Powder: -20°C for 3 years | In solvent: -80°C for 1 year
LMT-28 is an inhibitor of IL-6 and selectively inhibits IL-6-induced phosphorylation of gp130, STAT3, and JAK2.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 7,500 | |||
5 mg | 在庫あり | ¥ 15,000 | |||
10 mg | 在庫あり | ¥ 26,000 | |||
25 mg | 在庫あり | ¥ 57,000 | |||
50 mg | 在庫あり | ¥ 89,500 | |||
100 mg | 在庫あり | ¥ 130,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 16,000 |
説明 | LMT-28 is an inhibitor of IL-6 and selectively inhibits IL-6-induced phosphorylation of gp130, STAT3, and JAK2. |
In vitro | LMT-28 (1-10000 nM) inhibits IL-6-induced cell proliferation(IC50 = 7.5 μM)[1]. |
In vivo | In male DBA/1J collagen-induced arthritis mice, LMT-28 (0-0.5 mg/kg) reduces the serum levels of cartilage oligomeric matrix protein, serum amyloid P and anti-CII IgG by 50%, 55%, and 62%[1]. |
分子量 | 311.42 |
分子式 | C17H29NO4 |
CAS No. | 1239600-18-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90.0 mg/mL (289.0 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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LMT-28 1239600-18-0 Immunology/Inflammation IL Receptor LMT28 LMT 28 Inhibitor inhibitor inhibit