Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Cefoselis Sulfate is a widely used beta-lactam antibiotic.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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5 mg | 在庫あり | ¥ 12,500 | |||
10 mg | 在庫あり | ¥ 18,500 | |||
25 mg | 在庫あり | ¥ 33,500 | |||
100 mg | 在庫あり | ¥ 91,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 17,000 |
説明 | Cefoselis Sulfate is a widely used beta-lactam antibiotic. |
In vitro | Cefoselis inhibits GABA-induced currents in a concentration-dependent manner with IC50 of 185 mM. [1] Cefoselis possesses a superior antistaphylococcal activity on MSSA isolates to both other compounds being however equal active to Cefepime and Cefpirome on multiresistant enterobacteriaceae. [2] Cefoselis is dose-dependently appeared in brain extracellular fluid in proportion to its blood level. [3] Cefoselis, a new parenteral cephalosporin, is active against clinical isolates of both gram-positive and gram-negative aerobic bacteria. [4] |
In vivo | Cefoselis elicits a massive elevation of extracellular glutamate concentration in normal rats. [3] Cefoselis (50 mg/animal)-induced convulsions are prevented by pretreatment with 5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine (MK-801), diazepam and phenobarbital (ED(50) values (mg/kg) of 0.78, 1.59 and 33.0, respectively), but not by carbamazepine or phenytoin. [5] |
別名 | FK 037 Sulfate, FK-037 |
分子量 | 620.64 |
分子式 | C19H22N8O6S2·H2SO4 |
CAS No. | 122841-12-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 27.5 mg/mL (44.31 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Cefoselis Sulfate 122841-12-7 Microbiology/Virology Antibacterial Antibiotic Cefoselis cephalosporin Gram-negative Gram-positive Bacterial FK 037 barrier FK 037 Sulfate FK037 FK-037 FK037 Sulfate Inhibitor β-lactam organisms blood-brain FK-037 Sulfate inhibit inhibitor