Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Selective tryptophan 2, 3-dioxygenase (TDO) inhibitor (IC50 values are 0.62 and 2 μM for human and mouse TDO, respectively). Exhibits selectivity for TDO over IDO, MAO-A, MAO-B, and a panel of receptors and transporters. Reduces growth of TDO-expressing P815 mastocytoma tumors in mice. Orally bioavailable.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
10 mg | 在庫あり | ¥ 9,000 | |||
25 mg | 在庫あり | ¥ 18,500 | |||
50 mg | 在庫あり | ¥ 34,000 | |||
100 mg | 在庫あり | ¥ 57,000 | |||
200 mg | 在庫あり | ¥ 84,500 | |||
500 mg | 在庫あり | ¥ 137,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 7,000 |
説明 | Selective tryptophan 2, 3-dioxygenase (TDO) inhibitor (IC50 values are 0.62 and 2 μM for human and mouse TDO, respectively). Exhibits selectivity for TDO over IDO, MAO-A, MAO-B, and a panel of receptors and transporters. Reduces growth of TDO-expressing P815 mastocytoma tumors in mice. Orally bioavailable. |
ターゲット&IC50 | TDO (human):0.62 μM, TDO (mouse):2 μM |
分子量 | 229.21 |
分子式 | C11H8FN5 |
CAS No. | 1316695-35-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 4.58 mg/mL(20 mM)
DMSO: 22.92 mg/mL(100 mM)
You can also refer to dose conversion for different animals. 詳細
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