Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CXCR2-IN-1 has a pIC50 of 9.3 and is a CXCR2 antagonist of the central nervous system penetration agent.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 28,000 | |||
5 mg | 在庫あり | ¥ 66,000 | |||
10 mg | 在庫あり | ¥ 95,000 | |||
25 mg | 在庫あり | ¥ 159,000 | |||
50 mg | 在庫あり | ¥ 226,000 | |||
100 mg | 在庫あり | ¥ 305,500 | |||
500 mg | 在庫あり | ¥ 610,500 |
説明 | CXCR2-IN-1 has a pIC50 of 9.3 and is a CXCR2 antagonist of the central nervous system penetration agent. |
ターゲット&IC50 | CXCR2:9.3(pIC50) |
In vitro | CXCR2 plays an important role in the activation and recruitment of neutrophils to the site of inflammation. CXCR2-IN-1 showed good central nervous system penetration characteristics (Br / Bl> 0.45)[1]. |
In vivo | CXCR2-IN-1 has shown efficacy in oral copper ketone-induced demyelination models by oral administration, providing evidence to support CXCR2 as a potential therapeutic target for the treatment of demyelinating diseases such as multiple sclerosis[1]. |
分子量 | 476.35 |
分子式 | C19H20Cl2FN3O4S |
CAS No. | 1873376-49-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 4.5 mg/mL (9.4 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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CXCR2-IN-1 1873376-49-8 Autophagy GPCR/G Protein Immunology/Inflammation CXCR CXCR-2-IN-1 CXCR2 IN 1 CXCR2IN1 Inhibitor inhibitor inhibit