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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T50107 | Neuroprotective agent 1 | Others | |
ethyl 2-[3,5-bis(trifluoromethyl)phenyl]-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylate is a synthetic compound belonging to the curcumin family. It is involved in the regulation of immune response and inflammation through ... | |||
T8588 | Buramate | Antibacterial | |
Buramate is an antipsychotic and anticonvulsant. | |||
T1880 | P7C3 | Others | |
The P7C3 class of neuroprotective aminopropyl carbazoles has been shown to block neuronal cell death in models of neurodegeneration. We now show that P7C3 molecules additionally preserve axonal integrity after injury, be... | |||
T3464 | PHCCC | (-) PHCCC | GluR |
PHCCC ((-) PHCCC) is a Group I metabotropic glutamate receptor antagonist and a positive allosteric modulator of mGluR4. It also is a potent to antagonism for mGluR2 and mGluR8. | |||
T21687 | Conoidin A | Parasite | |
Conoidin A is a cell permeable inhibitor of T. gondii enzyme peroxiredoxin II (TgPrxII) with nematicidal properties. It covalently binds to the peroxidatic Cys47 of TgPrxII, irreversibly inhibiting its hyperperoxidation ... | |||
T8381 | Amodiaquine | Others , Histone Methyltransferase , Parasite | |
Amodiaquine is a synthetic aminoquinoline, used to treat malaria. | |||
T2423 | P7C3-A20 | Others | |
P7C3-A20 is a derivative of P7C3 that has proneurogenic and neuroprotective activity. | |||
T2343 | AS601245 | JNK | |
AS601245 is an inhibitor of the c-Jun NH2-terminal kinase (JNK), with neuroprotective properties. | |||
T8849 | PF-9601N | MAO | |
PF-9601N showed high potency and selectivity as a MAO-BI (monoamine oxidase type B inhibitor) and also demonstrated remarkable neuroprotective properties in several in vivo and cellular models of PD. | |||
T29123 | VU0152099 | VU 0152099,VU-0152099 | AChR |
VU0152099 is a potent and selective M4 mAChR allosteric potentiator(EC50 = 380 ± 93 nM). | |||
T7683 | Adenosine amine congener | ADAC | Adenosine Receptor |
Adenosine amine congener (ADAC) (ADAC) is an agonist of selective A1 adenosine receptor,. | |||
T39341 | FCPR03 | PDE | |
FCPR03 is a selective inhibitor of phosphodiesterase 4 (PDE4) with IC50s of 31 nM, 47 nM, and 60 nM for PDE4B1, PDE4D7, and PDE4 catalytic domain, respectively. FCPR03 has neuroprotective, anti-inflammatory, and antidepr... | |||
T21919 | UCF 101 | Apoptosis | |
UCF 101 is a specific inhibitor of HtrA2 and reduces apoptosis in PC12 cells. | |||
T23348 | SEN12333 | SEN 12333 | AChR |
SEN12333 is an α7 nicotinic acetylcholine receptor (nAChR) agonist | |||
T22749 | DR2313 | DR 2313 | PARP |
DR2313 is a competitive inhibitor of poly(ADP-ribose) polymerase (IC50: 0.20 and 0.24 μM for PARP-1 and PARP-2 respectively). It also has neuroprotective. | |||
T4283 | SRI-011381 | TGF-beta/Smad | |
SRI-011381, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease. | |||
T2009 | SB-3CT | MMP | |
SB-3CT is a potent and specific gelatinase inhibitor for MMP-2(Ki=13.9 nM) and MMP-9(Ki=600 nM). | |||
T2022 | CZC-54252 | CZC54252,CZC 54252 | LRRK2 |
CZC-54252 is a potent inhibitor of LRRK2. | |||
T39202 | CZC-54252 hydrochloride | LRRK2 | |
CZC-54252 hydrochloride is a selective inhibitor of LRRK2 with IC50s of 1.85 nM and 1.28 nM for wild-type and G2019S LRRK2. CZC-54252 hydrochloride has a neuroprotective activity and attenuates G2019S LRRK2-induced human... | |||
T5326 | Sugammadex sodium | Org25969,Sugammadex (sodium) | Others |
Sugammadex sodium (Org25969) , a synthetic derivative of γ-cyclodextrin, is a steroid-based neuromuscular blocker reversing agent. | |||
