Powder: -20°C for 3 years | In solvent: -80°C for 1 year
LDN-91946 is an effective and selective inhibitor of ubiquitin C-terminal hydrolase-L1 (UCH-L1) (Ki = 2.8 μM).
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
10 mg | 在庫あり | ¥ 9,000 | |||
25 mg | 在庫あり | ¥ 15,000 | |||
50 mg | 在庫あり | ¥ 22,500 | |||
100 mg | 在庫あり | ¥ 33,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 10,000 |
ターゲット&IC50 | UCHL1: 2.8 μM(ki) |
In vitro | LDN-91946 demonstrates no inhibitory activity against TGase 2, Papain, and Caspase-3 at concentrations of 40 μM, and remains inactive against UCH-L3 at 20 μM. Furthermore, it exhibits no cytotoxic effects on serum-starved Neuro 2A (N2A) cells even at concentrations up to 0.1 mM[1]. |
分子量 | 314.32 |
分子式 | C15H10N2O4S |
CAS No. | 439946-22-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 83 mg/mL (264.06 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
LDN-91946 439946-22-2 Cell Cycle/Checkpoint DNA Damage/DNA Repair Ubiquitination DUB LDN91946 Inhibitor Ubiquitin LDN 91946 inhibit Deubiquitinase UCH-L1 DUBs selective inhibitor