Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Velsecorat (AZD7594) is an effective and selective nonsteroidal glucocorticoid receptor modulator (IC50: 0.9 nM).
説明 | Velsecorat (AZD7594) is an effective and selective nonsteroidal glucocorticoid receptor modulator (IC50: 0.9 nM). |
ターゲット&IC50 | GR:0.9 nM (IC50) |
In vitro | AZD7594 shows no effect on progesterone receptor, mineralocorticoid receptor, Androgen receptor, ERα or ERβ (IC50, > 10 μM). |
In vivo | AZD7594 has anti-inflammatory activity and efficiently inhibits rat lung edema. AZD5423 displayed a potent inhibition of lung edema in a rat model of allergic airway inflammation following dry powder inhalation. |
別名 | AZD7594, AZ13189620 |
分子量 | 606.62 |
分子式 | C32H32F2N4O6 |
CAS No. | 1196509-60-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 79 mg/mL (130.23 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Velsecorat 1196509-60-0 Endocrinology/Hormones Glucocorticoid Receptor Inhibitor AZ 13189620 AZD 7594 AZD-7594 AZD7594 AZ-13189620 inhibit AZ13189620 inhibitor