Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Flupirtine maleate (Katadolon maleate), a centrally acting non-opioid analgesia, is the salt form of Flupirtine. It is an NMDA receptor antagonist , and also a specific neuronal potassium channel opener.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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10 mg | 在庫あり | ¥ 10,500 | |||
50 mg | 在庫あり | ¥ 13,000 | |||
100 mg | 在庫あり | ¥ 18,000 | |||
200 mg | 在庫あり | ¥ 28,500 | |||
500 mg | 在庫あり | ¥ 68,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 11,000 |
説明 | Flupirtine maleate (Katadolon maleate), a centrally acting non-opioid analgesia, is the salt form of Flupirtine. It is an NMDA receptor antagonist , and also a specific neuronal potassium channel opener. |
細胞研究 | For measurement of viability and generation of reactive oxygen intermediates, PC12 cells are seeded in 24- or 96-well plates coated with poly-L-lysine at 105 cells/mL. Drugs are dissolved in PBS (pH 7.4), or ethanol and filtered sterile. At the end of each experiment cells are trypsinized and pelleted together with cells of the culture supernatant. After staining for 10 min with 0.2% Trypan blue solution live (unstained) and dead (Trypan blue positive) cells are counted in a hemocytometer chamber. In addition, cellular viability is evaluated by the reduction of MTT to formazan. After 2 hours incubation with MTT (0.5 mg/ml) at 37 °C, cells are lysed in DMSO. Extinction at 570 nm is determined on a plate photometer. For staining of surviving adherent cells, plates are incubated for 10 min with 0.5% crystalviolet dissolved in 20% methanol. Plates are rinsed with water and stained cells are lysed in 50% ethanol, 0.1 M sodiumcitrate before determining extinction at 550 nm. (Only for Reference) |
別名 | Katadolon maleate |
分子量 | 420.39 |
分子式 | C15H17FN4O2·C4H4O4 |
CAS No. | 75507-68-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 42 mg/mL (100 mM)
Ethanol: 4.2 mg/mL (10 mM)
You can also refer to dose conversion for different animals. 詳細
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Flupirtine maleate 75507-68-5 Membrane transporter/Ion channel Neuroscience NMDAR iGluR Potassium Channel centrally acting brain,?penetrant KcsA Flupirtine Neuroprotective Inhibitor inhibit Ionotropic glutamate receptors stroke non-opioid Katadolon Maleate Katadolon maleate Flupirtine Maleate analgesic inhibitor