T4113 | NBQX | FG9202,NBQX disodium salt | GluR , iGluR |
NBQX (FG9202) is a potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo. | |||
T1993 | J-147 | J147 | Epigenetic Reader Domain , Dopamine Receptor , Monoamine Oxidase |
J-147 is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging. It is a curcumin derivative and a potent neurogenic and neuroprotective drug candidate... | |||
T8551 | Nitrobenzylthioinosine | NBMPR | AChR , Adenosine Receptor |
Nitrobenzylthioinosine (NBMPR) is an inhibitor of ENT1 transporter that binds to ENT1 transporter with high affinity. | |||
T6726 | VU0361737 | ML-128,VU 0361737 | GluR |
VU0361737 (ML-128) is a specific positive allosteric modulator (PAM) of mGlu4 receptor.The EC50 of VU 0361737 is 240 nM for the human receptors. The EC50 of VU 0361737 is110 nM for rat receptors.It exhibits weak activity... | |||
T7780 | Blarcamesine | AE-37,AVex-73 | AChR |
Blarcamesine (AVex-73) is a muscarinic M1 agonist potentially for the treatment of Alzheimer's disease. | |||
T1308 | Orphenadrine hydrochloride | Mebedrol,Mephenamin | Sodium Channel , NMDAR , Norepinephrine , iGluR , Histamine Receptor |
Orphenadrine hydrochloride (Mephenamin) is a muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm. | |||
T6912 | NU1025 | NSC 696807 | PARP |
NU1025 (NSC-696807) is a potent PARP inhibitor with IC50 of 400 nM. | |||
T7512 | BMS-191011 | BMS-A | Potassium Channel |
BMS-191011 (BMS-A) is an activator of large-conductance calcium-activated potassium (BKCa) channels ,effective in stroke models | |||
T14991 | CMS-121 | CMS121 | Acetyl-CoA Carboxylase |
CMS-121, a quinolone derivative, is an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor. CMS-121 protects HT22 cells against ischemia and oxidative damage (EC50: 7 nM and 200 nM). CMS-121 shows strong neuroprotect... | |||
T11393 | GET73 | Gamma hydroxybutyric acid analogue,GET 73 | GluR |
GET73 (Gamma hydroxybutyric acid analogue) is an negative allosteric modulator of mGluR5. GET73 is a naturally occurring neurotransmitter. GET73 has anti-alcohol and anxiolytic properties. | |||
T0333 | Aniracetam | Ro 13-5057 | Dopamine Receptor , 5-HT Receptor , GluR , AChR , iGluR |
Aniracetam (Ro 13-5057)(Ro 13-5057), a nootropic and neuroprotective drug, selectively modulates the AMPA receptor and nAChR. | |||
T2371 | Emapunil | AC-5216,XBD-173 | Others |
Emapunil (XBD-173) is an anxiolytic drug which acts as a selective agonist at the peripheral benzodiazepine receptor, also known as the mitochondrial 18 kDa translocator protein or TSPO. | |||
T0957 | Isradipine | PN 200-110 | Calcium Channel , Autophagy |
Isradipine (PN 200-110) is a dihydropyridine calcium channel blockers with antihypertensive and vasodilator activities. Isradipine blocks the calcium entry through the calcium ion channels of coronary and peripheral vasc... | |||
T22323 | Enoxaparin sodium | Thrombin | |
Enoxaparin sodium is a low-molecular-weight heparin (LMWH) that has recently been approved by the US FDA for use in patients with medically managed ST-segment myocardial infarction (STEMI), or STEMI with subsequent percu... | |||
T6618 | Orphenadrine Citrate | Flexon,Flexoject,Banflex | AChR , iGluR |
Orphenadrine Citrate (Flexon) is a skeletal muscle relaxant, it acts in the central nervous system to produce its muscle relaxant effects. | |||
T2607 | MSDC 0160 | CAY10415,Mitoglitazone,MSDC0160,MSDC-0160 | Others , IGF-1R , Mitochondrial Metabolism |
MSDC 0160 (CAY10415) is a prototype mTOT-modulating insulin sensitizer being used in trials studying the treatment of Type 2 Diabetes and Alzheimer's Disease. | |||
