Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DHMEQ racemate is an NF-κB inhibitor. The activity of DHMEQ racemate is lower than (-)-DHMEQ.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約6-8 週間 | ¥ 383,500 |
50 mg | 約6-8 週間 | ¥ 500,500 |
100 mg | 約6-8 週間 | ¥ 643,000 |
説明 | DHMEQ racemate is an NF-κB inhibitor. The activity of DHMEQ racemate is lower than (-)-DHMEQ. |
In vitro | DHMEQ racemate (DHM3EQ) and (-)-DHMEQ (DHM2EQ) inhibit TNF-a-induced NF-kB activation. (-)-DHMEQ is more effective and less toxic than DHMEQ racemate. |
In vivo | The anti-arthritis effect of (-)-DHMEQ (DHM2EQ) and DHMEQ racemate (DHM3EQ) on type II collagen-induced arthritis in DBA1/J mice was studied. Because of its pathological similarity to human rheumatoid arthritis, this animal model is widely used to evaluate anti-rheumatic drugs. Cause arthritis and score it. (-)-DHMEQ significantly inhibited type II collagen-induced arthritis in mice, while DHMEQ racemates tended to only slightly inhibit it. |
別名 | rel-DHMEQ |
分子量 | 261.23 |
分子式 | C13H11NO5 |
CAS No. | 287194-38-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 32 mg/mL (122.50 mM)
You can also refer to dose conversion for different animals. 詳細
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DHMEQ racemate 287194-38-1 NF-Κb NF-κB rel-DHMEQ Inhibitor inhibitor inhibit