Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Cnidicin has anti-allergic and anti-inflammatory activity, it inhibits the degranulation of mast cell and the NO generation in RAW 264.7 cells(IC50 value, 7.5 microM). Cnidicin exhibits a significant inhibition on the proliferation of cultured human tumor cells such as A549 (non small cell lung), SK-OV-3 (ovary), SK-MEL-2 (melanoma), XF498 (central nervous system) and HCT-15 (colon) in vitro .
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 58,500 |
5 mg | 在庫あり | ¥ 129,500 |
10 mg | 在庫あり | ¥ 180,500 |
25 mg | 在庫あり | ¥ 271,000 |
50 mg | 在庫あり | ¥ 365,000 |
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 135,000 |
説明 | Cnidicin has anti-allergic and anti-inflammatory activity, it inhibits the degranulation of mast cell and the NO generation in RAW 264.7 cells(IC50 value, 7.5 microM). Cnidicin exhibits a significant inhibition on the proliferation of cultured human tumor cells such as A549 (non small cell lung), SK-OV-3 (ovary), SK-MEL-2 (melanoma), XF498 (central nervous system) and HCT-15 (colon) in vitro . |
In vitro | The hexane soluble part of the extract demonstrated a significant inhibition on the proliferation of cultured human tumor cells such as A549 (non small cell lung), SK-OV-3 (ovary), SK-MEL-2 (melanoma), XF498 (central nervous system) and HCT-15 (colon) in vitro, whereas the remaining water soluble part exhibited poor inhibition. Intensive investigation of the hexane soluble part of the extract yielded six furanocoumarins, i.e. isoimperatorin, Cnidicin, imperatorin, oxypeucedanin, byakangelicol, oxypeucedanin hydrate, all of which exhibited a significant inhibition on cell proliferation in a dose-dependent manner[1] |
植物由来 |
分子量 | 354.4 |
分子式 | C21H22O5 |
CAS No. | 14348-21-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 25 mg/mL (70.54 mM)
You can also refer to dose conversion for different animals. 詳細
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Cnidicin 14348-21-1 Immunology/Inflammation NOS NO Synthase Inhibitor inhibit inhibitor