T22051 | BU 224 hydrochloride | Imidazoline Receptor | |
BU 224 hydrochloride is a selective imidazoline I(2) binding site ligand and has antinociceptive and antidepressant-like activities. | |||
T1158 | Phenoxybenzamine hydrochloride | NCI-c01661,NSC 37448,Phenoxybenzamine HCl | CaMK , Adrenergic Receptor |
Phenoxybenzamine hydrochloride (NCI-c01661) is the hydrochloride salt form of phenoxybenzamine, a synthetic, dibenzamine alpha-adrenergic antagonist with antihypertensive and vasodilatory properties. Phenoxybenzamine non... | |||
T14983 | Clomethiazole | Distraneurin,Chlormethiazole,5-(2-CHLOROETHYL)-4-METHYLTHIAZOLE | P450 , GABA Receptor |
Clomethiazole (Distraneurin) is an orally active GABAA agonist and it is an anticonvulsant agent. It also has the potential for treating convulsive status epilepticus. Chlormethiazole inhibits cytochrome P450 isoforms: C... | |||
T6504 | Flupirtine maleate | Katadolon maleate | Potassium Channel , NMDAR , iGluR |
Flupirtine maleate (Katadolon maleate), a centrally acting non-opioid analgesia, is the salt form of Flupirtine. It is an NMDA receptor antagonist , and also a specific neuronal potassium channel opener. | |||
T6478 | Donepezil Hydrochloride | Aricept,BNAG,E2020,Donepezil HCl | AChR , AChE |
Donepezil HCl(Aricept) is a selective and effective AChE inhibitor for bAChE and hAChE (IC50: 8.12/11.6 nM). | |||
T9776 | TRPM4 inhibitor 8 | TRP/TRPV Channel | |
TRPM4 inhibitor 8 is an inhibitor of Transient receptor potential melastatin 4(TRPM4) which contributes to viability, migration, cell cycle shift, and adhesion. | |||
T9157 | GP130 receptor agonist-1 | N-(4-Fluorophenyl)-4-phenyl-2-thiazolami | Interleukin |
GP130 receptor agonist-1 (N-(4-Fluorophenyl)-4-phenyl-2-thiazolami) is a potent, brain-penetrant and orally active GP130 receptor agonist. | |||
T22674 | Co 101244 hydrochloride | 4-Piperidinol, 1-[2-(4-hydroxyphenoxy)ethyl]-4-[(4-Methylphenyl)Methyl]-,hydrochloride | NMDAR |
Co 101244 hydrochloride (4-Piperidinol, 1-[2-(4-hydroxyphenoxy)ethyl]-4-[(4-Methylphenyl)Methyl]-,hydrochloride) is an NR2B-containing NMDA receptor antagonist. | |||
T0381 | Amodiaquine dihydrochloride dihydrate | Amodiaquine hydrochloride,Amodiaquin dihydrochloride dihydrate | Histone Methyltransferase , Parasite , Histamine Receptor |
Amodiaquine dihydrochloride dihydrate (Amodiaquine hydrochloride) is the hydrochloride salt of amodiaquine, an orally active 4-aminoquinoline derivative with antimalarial and anti-inflammatory properties. | |||
T19706 | Ro 20-1724 | Ro-20-1724,4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone,Ro20-1724 | PDE |
Ro 20-1724 (4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone) is a widely used inhibitor of cyclic nucleotide phosphodiesterase with IC50 of 2.0 μM and Ki of 3.1 μM. | |||
T5129 | SRI-011381 hydrochloride | SRI-011381 hydrochloride [1629138-41-5(free base)] | TGF-beta/Smad |
SRI-011381 hydrochloride, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease. | |||
T4358 | Vosilasarm | Testolone,RAD140 | Androgen Receptor |
RAD140 is an investigational selective androgen receptor modulator (SARM) for the treatment of conditions such as muscle wasting and breast cancer. | |||
T8435 | YM90K | YM90K hydrochloride,6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)- | GluR , iGluR |
YM90K (6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)-) hydrochloride is an antagonist of AMPA receptor. | |||
T23046 | N-tert-butyl-α-Phenylnitrone | (Z)-N-benzylidene-2-Methylpropan-2-aMine oxide | ROS , COX |
