Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Chrysosplenol D, an efflux pump inhibitor that can potentiate the activity of commercially important antibiotics and antimalarials.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 22,500 | |||
5 mg | 在庫あり | ¥ 60,500 | |||
10 mg | 在庫あり | ¥ 95,000 | |||
25 mg | 在庫あり | ¥ 155,500 | |||
50 mg | 在庫あり | ¥ 216,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 64,000 |
説明 | Chrysosplenol D, an efflux pump inhibitor that can potentiate the activity of commercially important antibiotics and antimalarials. |
ターゲット&IC50 | Viability:11.6 µM(MDA-MB-231 TNBC cells) |
In vitro | Trace amounts of the antimalarial sesquiterpene lactone artemisinin may account for the activity of the n-hexane fraction but only the methoxylated flavonoids artemetin, chrysoplenetin, chrysosplenol-D and cirsilineol can account for the activity of the chloroform extract. These purified flavonoids were found to have IC50 values at 2.4 - 6.5 x 10(-5)M against P. falciparum in vitro compared with an IC50 value of about 3 x 10(-8)M for purified artimisinin[1] |
植物由来 |
分子量 | 360.31 |
分子式 | C18H16O8 |
CAS No. | 14965-20-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (152.65 mM)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Chrysosplenol D 14965-20-9 Immunology/Inflammation MAPK NF-Κb IL Receptor NF-κB JNK cancer Apoptosis inhibit ERK1/2 Inhibitor antitrypanosomal breast anti-inflammatory inhibitor