Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DS16570511 is a novel, cell-permeable inhibitor targeting the mitochondrial calcium uniporter. It effectively blocks the increase in Ca2+ influx dependent on MCU or MICU1 [1].
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 59,500 |
5 mg | 在庫あり | ¥ 147,500 |
10 mg | 在庫あり | ¥ 209,500 |
25 mg | 在庫あり | ¥ 314,500 |
50 mg | 在庫あり | ¥ 424,500 |
100 mg | 在庫あり | ¥ 574,000 |
説明 | DS16570511 is a novel, cell-permeable inhibitor targeting the mitochondrial calcium uniporter. It effectively blocks the increase in Ca2+ influx dependent on MCU or MICU1 [1]. |
In vitro | DS16570511 effectively inhibits serum-induced mitochondrial Ca2+ (calcium) influx in HEK293A cells in a dose-dependent manner, exhibiting an IC50 value of 7 μM. Additionally, it suppresses calcium uptake in isolated mitochondria sourced from human cells, rat, and pig hearts. |
分子量 | 562.44 |
分子式 | C30H25Cl2N3O4 |
CAS No. | 2446154-84-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 124 mg/mL(220.47 mM)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
DS16570511 2446154-84-1 Membrane transporter/Ion channel Metabolism Calcium Channel DS-16570511 DS 16570511 Inhibitor inhibitor inhibit