Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Nothofagin has antioxidant, and antithrombotic activities, it possesses anti-inflammatory activity by inhibiting hyperpermeability, expression of CAMs, and adhesion and migration of leukocytes, thereby endorsing its usefulness as a therapy for vascular inflammatory diseases.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 112,500 |
5 mg | 在庫あり | ¥ 250,500 |
10 mg | 在庫あり | ¥ 340,000 |
25 mg | 在庫あり | ¥ 512,000 |
50 mg | 在庫あり | ¥ 672,500 |
100 mg | 在庫あり | ¥ 911,500 |
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 282,500 |
説明 | Nothofagin has antioxidant, and antithrombotic activities, it possesses anti-inflammatory activity by inhibiting hyperpermeability, expression of CAMs, and adhesion and migration of leukocytes, thereby endorsing its usefulness as a therapy for vascular inflammatory diseases. |
In vitro | Pre-treatment of DNPHSA-stimulated RBL-2H3 with 10 μM Nothofagin markedly suppresses the phosphorylation of Lyn, Syk, and Akt. Nothofagin pre-treatment (0.1, 1, 10 μM) decreases the level of histamine release in RBL-2H3 and RPMCs cells. Furthermore, Nothofagin suppresses IgE-mediated mast cell degranulation both in vitro and in vivo [1]. |
In vivo | Oral administration of matrine at 1 mg/kg per day for 7 consecutive days significantly increases the urinary volume of both normotensive (NTR) and spontaneously hypertensive rats (SHR) [2]. |
分子量 | 436.41 |
分子式 | C21H24O10 |
CAS No. | 11023-94-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 25 mg/mL (57.29 mM)
You can also refer to dose conversion for different animals. 詳細
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Nothofagin 11023-94-2 Apoptosis Immunology/Inflammation MAPK TNF ERK IL Receptor Inhibitor inhibitor inhibit