N-tert-butyl-α-Phenylnitrone ((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) inhibits COX2 catalytic activity. N-tert-butyl-α-Phenylnitrone((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) possesses potent reactive oxyge... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
TN1076 | Oleonuezhenide | Others | |
Oleonuezhenide is a natural product from Chinese formula Ligustrum lucidum, exerts neuroprotective effects and also considered as treatment of osteoporosis. | |||
TMS1743 | Salvigenin | MAO , Autophagy , ROS Kinase | |
Salvigenin is a potent hMAO-A inhibitor, has neuroprotective, antitumor and immunomodulatory effects. | |||
T6S2227 | Spinosin | Flavoayamenin | Others |
1. Spinosin (Flavoayamenin) ameliorated memory impairment induced through AβO, the serotonergic neurotransmitter system, and these effects were regulated, in part, through neuroprotective activity via the anti-inflammato... | |||
TN1772 | Isoastilbin | Anti-infection , Tyrosinase , Antibacterial | |
Isoastilbin is a dihydroflavonol glycoside compound in Rhizoma Smilacis glabrae and Astragalus membranaceus. Isoastilbin inhibits glucosyltransferase (GTase) with an IC50 value of 54.3 μg/mL, Isoastilbin has anti-acne an... | |||
T3236 | Solanesol | Betulanonaprenol,Nonaisoprenol | Others , Endogenous Metabolite , Antibacterial |
Solanesol (Betulanonaprenol) is a phytochemical present in tobacco leaf. Starting material for synthesis of co-enzyme Q10. Exhibits antiulcer activity. | |||
T3769 | Tenuifolin | Others , Beta-Secretase , AChE | |
Tenuifolin has no inherent toxicity to either the transfected or wild type cells at the effective concentrations, it inhibits amyloid-β secretion in vitro. | |||
TN2085 | Piperlonguminine | Anti-infection , Antibacterial , Antifungal | |
Piperlonguminine is an alkaloid amide isolated from the Piper species. Piperlonguminine shows anti-inflammatory, antitumor, neuroprotective, anti-platelet, anti-melanogenic, antifungal and antibacterial activities.Piperl... | |||
T3S0195 | Nootkatone | AMPK | |
1. Nootkatone can provide effective tick control. 2. (+)-Nootkatone has antiallergic, anti-inflammatory, and antiplatelet activities. 3. Nootkatone can prevent obesity and improve physical performance through AMPK activa... | |||
TN2082 | Pinostrobin | Beta Amyloid , IL Receptor , Serine/threonin kinase , TNF | |
Pinostrobin, a potent flavonoid inducer, exerts a neuroprotective effect against Aα²(25-35)-induced neurotoxicity in PC12 cells, at least in part, via inhibiting oxidative damage and calcium overload, as well as suppress... | |||
T12095 | Monomethyl fumarate | GPR , Drug Metabolite | |
Monomethyl fumarate is a potent agonist of GPR109A . | |||
T2780 | Catalpol | Catalpinoside,Digitalis purpurea L | Others , HBV |
Catalpol (Catalpinoside) is an iridoid glycoside with neuroprotective, anti-inflammatory, and anti-hepatitis virus effects. | |||
T2786 | Oxysophocarpine | Prostaglandin Receptor | |
Oxysophocarpine is extracted from Sophra flavescens Ait. | |||
T6S0721 | Orientin | Lutexin,Luteolin-8-glucoside | Others |
1. Orientin (Luteolin-8-glucoside) may be regarded as a candidate therapeutic agent for treatment of vascular inflammatory diseases via inhibition of the HMGB1 signaling pathway. 2. Orientin protects vascular barrier int... | |||
T3866 | Macelignan | Anwuligan,(+)-Anwulignan | Others , COX |
Macelignan (Anwuligan) is a lignan isolated from nutmeg with antimicrobial and anticariogenic activity against Streptococcus mutans and other streptococcus species. | |||
T3773 | Oxypaeoniflorin | Oxypaeoniflora | Others |
Oxypaeoniflorin a monoterpene glycoside compound isolated from Paeoniae, is an antioxidant, is neuroprotective and anti-inflammatory. | |||
T5654 | Musk ketone | Others | |
