Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Iberin (NSC-321801) induces apoptosis and inhibits cell survival (IC50 = 2.3 μM). Iberin is an analog of sulforaphane.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 13,500 | |||
5 mg | 在庫あり | ¥ 31,500 | |||
10 mg | 在庫あり | ¥ 45,500 | |||
25 mg | 在庫あり | ¥ 75,500 | |||
50 mg | 在庫あり | ¥ 113,000 | |||
100 mg | 在庫あり | ¥ 164,500 | |||
500 mg | 在庫あり | ¥ 340,000 |
説明 | Iberin (NSC-321801) induces apoptosis and inhibits cell survival (IC50 = 2.3 μM). Iberin is an analog of sulforaphane. |
ターゲット&IC50 | Cell survival:2.3 μM |
In vitro | Iberin inhibits neuroblastoma cell growth in a dose- and time-dependent manner and inhibits the expression of cyclin-dependent kinase Cdk2, Cdk4, and Cdk6 proteins. Iberin increases the apoptotic cell death and activates caspase-9, caspase-3, and PARP[2]. |
In vivo | Iberin enhances tissue levels of the phase II detoxification enzymes quinone reductase and GST in a variety of rat tissues[5]. |
別名 | NSC 321801 |
分子量 | 163.26 |
分子式 | C5H9NOS2 |
CAS No. | 505-44-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 9.0 mg/mL (55.1 mM), Sonication is recommended.
DMSO: 279.0 mg/mL (1708.9 mM)
You can also refer to dose conversion for different animals. 詳細
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Iberin 505-44-2 Metabolism Endogenous Metabolite NSC321801 NSC 321801 NSC-321801 Inhibitor inhibitor inhibit