Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Arglabin ((+)-Arglabin) is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 24,500 | |||
5 mg | 在庫あり | ¥ 58,000 | |||
10 mg | 在庫あり | ¥ 87,000 | |||
25 mg | 在庫あり | ¥ 125,500 | |||
50 mg | 在庫あり | ¥ 167,000 | |||
100 mg | 在庫あり | ¥ 250,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 75,000 |
説明 | Arglabin ((+)-Arglabin) is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects. |
In vitro | Arglabin-stimulated macrophages displayed a strong cytotoxic activity and the lowest doses (1.25 μg/mL and 0.125 μg/mL) induced a significant stimulation of cell mitochondrial metabolism, which correlated with [3H]TdR uptake by J774.1 cells under the same experimental conditions. Arglabin triggered the production of the three cytokines from J774-1 cells [1]. Arglabin exhibits anti exudative and antiproliferative properties on the models of acute aseptic inflammation caused by formalin, carrageenan, and histamine, and on the model of proliferative inflammation accompanying cotton-pellet granuloma [2]. Arglabin is able to reduce the proportion of AML stem cells (CD34+CD38-) in primary AML cells [3]. |
植物由来 |
別名 | (+)-Arglabin |
分子量 | 246.3 |
分子式 | C15H18O3 |
CAS No. | 84692-91-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 95 mg/mL (385.7 mM)
You can also refer to dose conversion for different animals. 詳細
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Arglabin 84692-91-1 Autophagy Immunology/Inflammation Metabolism NF-Κb NOD-like Receptor (NLR) Transferase NOD inflammasome Ftase anti-inflammatory Farnesyl Transferase antitumor RAS Inhibitor proto-oncogene inhibit (+)-Arglabin inhibitor