Powder: -20°C for 3 years | In solvent: -80°C for 1 year
JNJ-DGAT2-A, a specific inhibitor of DGAT2(IC50 = 0.14 μM), can be used in studies about the synthesis of triglycerides.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 15,500 | |||
5 mg | 在庫あり | ¥ 37,500 | |||
10 mg | 在庫あり | ¥ 66,500 | |||
25 mg | 在庫あり | ¥ 133,000 | |||
50 mg | 在庫あり | ¥ 191,500 | |||
100 mg | 在庫あり | ¥ 264,000 | |||
500 mg | 在庫あり | ¥ 525,500 |
説明 | JNJ-DGAT2-A, a specific inhibitor of DGAT2(IC50 = 0.14 μM), can be used in studies about the synthesis of triglycerides. |
ターゲット&IC50 | DGAT-2 (Sf9 insect cell membranes ):0.14 μM |
In vitro | JNJ-DGAT2-A (5 μM) almost completely inhibits the enzymatic activity of recombinant DGAT2 and DGAT2 activity in HepG2 cell lysates. In HepG2 cells, JNJ-DGAT2-A (0.3125-20 µM) inhibits the generation of TG (50:2), TG (52:2), and TG (54:3) in a dose-dependent manner with IC50 values of 0.66, 0.85, and 0.99 μM, respectively[1]. |
別名 | JNJDGAT2A |
分子量 | 523.38 |
分子式 | C24H16BrFN4O2S |
CAS No. | 1962931-71-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 3.0 mg/mL (5.7 mM), Sonication and heating to 60℃ are recommended.
You can also refer to dose conversion for different animals. 詳細
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JNJ-DGAT2-A 1962931-71-0 Metabolism Transferase JNJ DGAT2 A JNJ-DGAT-2-A JNJDGAT2A Inhibitor inhibitor inhibit