580 glutamine metabolism related compounds can be used for high throughput screening (HTS) and high content screening (HCS), and also is an effective tool for research in glutamine metabolism and ... | |||
L7110 | Anti-Hypertension Compound Library | 719 compounds | |
719 hypertension-related small molecules for high-throughput and high-content screening. |