Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CYP11B2-IN-1 is an effective and selective inhibitor of CYP11B2 with IC50s of 2.3 nM and 142 nM for CYP11B2 and CYP11B1.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 13,500 | |||
2 mg | 在庫あり | ¥ 18,000 | |||
5 mg | 在庫あり | ¥ 27,000 | |||
10 mg | 在庫あり | ¥ 43,000 | |||
25 mg | 在庫あり | ¥ 73,500 | |||
50 mg | 在庫あり | ¥ 105,500 | |||
100 mg | 在庫あり | お問い合わせ | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 31,000 |
説明 | CYP11B2-IN-1 is an effective and selective inhibitor of CYP11B2 with IC50s of 2.3 nM and 142 nM for CYP11B2 and CYP11B1. |
ターゲット&IC50 | CYP11B2:2.3 nM, CYP11B1:142 nM |
In vitro | The IC50 of CYP11B2-IN-1 for CYP19 is 1021 nM[1]. |
In vivo | CYP11B2-IN-1 dose-dependently produces aldosterone lowering efficacy without affecting cortisol levels in rhesus pharmacodynamic models. CYP11B2-IN-1 (0.01 and 0.3 mg/kg; i.v.) reduces aldosterone AUC of 62% and 95%, respectively[1]. |
分子量 | 311.35 |
分子式 | C18H18FN3O |
CAS No. | 1356479-78-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (160.59 mM)
You can also refer to dose conversion for different animals. 詳細
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CYP11B2-IN-1 1356479-78-1 Metabolism P450 CYP11B2 IN 1 CYP-11B2-IN-1 CYP11B2IN1 Inhibitor inhibitor inhibit