Musk ketone can induce the growth repression and the apoptosis of cancer cells. Musk ketone increases activity of glutathione S-transferase and thus may prove to be useful cancer chemoprotectant. | |||
T6S1653 | Albiflorin | Alibiflorin | Reactive Oxygen Species |
1. Albiflorin (Alibiflorin) has anticonvulsant effect for pain relief. 2. Albiflorin and paeoniflorin has neuroprotective action against Glu toxicity. 3. Albiflorin and paeoniflorin significantly ameliorated Glu-induced ... | |||
T4S2126 | Ginkgetin | Apoptosis , Wnt/beta-catenin , COX , STAT , Autophagy | |
1. Ginkgetin has anti-influenza virus and anti-fungal activities. 2. Ginkgetin has anti-inflammatory activity, can down-regulates COX-2 induction in vivo against skin inflammatory responses. 3. Ginkgetin is a good STAT3 ... | |||
TN2423 | Safranal | Antioxidant | |
Safranal is the special volatile aroma compound of saffron | |||
T7983 | Isoborneol | DL-Isoborneol | HSV |
Isoborneol (DL-Isoborneol) is a monoterpene alcohol, with neuroprotective and antiviral activities | |||
TN1911 | Marein | transporter , Akt , HDAC , AMPK | |
Marein shows neuroprotective effect on PC12 cell damage induced by methylglyoxal, which is due to a reduction of damage to mitochondria function and activation of the AMPK signal pathway, it may be a potent compound for ... | |||
T1032 | Erythromycin | E-Mycin | ribosome , Antibacterial , Antibiotic |
Erythromycin (E-Mycin) is a Macrolide and Macrolide Antimicrobial. The physiologic effect of erythromycin is by means of Decreased Sebaceous Gland Activity. | |||
T3416 | Aucubin | Aucuboside,Rhinanthin | IL Receptor , NF-κB , Antibacterial |
Aucubin (Rhinanthin) is an iridoid glycoside with anti-inflammatory, anti-microbial, anti-algesic as well as anti-tumor activities. | |||
T0795 | Rutin | Quercetin 3-O-rutinoside,Rutoside | Beta Amyloid , Prostaglandin Receptor , Autophagy |
Rutin (Quercetin 3-O-rutinoside), a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarcinogenic properties. | |||
T0492 | Dimethyl fumarate | DMF | Reactive Oxygen Species , HIV Protease , Nrf2 , Endogenous Metabolite , Autophagy |
Dimethyl fumarate (DMF), a fumarate derivative, is used as antiinflammatory and immunomodulatory agent. | |||
T2899 | Liquiritin | Liquiritigenin-4'-O-glucoside,Liquiritoside | Reactive Oxygen Species |
Liquiritin (Liquiritigenin-4'-O-glucoside) (LIQ) is a main component among the licorice flavonoids, and possesses anti-inflammatory and anti-cancer abilities. | |||
T8516 | Levomenol | (-)-α-BISABOLOL | Others |
Levomenol ((-)-α-BISABOLOL) is a sesquiterpene alcohol that has been found in the essential oils of several aromatic plants, with exerts antioxidant, anti-inflammatory, and anti-apoptotic activities. | |||
T2800 | L-Theanine | Apoptosis , Others | |
L-Theanine is a relaxing and nondietary amino acid found pretty much exclusively in teas from Camellia sinensis and is known to promote relaxation without sedation. | |||
T0437 | Inosine | INO 495,NSC 20262 | ROS , Endogenous Metabolite , Adenosine Receptor |
Inosine (NSC-20262) is a purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It has immunomodulatory, neuroprotective, and analgesic properties. | |||
T6780 | Benzamide | Amid kyseliny benzoove,Phenylcarboxyamide,Benzoylamide | PARP , Endogenous Metabolite |
Benzamide (Amid kyseliny benzoove), an inhibitor of poly(ADP-ribose) polymerase, is a derivative of benzoic acid. | |||
T26288 | Clovamide | trans-Clovamide,N-trans-Caffeoy-L-dopa | Apoptosis , Influenza Virus , ROS , Antibacterial |
