Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Conteltinib (CT-707) is an enzyme inhibitor with antitumor activity targeting FAK, ALK, and Pyk2.Conteltinib exhibits significant inhibition of FAK, overcomes hypoxia-mediated sorafenib resistance in hepatocellular carcinoma through inhibition of YAP signaling, and can be used in advanced ALK-positive non-small-cell lung cancer and lymphoma.
説明 | Conteltinib (CT-707) is an enzyme inhibitor with antitumor activity targeting FAK, ALK, and Pyk2.Conteltinib exhibits significant inhibition of FAK, overcomes hypoxia-mediated sorafenib resistance in hepatocellular carcinoma through inhibition of YAP signaling, and can be used in advanced ALK-positive non-small-cell lung cancer and lymphoma. |
ターゲット&IC50 | FAK:1.6 nM |
別名 | SY-707, CT-707 |
分子量 | 635.82 |
分子式 | C32H45N9O3S |
CAS No. | 1384860-29-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 20 mg/mL (31.46 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Conteltinib 1384860-29-0 Angiogenesis Cytoskeletal Signaling Tyrosine Kinase/Adaptors FAK PYK2 ALK SY-707 CT 707 CT-707 CT707 Inhibitor inhibitor inhibit