Powder: -20°C for 3 years | In solvent: -80°C for 1 year
EF24 (3,5-Bis[(2-fluorophenyl)Methylene]-4-piperidinone) treatment increases the levels of activated caspase 3 and 9, and decreases the phosphorylated forms of MEK1 and ERK. EF24 shows potent anti-tumor activity in oral squamous cell carcinoma (OSCC) via deactivation of the MAPK/ERK signaling pathway.
説明 | EF24 (3,5-Bis[(2-fluorophenyl)Methylene]-4-piperidinone) treatment increases the levels of activated caspase 3 and 9, and decreases the phosphorylated forms of MEK1 and ERK. EF24 shows potent anti-tumor activity in oral squamous cell carcinoma (OSCC) via deactivation of the MAPK/ERK signaling pathway. |
別名 | EF 24, EF-24, 3,5-Bis[(2-fluorophenyl)Methylene]-4-piperidinone |
分子量 | 311.33 |
分子式 | C19H15F2NO |
CAS No. | 342808-40-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10mg/mL
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
EF24 342808-40-6 Apoptosis MAPK Proteases/Proteasome MEK Caspase ERK EF 24 inhibit EF-24 Inhibitor Extracellular signal regulated kinases 3,5-Bis[(2-fluorophenyl)Methylene]-4-piperidinone inhibitor