Powder: -20°C for 3 years | In solvent: -80°C for 1 year
JMS-17-2 is a potent and selective antagonist of CX3CR1( IC50 : 0.32 nM).
説明 | JMS-17-2 is a potent and selective antagonist of CX3CR1( IC50 : 0.32 nM). |
ターゲット&IC50 | CX3CR1:0.32 nM |
動物実験 | SKBR3 human breast cancer cells were serum starved for four hours before being exposed to 50nM recombinant human FKN for 5 minutes, with or without previous incubation with either a CX3CR1 neutralizing antibody used at 15μg/ml or the JMS-17-2 antagonist (10nM) for 30 minutes at 37 ℃. |
分子量 | 419.95 |
分子式 | C25H26ClN3O |
CAS No. | 1380392-05-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 11 mg/mL (26.19 mM)
You can also refer to dose conversion for different animals. 詳細
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JMS-17-2 1380392-05-1 Autophagy GPCR/G Protein Immunology/Inflammation CXCR CX3CR1 inhibit GPR13 CX3C chemokine receptor1 fractalkine receptor JMS 17 2 Inhibitor JMS172 inhibitor