Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Glabrol is a PTP1B inhibitor, it is also a CYP1B1 inhibitor, it shows inhibition of CYP1B1 in live cell assay with the IC50 value of 15uM.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 22,500 | |||
5 mg | 在庫あり | ¥ 57,500 | |||
10 mg | 在庫あり | ¥ 97,000 | |||
25 mg | 在庫あり | ¥ 157,500 | |||
50 mg | 在庫あり | お問い合わせ | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 63,500 |
説明 | Glabrol is a PTP1B inhibitor, it is also a CYP1B1 inhibitor, it shows inhibition of CYP1B1 in live cell assay with the IC50 value of 15uM. |
ターゲット&IC50 | ACAT (rat):24.6 μM (IC50) |
In vitro | Based on the bioactivities of licorice, these compounds were screened using cell- or enzyme-based bioassay methods. A total of 11 compounds exhibited potent cytotoxic activities against three human cancer cell lines (HepG2, SW480 and MCF7), while showed little toxicity on human normal cell lines LO2 and HEK293T[1] |
植物由来 |
分子量 | 392.49 |
分子式 | C25H28O4 |
CAS No. | 59870-65-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 65 mg/mL (165.61 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Glabrol 59870-65-4 Immunology/Inflammation Metabolism NF-Κb NF-κB P450 NO Synthase Acyltransferase Inhibitor mono- acylglycerol acyltransferase Diacylglycerol acyltransferase inhibit Diglyceride acyltransferase acyl-CoA:cholesterol acyltransferase inhibitor