Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ICCB-19 hydrochloride (ICCB-19 HCl) is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain). It binds to a pocket on the N-terminal TRAF2-binding domain of TRADD (TRADD-N), which interacts with the C-terminal domain (TRADD-C) and TRAF2 to modulate the ubiquitination of RIPK1 and beclin 1.
説明 | ICCB-19 hydrochloride (ICCB-19 HCl) is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain). It binds to a pocket on the N-terminal TRAF2-binding domain of TRADD (TRADD-N), which interacts with the C-terminal domain (TRADD-C) and TRAF2 to modulate the ubiquitination of RIPK1 and beclin 1. |
別名 | ICCB-19 HCl(750621-52-4 free base) |
分子量 | 291.84 |
分子式 | C12H22ClN3OS |
CAS No. | 1803605-68-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 25 mg/mL (85.66 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
ICCB-19 hydrochloride 1803605-68-6 Apoptosis Autophagy NF-Κb Others RIP kinase ICCB19 ubiquitination 750621-52-4 cIAP2 TRADD cIAP1 RDA ICCB 19 hydrochloride Receptor-interacting protein kinases ICCB-19 HCl ICCB 19 beclin1 ICCB-19 HCl(750621-52-4 free base) ICCB 19 Hydrochloride RIPK ICCB19 Hydrochloride k63 Inhibitor RIPK1 ICCB19 hydrochloride 750621-52-4 free base inhibit ICCB-19 Hydrochloride ICCB-19 inhibitor