Powder: -20°C for 3 years | In solvent: -80°C for 1 year
POL1-IN-1 (Compound 3A) can effectively inhibit the transcription of RNA polymerase I in the A375 malignant melanoma cell line but has no effect on polymerase II.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 9,500 | |||
5 mg | 在庫あり | ¥ 22,500 | |||
10 mg | 在庫あり | ¥ 34,000 | |||
25 mg | 在庫あり | ¥ 52,500 | |||
50 mg | 在庫あり | ¥ 79,000 | |||
100 mg | 在庫あり | ¥ 114,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 24,000 |
説明 | POL1-IN-1 (Compound 3A) can effectively inhibit the transcription of RNA polymerase I in the A375 malignant melanoma cell line but has no effect on polymerase II. |
In vivo | Corynoxine promotes the formation of autophagosomes in the fat bodies of Drosophila. By inducing autophagy, Corynoxine promotes the clearance of wild-type and A53T α-syn in inducible PC12 cells. Corynoxine induces autophagy through the Akt/mTOR pathway as evidenced by the reduction in the levels of phospho-Akt, phospho-mTOR and phospho-p70 S6 Kinase [1]. Corynoxine significantly decreased locomotor activity after oral administration to mice [2]. |
別名 | Compound 3A |
分子量 | 356.42 |
分子式 | C21H20N6 |
CAS No. | 1822358-25-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 3.57 mg/mL (10 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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POL1-IN-1 1822358-25-7 Cell Cycle/Checkpoint DNA Damage/DNA Repair DNA/RNA Synthesis POL1 IN 1 POL-1-IN-1 proliferation inhibit cancer Inhibitor cell transcription Compound 3A POL1IN1 inhibitor