Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Dub-in-2, with an IC50 value of 0.28 for USP8, is an effective deubiquitinase inhibitor.
説明 | Dub-in-2, with an IC50 value of 0.28 for USP8, is an effective deubiquitinase inhibitor. |
ターゲット&IC50 | USP8:0.28 μM |
In vitro | DUBs-IN-2 inhibits the viability of HCT116 colon cell line and PC-3 prostate cancer cell line with IC50 values of 0.5-1.5 μM.DUBs-IN-2 is a potent USP8 inhibitor with an IC50 of 0.28 μM, and has no effect on USP7, with an IC50 of >100 μM. |
分子量 | 275.26 |
分子式 | C15H9N5O |
CAS No. | 924296-19-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 9.06 mg/mL (32.91 mM), Sonication and heating are recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
DUB-IN-2 924296-19-5 Cell Cycle/Checkpoint DNA Damage/DNA Repair Ubiquitination DUB Inhibitor DUBs inhibit DUBIN2 Deubiquitinase DUB IN 2 inhibitor