keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Juglone (Regianin) is a natural naphthoquinone found in the black walnut (J. nigra) and other plants in the Juglandaceae family. Juglone also irreversibly inhibits peptidyl-prolyl cis/trans isomerases of the parvulin family, including human Pin1, yeast Ess1/Ptf1, and E. coli parvulin (Ki = 55.9 nM). Juglone also blocks transcription by RNA polymerases I, II, and III (IC50s = 2-7 μM) and attenuates kidney fibrosis in rats treated with unilateral ureteral obstruction, both through Pin1-independent mechanisms.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
5 mg | 在庫あり | ¥ 9,500 | |||
10 mg | 在庫あり | ¥ 13,000 | |||
25 mg | 在庫あり | ¥ 22,000 | |||
50 mg | 在庫あり | ¥ 31,000 | |||
100 mg | お問い合わせ | ¥ 43,500 |
説明 | Juglone (Regianin) is a natural naphthoquinone found in the black walnut (J. nigra) and other plants in the Juglandaceae family. Juglone also irreversibly inhibits peptidyl-prolyl cis/trans isomerases of the parvulin family, including human Pin1, yeast Ess1/Ptf1, and E. coli parvulin (Ki = 55.9 nM). Juglone also blocks transcription by RNA polymerases I, II, and III (IC50s = 2-7 μM) and attenuates kidney fibrosis in rats treated with unilateral ureteral obstruction, both through Pin1-independent mechanisms. |
植物由来 |
別名 | 5-Hydroxy-1,4-naphthoquinone, Regianin |
分子量 | 174.15 |
分子式 | C10H6O3 |
CAS No. | 481-39-0 |
keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 5.56 mg/mL (31.9 mM), The compound is unstable in solution. Please use soon.
Ethanol: 15 mg/mL
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Juglone 481-39-0 Cell Cycle/Checkpoint DNA Damage/DNA Repair Microbiology/Virology Antibacterial DNA/RNA Synthesis antimicrobial Pigment inhibit Bacterial 5-Hydroxy-1,4-naphthoquinone Inhibitor Yellow black walnut Regianin inhibitor