Trans-Clovamide (trans-Clovamide) is a naturally occurring caffeoyl conjugate identified in the antioxidant polyphenolic fraction of cocoa (T. cacao L.) Trans-Clovamide is a potent antioxidantand that has shown neuroprot... | |||
T3933 | Jatrorrhizine | Yatrorizine,neprotin | MAO , 5-HT Receptor , Antibacterial , AChE |
Jatrorrhizine (neprotin) is a protoberberine alkaloid isolated from Enantia chlorantha (Annonaceae) and other species. It was found to have antimicrobial and antifungal activity. It binds and noncompetitively inhibits mo... | |||
TN2883 | 3',4'-Dimethoxyflavone | Others , PARP | |
3',4'-Dimethoxyflavone is a reference standard for flavonoid compounds, which have a variety of medicinal activities. | |||
T5728 | OsMundacetone | 4-(3,4-Dihydroxyphenyl)-3-buten-2-one | Apoptosis , Reactive Oxygen Species |
OsMundacetone (4-(3,4-Dihydroxyphenyl)-3-buten-2-one) is a natual product isolated from Rhizoma osmundae. | |||
T22417 | Rutin hydrate | Rutoside,Sophorin,Quercetin-3-O-rutinoside | Beta Amyloid , Others , Autophagy |
Rutin hydrate (Sophorin), a kind of glycoside, widely exists in many plants including citrus fruit. | |||
T2902 | Costunolide | Costus lactone,NSC 106404,Costunolid,(+)-Costunolide | Apoptosis , Endogenous Metabolite , Telomerase |
Costunolide (Costus lactone) has anti-inflammatory and anti-oxidant properties and mediates apoptosis. | |||
T6S1525 | 3,4-Dicaffeoylquinic acid | Isochlorogenic acid B | Apoptosis , Antioxidant , Influenza Virus , Endogenous Metabolite |
3,4-Dicaffeoylquinic acid (Isochlorogenic acid B) has antioxidant activity. | |||
T4S1659 | Xanthotoxol | 8-Hydroxypsoralen,8-Hydroxyfuranocoumarin,Psoralen,8-Hydroxypsoralene | Reactive Oxygen Species , 5-HT Receptor , Endogenous Metabolite |
Xanthotoxol (Psoralen) is a biologically active linear furocoumarin, shows strong pharmacological activities as anti-inflammatory, antioxidant, 5-HT antagonistic, and neuroprotective effects. | |||
T3S1068 | Oxyresveratrol | trans-Oxyresveratrol,2,3',4,5'-tetrahydroxystilbene,Tetrahydroxystilbene | Tyrosinase , Autophagy , HSV |
1. Oxyresveratro can inhibit tyrosinase activity. 2. Oxyresveratro is useful to trauma models, as toxicity to glia could be beneficial by inhibiting reactive gliosis. 3. Oxyresveratrol (trans-Oxyresveratrol) has antioxid... | |||
T3026 | (-)-Huperzine A | HupA,Huperzine A | Apoptosis , AChR , AChE , iGluR |
(-)-Huperzine A (HupA) , an active Lycopodium alkaloid extracted from the traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the tr... | |||
T4912 | Jatrorrhizine chloride | Yatrorhizine chloride,Neprotine chloride | Others , 5-HT Receptor , OCT , Antibacterial , AChE |
Jatrorrhizine chloride (Neprotine chloride) is a potent and orally active uptake-2 transporter inhibitor. It exhibits a critical neuroprotective role in H2O2-induced apoptosis via inhibition of the MAPK pathway in HT22 h... | |||
T4036 | Solasodine | Solancarpidine,Purapuridine,Solasodin | Apoptosis , Others , E1/E2/E3 Enzyme , Antifungal |
Solasodine (Purapuridine)(Purapuridine) is a poisonous alkaloid chemical compound that occurs in plants of the Solanaceae family. Solasodine showed selective cytotoxicity against cervical cancer cell line (HeLa) and huma... | |||
T9454 | 4-Hydroxyestrone | Estrogen Receptor/ERR , Endogenous Metabolite | |
4-Hydroxyestrone, an endogenous estrogen metabolite, can strongly protect neuronal cells against oxidative damage. | |||
T3388 | Calycosin-7-O-β-D-glucoside | calycosin-7-O-beta-D-glucopyranoside,Calycosin-7-O-beta-D-glucoside | MMP , Reactive Oxygen Species |
Calycosin-7-O-β-D-glucoside (calycosin-7-O-beta-D-glucopyranoside) possesses a protective effect on rat hepatocytes, an inhibitory effect on COX-2 activity. Calycosin 7-O-β-D-glucoside has antimicrobial activity. Calycos... | |||
