Powder: -20°C for 3 years | In solvent: -80°C for 1 year
KLH45 is an effective and selective inhibitor of Spastic Paraplegia-Related Triglyceride Hydrolase DDHD2(IC50 = 1.3 nM).
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 9,500 | |||
5 mg | 在庫あり | ¥ 22,500 | |||
10 mg | 在庫あり | ¥ 35,500 | |||
25 mg | 在庫あり | ¥ 72,000 | |||
50 mg | 在庫あり | ¥ 114,000 | |||
100 mg | 在庫あり | ¥ 166,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 22,500 |
説明 | KLH45 is an effective and selective inhibitor of Spastic Paraplegia-Related Triglyceride Hydrolase DDHD2(IC50 = 1.3 nM). |
In vitro | In Neuro2A cells, KLH45 (25 nM) completely inhibits DDHD2 (>95%)[1]. In fatty acid-supplemented DDHD2-expressing cells, KLH45 (2 μM) increases LD formation and selectively blocks DDHD2 activity[2]. |
In vivo | KLH45 (20 mg/kg) significantly elevates brain triglycerides in DDHD2−/− mice[1]. |
別名 | KLH-45, KLH 45 |
分子量 | 458.48 |
分子式 | C24H25F3N4O2 |
CAS No. | 1632236-44-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 162.0 mg/mL (353.3 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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KLH45 1632236-44-2 Metabolism Phosphatase KLH-45 KLH 45 Inhibitor inhibitor inhibit