T36857L | Premarin | Estrone 3-sulfate,Estrone sulfate | Estrogen Receptor/ERR |
Premarin (Estrone 3-sulfate) is an an estrogen sulfate with neuroprotective actions during traumatic brain injury. | |||
T3697 | 3',6-Disinapoylsucrose | Disinapoyl sucrose,3,6'-Disinapoyl sucrose | BCL , Epigenetic Reader Domain |
3',6-Disinapoylsucrose (Disinapoyl sucrose) shows the neuroprotective effect and antidepressive activity in rats. | |||
T0136 | Citicoline | CDP-Choline,Citicholine,cytidine 5'-diphosphocholine,cytidine diphosphate-choline | Apoptosis , Dopamine Receptor , Endogenous Metabolite |
Citicoline (CDP-Choline) is an intermediate in the synthesis of phosphatidylcholine, a component of cell membranes. Citicoline exerts neuroprotective effects. | |||
Fr12596 | 3-Acetylcoumarin | Others | |
3-Acetylcoumarin as a practical ligand for copper-catalyzed CN coupling reactions at room temperature. It has neuroprotective and acaricidal properties. | |||
T5721 | Dehydroevodiamine hydrochloride | AChE | |
Dehydroevodiamine (DHE), a natural compound isolated from Evodia rutaecarpa, can inhibit AChE. It has hypotensive and neuroprotective effects and modulates nitric oxide production. | |||
T3856 | Tenuifoliside A | ERK , Others | |
Tenuifoliside A has anti-apoptotic , neuroprotective activity. And tenuifoliside A has anti-inflammatory effect, which is mediated by the inhibition of the NF-κB and MAPK pathways. | |||
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カタログ番号 | 製品名 | Species | Expression System |
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TMPK-00810 | TPA Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Tissue plasminogen activator (tPA) is the predominant plasminogen activator present in the vascular and nervous systems.t tPA is not only neuroprotective for postnatal primary cortical neurons, but also that the predomin... | |||
TMPH-03391 | TRIM2 Protein, Rat, Recombinant (His) | Rat | E. coli |
E3 ubiquitin-protein ligase that mediates the ubiquitination of phosphorylated BCL2L11. Also mediates the UBE2D1-dependent ubiquitination of NEFL. Plays a neuroprotective function. May play a role in neuronal rapid ische... | |||
TMPH-01502 | Humanin Protein, Human, Recombinant (GST) | Human | E. coli |
Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective e... | |||
TMPJ-00990 | S100B Protein, Mouse, Recombinant (His) | Mouse | E. coli |
S100-B, is an acidic protein with a molecular weight of 21 kDa belonging to the S100 family. S100-B contains two EF-hand-type calcium-binding motifs separated by a hinge region with a hydrophobic cleft. S100-B plays an i... | |||
TMPH-01503 | Humanin Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective e... |
カタログ番号 | 製品名 | ||
---|---|---|---|
L5900 | CNS-Penetrant Compound Library | 509 compounds | |
A unique collection of 509 CNS-Penetrant compounds for high throughput screening (HTS) and high content screening (HCS); | |||
L6110 | Alkaloid Natural Product Library | 464 compounds | |
A unique collection of 464 natural alkaloids can be used for high throughput and high content screening; | |||
L6140 | Saccharide and Glycoside Natural Product Library | 595 compounds | |
A unique collection of 595 saccharides and glycosides compounds can be used for HTS and HCS; | |||
L6750 | PBCRBS Traditional Chinese Medicine Compound Library | 580 compounds | |
A unique collection of 580 compounds derived from traditional Chinese medicines (TCMs) for promoting blood circulation and removing blood stasis. | |||
L6820 | Tobacco Monomer Library | 747 compounds | |